Switch in site of inhibition: a strategy for structure-based discovery of human topoisomerase IIα catalytic inhibitors AT Baviskar, SM Amrutkar, N Trivedi, V Chaudhary, A Nayak, SK Guchhait, ... ACS medicinal chemistry letters 6 (4), 481-485, 2015 | 102 | 2015 |
Imine/amide–imidazole conjugates derived from 5-amino-4-cyano-N1-substituted benzyl imidazole: Microwave-assisted synthesis and anticancer activity via … A Negi, JM Alex, SM Amrutkar, AT Baviskar, G Joshi, S Singh, ... Bioorganic & medicinal chemistry 23 (17), 5654-5661, 2015 | 57 | 2015 |
Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of topoisomerase IIα G Priyadarshani, S Amrutkar, A Nayak, UC Banerjee, CN Kundu, ... European Journal of Medicinal Chemistry 122, 43-54, 2016 | 49 | 2016 |
Scaffold-Hopping of Aurones: 2-Arylideneimidazo[1,2-a]pyridinones as Topoisomerase IIα-Inhibiting Anticancer Agents G Priyadarshani, A Nayak, SM Amrutkar, S Das, SK Guchhait, CN Kundu, ... ACS Medicinal Chemistry Letters 7 (12), 1056-1061, 2016 | 42 | 2016 |
Dual inhibitors of epidermal growth factor receptor and topoisomerase IIα derived from a quinoline scaffold M Chauhan, G Joshi, H Kler, A Kashyap, SM Amrutkar, P Sharma, ... RSC Advances 6 (81), 77717-77734, 2016 | 34 | 2016 |
E-pharmacophore guided discovery of pyrazolo [1, 5-c] quinazolines as dual inhibitors of topoisomerase-I and histone deacetylase G Joshi, S Kalra, UP Yadav, P Sharma, PK Singh, S Amrutkar, AJ Ansari, ... Bioorganic Chemistry 94, 103409, 2020 | 33 | 2020 |
Synthesis and biological evaluation of new 2, 5-dimethylthiophene/furan based N-acetyl pyrazolines as selective topoisomerase II inhibitors G Joshi, SM Amrutkar, AT Baviskar, H Kler, S Singh, UC Banerjee, ... RSC advances 6 (18), 14880-14892, 2016 | 30 | 2016 |
One-pot synthesis of (R)-1-(1-naphthyl) ethanol by stereoinversion using Candida parapsilosis SM Amrutkar, L Banoth, UC Banerjee Tetrahedron Letters 54 (25), 3274-3277, 2013 | 23 | 2013 |
Anticancer activity of dihydropyrazolo[1,5‐c]quinazolines against rat C6 glioma cells via inhibition of topoisomerase II G Kaur, RP Cholia, G Joshi, SM Amrutkar, S Kalra, AK Mantha, ... Archiv der Pharmazie 351 (6), 1800023, 2018 | 16 | 2018 |
Sulfinate based selective labelling of 5-hydroxy methylcytosine: Application to biotin pull down assay W Qiong, SM Amrutkar, F Shao Bioconjugate chemistry 29 (2), 245-249, 2018 | 12 | 2018 |
Chapter 3.TARGETING HUMAN TOPOISOMERASE-II: OPPORTUNITIES IN CANCER CHEMOTHERAPY SM Amrutkar, KD Bhilare Topoisomerase Inhibitors: Classification, Mechanisms of Action and Adverse …, 2017 | | 2017 |
Structure based design with modulation of known ligands leading to switch in mode of inhibition of human topoisomerase II alpha S Amrutkar, S Guchhait, U Banerjee ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
Dual inhibitors of epidermal growth factor receptor and topoisomerase IIa derived from a quinoline scaffold M Chauhan, G Joshi, H Kler, A Kashyap, SM Amrutkar, P Sharma, ... Royal Society of Chemistry, 2016 | | 2016 |
Establishment of a strategy," choice based change", in mode of inhibition: Development of imidazo [1, 2-a] pyridines/pyrazines as novel topoisomerase II alpha catalytic inhibitors S Amrutkar, S Guchhait, U Banerjee ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |