| Alternatives to antibiotics—a pipeline portfolio review L Czaplewski, R Bax, M Clokie, M Dawson, H Fairhead, VA Fischetti, ... The Lancet infectious diseases 16 (2), 239-251, 2016 | 979 | 2016 |
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity DJ Haydon, NR Stokes, R Ure, G Galbraith, JM Bennett, DR Brown, ... Science 321 (5896), 1673-1675, 2008 | 522 | 2008 |
| Discovery research: the scientific challenge of finding new antibiotics DM Livermore, ... Journal of antimicrobial chemotherapy 66 (9), 1941-1944, 2011 | 356 | 2011 |
| Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement I Chopra, C Schofield, M Everett, A O'Neill, K Miller, M Wilcox, JM Frère, ... The Lancet infectious diseases 8 (2), 133-139, 2008 | 351 | 2008 |
| Discovery and development of new antibacterial drugs: learning from experience? N Jackson, L Czaplewski, LJV Piddock Journal of Antimicrobial Chemotherapy 73 (6), 1452-1459, 2018 | 284 | 2018 |
| Analysis of the clinical antibacterial and antituberculosis pipeline U Theuretzbacher, S Gottwalt, P Beyer, M Butler, L Czaplewski, ... The Lancet Infectious Diseases 19 (2), e40-e50, 2019 | 251 | 2019 |
| Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1α, MIP-1β, and RANTES: characterization of active … LG Czaplewski, J McKeating, CJ Craven, LD Higgins, V Appay, A Brown, ... Journal of Biological Chemistry 274 (23), 16077-16084, 1999 | 220 | 1999 |
| Analysis of the clinical pipeline of treatments for drug-resistant bacterial infections: despite progress, more action is needed MS Butler, V Gigante, H Sati, S Paulin, L Al-Sulaiman, JH Rex, ... Antimicrobial agents and chemotherapy 66 (3), e01991-21, 2022 | 218 | 2022 |
| The urgent need for new antibacterial agents R Wise, ... Journal of antimicrobial chemotherapy 66 (9), 1939-1940, 2011 | 159 | 2011 |
| Mobilization of early hematopoietic progenitor cells with BB-10010: A genetically engineered variant of human macrophage inflammatory protein-la BI Lord, LB Woolford, LM Wood, LG Czaplewski, M McCourt, MG Hunter, ... Blood 85 (12), 3412-3415, 1995 | 156 | 1995 |
| The CC-chemokine RANTES increases the attachment of human immunodeficiency virus type 1 to target cells via glycosaminoglycans and also activates a signal transduction pathway … A Trkola, C Gordon, J Matthews, E Maxwell, T Ketas, L Czaplewski, ... Journal of virology 73 (8), 6370-6379, 1999 | 145 | 1999 |
| Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay NR Stokes, J Sievers, S Barker, JM Bennett, DR Brown, I Collins, ... Journal of Biological Chemistry 280 (48), 39709-39715, 2005 | 138 | 2005 |
| Creating an antibacterial with in vivo efficacy: synthesis and characterization of potent inhibitors of the bacterial cell division protein FtsZ with improved pharmaceutical … DJ Haydon, JM Bennett, D Brown, I Collins, G Galbraith, P Lancett, ... Journal of medicinal chemistry 53 (10), 3927-3936, 2010 | 129 | 2010 |
| Aggregation of RANTES is responsible for its inflammatory properties: characterization of nonaggregating, noninflammatory RANTES mutants V Appay, A Brown, S Cribbes, E Randle, LG Czaplewski Journal of Biological Chemistry 274 (39), 27505-27512, 1999 | 124 | 1999 |
| An Improved Small-Molecule Inhibitor of FtsZ with Superior In Vitro Potency, Drug-Like Properties, and In Vivo Efficacy NR Stokes, N Baker, JM Bennett, J Berry, I Collins, LG Czaplewski, ... Antimicrobial agents and chemotherapy 57 (1), 317-325, 2013 | 119 | 2013 |
| Purification and initial characterization of AhrC: the regulator of arginine metabolism genes in Bacillus subtilis LG Czaplewski, AK North, MCM Smith, S Baumberg, PG Stockley Molecular microbiology 6 (2), 267-275, 1992 | 114 | 1992 |
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ LG Czaplewski, I Collins, EA Boyd, D Brown, SP East, M Gardiner, ... Bioorganic & medicinal chemistry letters 19 (2), 524-527, 2009 | 113 | 2009 |
| RANTES activates antigen-specific cytotoxic T lymphocytes in a mitogen-like manner through cell surface aggregation V Appay, PR Dunbar, V Cerundolo, A McMichael, L Czaplewski, ... International immunology 12 (8), 1173-1182, 2000 | 109 | 2000 |
| Multiple effects of benzamide antibiotics on FtsZ function DW Adams, LJ Wu, LG Czaplewski, J Errington Molecular microbiology 80 (1), 68-84, 2011 | 107 | 2011 |
| Design, synthesis and structure–activity relationships of substituted oxazole–benzamide antibacterial inhibitors of FtsZ NR Stokes, N Baker, JM Bennett, PK Chauhan, I Collins, DT Davies, ... Bioorganic & medicinal chemistry letters 24 (1), 353-359, 2014 | 98 | 2014 |
