| Mitochondrial integrity regulated by lipid metabolism is a cell-intrinsic checkpoint for Treg suppressive function CS Field, F Baixauli, RL Kyle, DJ Puleston, AM Cameron, DE Sanin, ... Cell metabolism 31 (2), 422-437. e5, 2020 | 305 | 2020 |
| Acetate promotes T cell effector function during glucose restriction J Qiu, M Villa, DE Sanin, MD Buck, D O’Sullivan, R Ching, M Matsushita, ... Cell reports 27 (7), 2063-2074. e5, 2019 | 287 | 2019 |
| Polyamine metabolism is a central determinant of helper T cell lineage fidelity DJ Puleston, F Baixauli, DE Sanin, J Edwards-Hicks, M Villa, AM Kabat, ... Cell 184 (16), 4186-4202. e20, 2021 | 215 | 2021 |
| Triacylglycerol synthesis enhances macrophage inflammatory function A Castoldi, LB Monteiro, N van Teijlingen Bakker, DE Sanin, N Rana, ... Nature communications 11 (1), 4107, 2020 | 189 | 2020 |
| Metabolic conditioning of CD8+ effector T cells for adoptive cell therapy RI Klein Geltink, J Edwards-Hicks, P Apostolova, D O’Sullivan, DE Sanin, ... Nature metabolism 2 (8), 703-716, 2020 | 122 | 2020 |
| Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans FM Uhl, S Chen, D O’Sullivan, J Edwards-Hicks, G Richter, E Haring, ... Science translational medicine 12 (567), eabb8969, 2020 | 109 | 2020 |
| Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions AV Guitart, TI Panagopoulou, A Villacreces, M Vukovic, C Sepulveda, ... Journal of Experimental Medicine 214 (3), 719-735, 2017 | 83 | 2017 |
| An LKB1–mitochondria axis controls TH17 effector function F Baixauli, K Piletic, DJ Puleston, M Villa, CS Field, LJ Flachsmann, ... Nature 610 (7932), 555-561, 2022 | 55 | 2022 |
| Dynamic cardiolipin synthesis is required for CD8+ T cell immunity M Corrado, J Edwards-Hicks, M Villa, LJ Flachsmann, DE Sanin, ... Cell metabolism 32 (6), 981-995. e7, 2020 | 51 | 2020 |
| Plasmacytoid dendritic cell activation is dependent on coordinated expression of distinct amino acid transporters KM Grzes, DE Sanin, AM Kabat, MA Stanczak, J Edwards-Hicks, ... Immunity 54 (11), 2514-2530. e7, 2021 | 50 | 2021 |
| mTOR-regulated mitochondrial metabolism limits mycobacterium-induced cytotoxicity AJ Pagán, LJ Lee, J Edwards-Hicks, CB Moens, DM Tobin, ... Cell 185 (20), 3720-3738. e13, 2022 | 49 | 2022 |
| Fever supports CD8+ effector T cell responses by promoting mitochondrial translation D O’Sullivan, MA Stanczak, M Villa, FM Uhl, M Corrado, RI Klein Geltink, ... Proceedings of the National Academy of Sciences 118 (25), e2023752118, 2021 | 47 | 2021 |
| Intracellular infection and immune system cues rewire adipocytes to acquire immune function G Caputa, M Matsushita, DE Sanin, AM Kabat, J Edwards-Hicks, ... Cell metabolism 34 (5), 747-760. e6, 2022 | 38 | 2022 |
| Arachidonic acid inhibition of the NLRP3 inflammasome is a mechanism to explain the anti-inflammatory effects of fasting M Pereira, J Liang, J Edwards-Hicks, AM Meadows, C Hinz, S Liggi, ... Cell reports 43 (2), 2024 | 29 | 2024 |
| Sulfur sequestration promotes multicellularity during nutrient limitation B Kelly, GE Carrizo, J Edwards-Hicks, DE Sanin, MA Stanczak, ... Nature 591 (7850), 471-476, 2021 | 29 | 2021 |
| EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism S Ramamoorthy, K Kometani, JS Herman, M Bayer, S Boller, ... Genes & Development 34 (21-22), 1503-1519, 2020 | 29 | 2020 |
| AssayR: a simple mass spectrometry software tool for targeted metabolic and stable isotope tracer analyses J Wills, J Edwards-Hicks, AJ Finch Analytical chemistry 89 (18), 9616-9619, 2017 | 28 | 2017 |
| Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells P Altea-Manzano, A Vandekeere, J Edwards-Hicks, M Roldan, ... Molecular cell 82 (23), 4537-4547. e7, 2022 | 26 | 2022 |
| MYC sensitises cells to apoptosis by driving energetic demand J Edwards-Hicks, H Su, M Mangolini, KK Yoneten, J Wills, ... Nature communications 13 (1), 4674, 2022 | 24 | 2022 |
| Metabolic dynamics of in vitro CD8+ T cell activation J Edwards-Hicks, M Mitterer, EL Pearce, JM Buescher Metabolites 11 (1), 12, 2020 | 23 | 2020 |
