Prati
Ruth Densham
Ruth Densham
Potvrđena adresa e-pošte na bham.ac.uk
Naslov
Citirano
Citirano
Godina
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress
JR Morris, C Boutell, M Keppler, R Densham, D Weekes, A Alamshah, ...
Nature 462 (7275), 886-890, 2009
5392009
Human BRCA1–BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection
RM Densham, AJ Garvin, HR Stone, J Strachan, RA Baldock, ...
Nature structural & molecular biology 23 (7), 647-655, 2016
3062016
The proteasomal de‐ubiquitinating enzyme POH1 promotes the double‐strand DNA break response
LR Butler, RM Densham, J Jia, AJ Garvin, HR Stone, V Shah, D Weekes, ...
The EMBO journal 31 (19), 3918-3934, 2012
1662012
Isomerization of BRCA1–BARD1 promotes replication fork protection
M Daza-Martin, K Starowicz, M Jamshad, S Tye, GE Ronson, HL MacKay, ...
Nature 571 (7766), 521-527, 2019
1232019
The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair
AJ Garvin, RM Densham, SA Blair‐Reid, KM Pratt, HR Stone, D Weekes, ...
EMBO reports 14 (11), 975-983, 2013
1192013
ERK1/2 and p38 cooperate to induce a p21CIP1-dependent G1 cell cycle arrest
DE Todd, RM Densham, SA Molton, K Balmanno, C Newson, CR Weston, ...
Oncogene 23 (19), 3284-3295, 2004
1192004
MST kinases monitor actin cytoskeletal integrity and signal via c-Jun N-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability
RM Densham, E O'Neill, J Munro, I König, K Anderson, W Kolch, ...
Molecular and cellular biology, 2009
1012009
USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A
M Uckelmann, RM Densham, R Baas, HHK Winterwerp, A Fish, TK Sixma, ...
Nature communications 9 (1), 229, 2018
992018
The BRCA1 Ubiquitin ligase function sets a new trend for remodelling in DNA repair
RM Densham, JR Morris
Nucleus 8 (2), 116-125, 2017
582017
Stability of p21Waf1/Cip1 CDK inhibitor protein is responsive to RhoA-mediated regulation of the actin cytoskeleton
ML Coleman, RM Densham, DR Croft, MF Olson
Oncogene 25 (19), 2708-2716, 2006
532006
Moving mountains—the BRCA1 promotion of DNA resection
RM Densham, JR Morris
Frontiers in Molecular Biosciences 6, 79, 2019
512019
The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms
AJ Garvin, AK Walker, RM Densham, AS Chauhan, HR Stone, HL Mackay, ...
Genes & Development 33 (5-6), 333-347, 2019
472019
Discovery of peptide ligands targeting a specific ubiquitin-like domain–binding site in the deubiquitinase USP11
A Spiliotopoulos, LB Ferreras, RM Densham, SG Caulton, BC Maddison, ...
Journal of Biological Chemistry 294 (2), 424-436, 2019
362019
ERK1/2 and p38 cooperate to delay progression through G1 by promoting cyclin D1 protein turnover
RM Densham, DE Todd, K Balmanno, SJ Cook
Cellular Signalling 20 (11), 1986-1994, 2008
282008
Imaging nanoscale nuclear structures with expansion microscopy
EL Faulkner, JA Pike, RM Densham, E Garlick, SG Thomas, RK Neely, ...
Journal of Cell Science 135 (14), jcs259009, 2022
92022
BRCA1-BARD1: The importance of being in shape
M Daza-Martin, RM Densham, JR Morris
Molecular & Cellular Oncology 6 (6), e1656500, 2019
82019
New regulators of the BRCA1 response to genotoxic stress
JR Morris, C Boutell, M Keppler, R Densham, D Weekes, A Alamshah, ...
Breast Cancer Research 12, 1-1, 2010
22010
Disruption of pml nuclear bodies cooperates in the pathogenesis of acute promyelocytic leukemia
E Moravcsik, M Joannides, E Voisset, EW Stratford, BB Zeisig, J Morris, ...
Blood 122 (21), 3721, 2013
12013
USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication
HL Mackay, HR Stone, GE Ronson, K Ellis, A Lanz, Y Aghabi, AK Walker, ...
Nature Communications 15 (1), 8102, 2024
2024
SUMO4 promotes SUMO deconjugation required for DNA double-strand break repair
AJ Garvin, AJ Lanz, K Starowicz, GE Ronson, MJW Mackintosh, ...
bioRxiv, 2022.03. 23.485504, 2022
2022
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