TCR sequencing paired with massively parallel 3′ RNA-seq reveals clonotypic T cell signatures AA Tu, TM Gierahn, B Monian, DM Morgan, NK Mehta, B Ruiter, ... Nature immunology 20 (12), 1692-1699, 2019 | 130 | 2019 |
Lack of CD8+ T cell effector differentiation during priming mediates checkpoint blockade resistance in non–small cell lung cancer BL Horton, DM Morgan, N Momin, M Zagorulya, E Torres-Mejia, ... Science immunology 6 (64), eabi8800, 2021 | 114 | 2021 |
Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations TE Miller, CA Lareau, JA Verga, EAK DePasquale, V Liu, D Ssozi, ... Nature biotechnology 40 (7), 1030-1034, 2022 | 107 | 2022 |
Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity L Ma, A Hostetler, DM Morgan, L Maiorino, I Sulkaj, CA Whittaker, ... Cell 186 (15), 3148-3165. e20, 2023 | 92 | 2023 |
Clonally expanded, GPR15-expressing pathogenic effector TH2 cells are associated with eosinophilic esophagitis DM Morgan, B Ruiter, NP Smith, AA Tu, B Monian, BE Stone, ... Science immunology 6 (62), eabi5586, 2021 | 88 | 2021 |
Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer M Zagorulya, L Yim, DM Morgan, A Edwards, E Torres-Mejia, N Momin, ... Immunity 56 (2), 386-405. e10, 2023 | 83 | 2023 |
Peanut oral immunotherapy differentially suppresses clonally distinct subsets of T helper cells B Monian, AA Tu, B Ruiter, DM Morgan, PM Petrossian, NP Smith, ... The Journal of clinical investigation 132 (2), 2022 | 69 | 2022 |
Low protease activity in B cell follicles promotes retention of intact antigens after immunization A Aung, A Cui, L Maiorino, AP Amini, JR Gregory, M Bukenya, Y Zhang, ... Science 379 (6630), eabn8934, 2023 | 58 | 2023 |
Revealing the heterogeneity of CD4+ T cells through single-cell transcriptomics DM Morgan, WG Shreffler, JC Love Journal of Allergy and Clinical Immunology 150 (4), 748-755, 2022 | 11 | 2022 |
WAT3R: recovery of T-cell receptor variable regions from 3′ single-cell RNA-sequencing M Ainciburu, DM Morgan, EAK DePasquale, JC Love, F Prósper, ... Bioinformatics 38 (14), 3645-3647, 2022 | 10 | 2022 |
Identification of highly cross-reactive mimotopes for a public T cell response in murine melanoma BE Grace, CM Backlund, DM Morgan, BH Kang, NK Singh, BD Huisman, ... Frontiers in Immunology 13, 886683, 2022 | 10 | 2022 |
Expansion of tumor-reactive CD8+ T cell clonotypes occurs in the spleen in response to immune checkpoint blockade DM Morgan, BL Horton, V Bhandarkar, R Van, T Dinter, M Zagorulya, ... Science immunology 9 (99), eadi3487, 2024 | 6 | 2024 |
Interferon-γ signaling in eosinophilic esophagitis affects epithelial barrier function and programmed cell death. M Lal, CM Burk, R Gautam, Z Mrozek, KE Canziani, T Trachsel, J Beers, ... Cellular and Molecular Gastroenterology and Hepatology, 101466, 2025 | 3* | 2025 |
Full-length single-cell BCR sequencing paired with RNA sequencing reveals convergent responses to pneumococcal vaccination DM Morgan, YJ Zhang, JH Kim, MA Murillo, S Singh, J Loschko, ... Communications Biology 7 (1), 1208, 2024 | 2* | 2024 |
Vaccines combining slow delivery and follicle targeting of antigens increase germinal center B cell clonal diversity and clonal expansion KA Rodrigues, YJ Zhang, A Aung, DM Morgan, L Maiorino, P Yousefpour, ... bioRxiv, 2024 | 1 | 2024 |
Lung-cancer specific t cell dysfunction KD Wittrup, JC Love, S Spranger, B Horton, D Morgan US Patent App. 18/280,775, 2024 | 1 | 2024 |
Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells TM Grzywa, A Neeser, R Ramasubramanian, A Romanov, R Tannir, ... bioRxiv, 2024.04. 16.589780, 2024 | 1 | 2024 |
530 Antigen-dependent differentiation and expansion of tumor-infiltrating CD8+ T cell clonotypes occurs in the spleen in response to immune checkpoint blockade V Bhandarkar, B Horton, D Morgan, R Van, T Dinter, M Zagorulya, ... Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024 | | 2024 |
918 The signal strength of signal 2 and 3 during T cell priming affect the functional fate of an anti-tumor T cell response T Dinter, V Bhandarkar, D Morgan, L Pop, M Carney, EA Lutz, KD Wittrup, ... Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024 | | 2024 |
Percentage of peripheral blood GPR15+ pathogenic effector Th2 cells that are CD38 positive may identify active eosinophilic esophagitis C Burk, D Morgan, Y Virkud, E Liao, NV Hundal, A Katz, Q Yuan, ... Journal of Allergy and Clinical Immunology 153 (2), AB146, 2024 | | 2024 |