cGAS surveillance of micronuclei links genome instability to innate immunity KJ Mackenzie, P Carroll, CA Martin, O Murina, A Fluteau, DJ Simpson, ... Nature 548 (7668), 461-465, 2017 | 1585 | 2017 |
Chromatin architecture of the human genome: gene-rich domains are enriched in open chromatin fibers N Gilbert, S Boyle, H Fiegler, K Woodfine, NP Carter, WA Bickmore Cell 118 (5), 555-566, 2004 | 632 | 2004 |
Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination R Eskeland, M Leeb, GR Grimes, C Kress, S Boyle, D Sproul, N Gilbert, ... Molecular cell 38 (3), 452-464, 2010 | 623 | 2010 |
Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells M Jackson, A Krassowska, N Gilbert, T Chevassut, L Forrester, J Ansell, ... Molecular and cellular biology, 2004 | 418 | 2004 |
Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity A Serrels, T Lund, B Serrels, A Byron, RC McPherson, A von Kriegsheim, ... Cell 163 (1), 160-173, 2015 | 406 | 2015 |
Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures C Naughton, N Avlonitis, S Corless, JG Prendergast, IK Mati, PP Eijk, ... Nature structural & molecular biology 20 (3), 387-395, 2013 | 391 | 2013 |
The role of chromatin structure in regulating the expression of clustered genes D Sproul, N Gilbert, WA Bickmore Nature Reviews Genetics 6 (10), 775-781, 2005 | 352 | 2005 |
Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression T Latham, L Mackay, D Sproul, M Karim, J Culley, DJ Harrison, L Hayward, ... Nucleic Acids Research 40 (11), 4794-4803, 2012 | 336 | 2012 |
The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci RA Poot, L Bozhenok, DLC van den Berg, S Steffensen, F Ferreira, ... Nature cell biology 6 (12), 1236-1244, 2004 | 251 | 2004 |
SAF-A regulates interphase chromosome structure through oligomerization with chromatin-associated RNAs RS Nozawa, L Boteva, DC Soares, C Naughton, AR Dun, A Buckle, ... Cell 169 (7), 1214-1227. e18, 2017 | 217 | 2017 |
Chromatin organization in the mammalian nucleus N Gilbert, S Gilchrist, WA Bickmore International review of cytology 242, 283-336, 2005 | 198 | 2005 |
cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing C Uggenti, A Lepelley, M Depp, AP Badrock, MP Rodero, MT El-Daher, ... Nature Genetics 52 (12), 1364-1372, 2020 | 158 | 2020 |
Formation of facultative heterochromatin in the absence of HP1 N Gilbert, S Boyle, H Sutherland, J de Las Heras, J Allan, T Jenuwein, ... The EMBO journal, 2003 | 157 | 2003 |
Polymer simulations of heteromorphic chromatin predict the 3D folding of complex genomic loci A Buckle, CA Brackley, S Boyle, D Marenduzzo, N Gilbert Molecular cell 72 (4), 786-797. e11, 2018 | 153 | 2018 |
DNA methylation affects nuclear organization, histone modifications, and linker histone binding but not chromatin compaction N Gilbert, I Thomson, S Boyle, J Allan, B Ramsahoye, WA Bickmore The Journal of cell biology 177 (3), 401-411, 2007 | 153 | 2007 |
Supercoiling in DNA and chromatin N Gilbert, J Allan Current opinion in genetics & development 25, 15-21, 2014 | 151 | 2014 |
Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation GOM Bobkov, N Gilbert, P Heun Journal of Cell Biology 217 (6), 1957-1972, 2018 | 138 | 2018 |
Distinctive higher-order chromatin structure at mammalian centromeres N Gilbert, J Allan Proceedings of the National Academy of Sciences 98 (21), 11949-11954, 2001 | 132 | 2001 |
Effects of DNA supercoiling on chromatin architecture S Corless, N Gilbert Biophysical reviews 8 (3), 245-258, 2016 | 116 | 2016 |
Chromatin structure and evolution in the human genome JGD Prendergast, H Campbell, N Gilbert, MG Dunlop, WA Bickmore, ... BMC evolutionary biology 7, 1-12, 2007 | 96 | 2007 |