Signal transduction by vascular endothelial growth factor receptors S Koch, S Tugues, X Li, L Gualandi, L Claesson-Welsh Biochemical journal 437 (2), 169-183, 2011 | 1048 | 2011 |
HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF C Rolny, M Mazzone, S Tugues, D Laoui, I Johansson, C Coulon, ... Cancer cell 19 (1), 31-44, 2011 | 807 | 2011 |
New insights into IL-12-mediated tumor suppression S Tugues, SH Burkhard, I Ohs, M Vrohlings, K Nussbaum, J Vom Berg, ... Cell Death & Differentiation 22 (2), 237-246, 2015 | 621 | 2015 |
GM-CSF: from growth factor to central mediator of tissue inflammation B Becher, S Tugues, M Greter Immunity 45 (5), 963-973, 2016 | 599 | 2016 |
Single-cell mapping of human brain cancer reveals tumor-specific instruction of tissue-invading leukocytes E Friebel, K Kapolou, S Unger, NG Núñez, S Utz, EJ Rushing, L Regli, ... Cell 181 (7), 1626-1642. e20, 2020 | 524 | 2020 |
Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats S Tugues, G Fernandez‐Varo, J Muñoz‐Luque, J Ros, V Arroyo, J Rodés, ... Hepatology 46 (6), 1919-1926, 2007 | 320 | 2007 |
Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease S Van de Veire, I Stalmans, F Heindryckx, H Oura, A Tijeras-Raballand, ... Cell 141 (1), 178-190, 2010 | 309 | 2010 |
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells NR Mathew, F Baumgartner, L Braun, D O'Sullivan, S Thomas, ... Nature medicine 24 (3), 282-291, 2018 | 288 | 2018 |
Vascular endothelial growth factors and receptors: anti-angiogenic therapy in the treatment of cancer S Tugues, S Koch, L Gualandi, X Li, L Claesson-Welsh Molecular aspects of medicine 32 (2), 88-111, 2011 | 233 | 2011 |
Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma G Agliardi, AR Liuzzi, A Hotblack, D De Feo, N Núñez, CL Stowe, ... Nature communications 12 (1), 444, 2021 | 228 | 2021 |
Regression of fibrosis after chronic stimulation of cannabinoid CB2 receptor in cirrhotic rats J Muñoz-Luque, J Ros, G Fernández-Varo, S Tugues, M Morales-Ruiz, ... Journal of Pharmacology and Experimental Therapeutics 324 (2), 475-483, 2008 | 212 | 2008 |
Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic rats M Morales-Ruiz, P Cejudo-martı́n, G Fernández-Varo, S Tugues, J Ros, ... Gastroenterology 125 (2), 522-531, 2003 | 163 | 2003 |
Inhibition of placental growth factor activity reduces the severity of fibrosis, inflammation, and portal hypertension in cirrhotic mice C Van Steenkiste, J Ribera, A Geerts, M Pauta, S Tugues, C Casteleyn, ... Hepatology 53 (5), 1629-1640, 2011 | 104 | 2011 |
Conventional NK cells and tissue-resident ILC1s join forces to control liver metastasis L Ducimetière, G Lucchiari, G Litscher, M Nater, L Heeb, NG Nuñez, ... Proceedings of the National Academy of Sciences 118 (27), e2026271118, 2021 | 93 | 2021 |
Tissue microenvironment dictates the fate and tumor-suppressive function of type 3 ILCs K Nussbaum, SH Burkhard, I Ohs, F Mair, CSN Klose, SJ Arnold, ... Journal of Experimental Medicine 214 (8), 2331-2347, 2017 | 91 | 2017 |
Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF–licensed myeloid cells S Tugues, A Amorim, S Spath, G Martin-Blondel, B Schreiner, D De Feo, ... Science translational medicine 10 (469), eaat8410, 2018 | 89 | 2018 |
Tetraspanin CD63 promotes vascular endothelial growth factor receptor 2-β1 integrin complex formation, thereby regulating activation and downstream signaling in endothelial … S Tugues, S Honjo, C König, N Padhan, J Kroon, L Gualandi, X Li, ... Journal of Biological Chemistry 288 (26), 19060-19071, 2013 | 85 | 2013 |
Restoration of natural killer cell antimetastatic activity by IL12 and checkpoint blockade I Ohs, L Ducimetière, J Marinho, P Kulig, B Becher, S Tugues Cancer research 77 (24), 7059-7071, 2017 | 82 | 2017 |
CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer P Tallón de Lara, H Castañón, M Vermeer, N Núñez, K Silina, B Sobottka, ... Nature communications 12 (1), 769, 2021 | 78* | 2021 |
Increased nitric oxide production in lymphatic endothelial cells causes impairment of lymphatic drainage in cirrhotic rats J Ribera, M Pauta, P Melgar-Lesmes, S Tugues, G Fernández-Varo, ... Gut 62 (1), 138-145, 2013 | 62 | 2013 |