Pressure‐induced changes in the solution structure of the GB1 domain of protein G DJ Wilton, RB Tunnicliffe, YO Kamatari, K Akasaka, MP Williamson Proteins: Structure, Function, and Bioinformatics 71 (3), 1432-1440, 2008 | 67 | 2008 |
Structure of a mannan-specific family 35 carbohydrate-binding module: evidence for significant conformational changes upon ligand binding RB Tunnicliffe, DN Bolam, G Pell, HJ Gilbert, MP Williamson Journal of molecular biology 347 (2), 287-296, 2005 | 60 | 2005 |
Characterization of a double dockerin from the cellulosome of the anaerobic fungus Piromyces equi T Nagy, RB Tunnicliffe, LD Higgins, C Walters, HJ Gilbert, MP Williamson Journal of molecular biology 373 (3), 612-622, 2007 | 58 | 2007 |
Structural basis for the recognition of cellular mRNA export factor REF by herpes viral proteins HSV-1 ICP27 and HVS ORF57 RB Tunnicliffe, GM Hautbergue, P Kalra, BR Jackson, A Whitehouse, ... PLoS pathogens 7 (1), e1001244, 2011 | 56 | 2011 |
Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding H Troilo, AV Zuk, RB Tunnicliffe, AP Wohl, R Berry, RF Collins, TA Jowitt, ... Proceedings of the National Academy of Sciences 111 (36), 13063-13068, 2014 | 51 | 2014 |
The solution structure of the PufX polypeptide from Rhodobacter sphaeroides RB Tunnicliffe, EC Ratcliffe, CN Hunter, MP Williamson FEBS letters 580 (30), 6967-6971, 2006 | 48 | 2006 |
Signature active site architectures illuminate the molecular basis for ligand specificity in family 35 carbohydrate binding module MAS Correia, DW Abbott, TM Gloster, VO Fernandes, JAM Prates, ... Biochemistry 49 (29), 6193-6205, 2010 | 43 | 2010 |
Experimental evidence that the membrane-spanning helix of PufX adopts a bent conformation that facilitates dimerisation of the Rhodobacter sphaeroides RC–LH1 complex through N … EC Ratcliffe, RB Tunnicliffe, IW Ng, PG Adams, P Qian, K Holden-Dye, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1807 (1), 95-107, 2011 | 40 | 2011 |
Novel xylan-binding properties of an engineered family 4 carbohydrate-binding module L Cicortas Gunnarsson, C Montanier, RB Tunnicliffe, MP Williamson, ... Biochemical Journal 406 (2), 209-214, 2007 | 38 | 2007 |
An experimental investigation of conformational fluctuations in proteins G and L RB Tunnicliffe, JL Waby, RJ Williams, MP Williamson Structure 13 (11), 1677-1684, 2005 | 36 | 2005 |
The herpes viral transcription factor ICP4 forms a novel DNA recognition complex RB Tunnicliffe, MP Lockhart-Cairns, C Levy, AP Mould, TA Jowitt, H Sito, ... Nucleic acids research 45 (13), 8064-8078, 2017 | 32 | 2017 |
The structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer RB Tunnicliffe, M Schacht, C Levy, TA Jowitt, RM Sandri-Goldin, ... Scientific reports 5 (1), 11234, 2015 | 27 | 2015 |
Competitive and cooperative interactions mediate RNA transfer from herpesvirus saimiri ORF57 to the mammalian export adaptor ALYREF RB Tunnicliffe, GM Hautbergue, SA Wilson, P Kalra, AP Golovanov PLoS pathogens 10 (2), e1003907, 2014 | 25 | 2014 |
Molecular mechanism of SR protein kinase 1 inhibition by the herpes virus protein ICP27 RB Tunnicliffe, WK Hu, MY Wu, C Levy, AP Mould, EA McKenzie, ... MBio 10 (5), 10.1128/mbio. 02551-19, 2019 | 24 | 2019 |
Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway H Troilo, AL Barrett, AV Zuk, MP Lockhart-Cairns, AP Wohl, CP Bayley, ... Matrix Biology 55, 49-62, 2016 | 20 | 2016 |
Overlapping motifs on the herpes viral proteins ICP27 and ORF57 mediate interactions with the mRNA export adaptors ALYREF and UIF RB Tunnicliffe, X Tian, J Storer, RM Sandri-Goldin, AP Golovanov Scientific Reports 8, 15005, 2018 | 17 | 2018 |
The ICP27 homology domain of the human cytomegalovirus protein UL69 adopts a dimer-of-dimers structure RB Tunnicliffe, RF Collins, HD Ruiz Nivia, RM Sandri-Goldin, ... MBio 9 (3), 10.1128/mbio. 01112-18, 2018 | 13 | 2018 |
Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis MM Katariya, M Snee, RB Tunnicliffe, ME Kavanagh, HIM Boshoff, ... Chemistry–A European Journal 29 (29), e202203868, 2023 | 5 | 2023 |
A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening … M Frederickson, IR Selvam, D Evangelopoulos, KJ McLean, MM Katariya, ... European Journal of Medicinal Chemistry 230, 114105, 2022 | 5 | 2022 |
Structural identification of conserved RNA binding sites in herpesvirus ORF57 homologs: implications for PAN RNA recognition RB Tunnicliffe, C Levy, HD Ruiz Nivia, RM Sandri-Goldin, AP Golovanov Nucleic acids research 47 (4), 1987-2001, 2019 | 5 | 2019 |