A platform of synthetic lethal gene interaction networks reveals that the GNAQ uveal melanoma oncogene controls the hippo pathway through FAK X Feng, N Arang, DC Rigiracciolo, JS Lee, H Yeerna, Z Wang, S Lubrano, ... Cancer cell 35 (3), 457-472. e5, 2019 | 231 | 2019 |
Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells M Vitiello, A Tuccoli, R D’Aurizio, S Sarti, L Giannecchini, S Lubrano, ... Oncotarget 8 (15), 25395, 2017 | 77 | 2017 |
Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma JS Paradis, M Acosta, R Saddawi-Konefka, A Kishore, S Lubrano, ... Clinical Cancer Research 27 (11), 3190-3200, 2021 | 69 | 2021 |
The landscape of BRAF transcript and protein variants in human cancer A Marranci, Z Jiang, M Vitiello, E Guzzolino, L Comelli, S Sarti, S Lubrano, ... Molecular Cancer 16, 1-25, 2017 | 37 | 2017 |
Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC) DC Rigiracciolo, N Nohata, R Lappano, F Cirillo, M Talia, ... Journal of Experimental & Clinical Cancer Research 41 (1), 193, 2022 | 35 | 2022 |
Identification of BRAF 3'UTR isoforms in melanoma A Marranci, A Tuccoli, M Vitiello, E Mercoledi, S Sarti, S Lubrano, ... The Journal of investigative dermatology 135 (6), 1694-1697, 2015 | 14 | 2015 |
Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ–focal adhesion kinase signaling circuitry N Arang, S Lubrano, DC Rigiracciolo, D Nachmanson, SM Lippman, ... Journal of Biological Chemistry 299 (2), 102866, 2023 | 13 | 2023 |
High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma N Arang, S Lubrano, M Ceribelli, DC Rigiracciolo, R Saddawi-Konefka, ... Cell Reports Medicine 4 (11), 2023 | 10 | 2023 |
Development of a yeast-based system to identify new hBRAFV600E functional interactors S Lubrano, L Comelli, C Piccirilli, A Marranci, F Dapporto, E Tantillo, ... Oncogene 38 (8), 1355-1366, 2019 | 10 | 2019 |
Early modifications of circulating microRNAs levels in metastatic colorectal cancer patients treated with regorafenib M Schirripa, B Borelli, R D’Aurizio, S Lubrano, C Cremolini, G Zucchelli, ... The Pharmacogenomics Journal 19 (5), 455-464, 2019 | 8 | 2019 |
Correction: Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma JS Paradis, M Acosta, R Saddawi-Konefka, A Kishore, S Lubrano, ... Clinical Cancer Research 27 (16), 4664-4664, 2021 | 2 | 2021 |
A novel combination therapy targeting RAF, MEK and FAK to overcome skin cutaneous melanoma treatment resistance S Lubrano, F Faraji, RD Cervantes-Villagrana, S Ramirez, N Arang, ... Cancer Research 84 (6_Supplement), 4745-4745, 2024 | 1 | 2024 |
Targeting FAK inhibits YAP-dependent tumor growth in uveal melanoma X Feng, D Rigiracciolo, JS Lee, H Yeerna, N Arang, S Lubrano, ... Cancer Research 78 (13_Supplement), 968-968, 2018 | 1 | 2018 |
Correction: The landscape of BRAF transcript and protein variants in human cancer A Marranci, Z Jiang, M Vitiello, E Guzzolino, L Comelli, S Sarti, S Lubrano, ... Molecular Cancer 24, 42, 2025 | | 2025 |
G alpha q controls the Hippo pathway through MOB1 tyrosine phosphorylation by FAK. X Feng, N Arang, DC Rigiracciolo, JS Lee, H Yeerna, Z Wang, S Lubrano, ... MOLECULAR CANCER RESEARCH 18 (8), 32-33, 2020 | | 2020 |
Abstract A20: Gαq controls the Hippo pathway through MOB1 tyrosine phosphorylation by FAK X Feng, N Arang, DC Rigiracciolo, JS Lee, H Yeerna, Z Wang, S Lubrano, ... Molecular Cancer Research 18 (8_Supplement), A20-A20, 2020 | | 2020 |
Yeast S. cerevisiae as a tool to study BRAFV600E kinase isoforms S Lubrano Università degli Studi di Siena, 2018 | | 2018 |
Role of the oncogenic BRAFV600E in the osmostress response of yeast Saccharomyces cerevisiae S Lubrano, L Comelli, A Galli, L Poliseno, T Cervelli YEAST 32, S183-S184, 2015 | | 2015 |
Identificazione di nuovi interattori funzionali di BRAFV600E tramite screening genetico in lievito Saccharomyces cerevisiae S LUBRANO | | 2014 |
ONCOGENOMICS UNIT L Poliseno, C Mattioli, M Vitiello, S Lubrano, US Elisa Mercoledi | | |