Prati
Daniel J. Balick
Daniel J. Balick
Instructor at Harvard Medical School
Potvrđena adresa e-pošte na hms.harvard.edu
Naslov
Citirano
Citirano
Godina
Distribution of fixed beneficial mutations and the rate of adaptation in asexual populations
BH Good, IM Rouzine, DJ Balick, O Hallatschek, MM Desai
Proceedings of the National Academy of Sciences 109 (13), 4950-4955, 2012
2492012
No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans
R Do, D Balick, H Li, I Adzhubei, S Sunyaev, D Reich
Nature genetics 47 (2), 126-131, 2015
2132015
Estimating the selective effects of heterozygous protein-truncating variants from human exome data
CA Cassa, D Weghorn, DJ Balick, DM Jordan, D Nusinow, KE Samocha, ...
Nature genetics 49 (5), 806-810, 2017
1632017
Dynamic mutation–selection balance as an evolutionary attractor
S Goyal, DJ Balick, ER Jerison, RA Neher, BI Shraiman, MM Desai
Genetics 191 (4), 1309-1319, 2012
1242012
Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection
AP Schoech, DM Jordan, PR Loh, S Gazal, LJ O’Connor, DJ Balick, ...
Nature communications 10 (1), 790, 2019
1232019
The landscape of tolerated genetic variation in humans and primates
H Gao, T Hamp, J Ede, JG Schraiber, J McRae, M Singer-Berk, Y Yang, ...
Science 380 (6648), eabn8153, 2023
1002023
Dominance of deleterious alleles controls the response to a population bottleneck
DJ Balick, R Do, CA Cassa, D Reich, SR Sunyaev
PLoS genetics 11 (8), e1005436, 2015
852015
Applicability of the mutation–selection balance model to population genetics of heterozygous protein-truncating variants in humans
D Weghorn, DJ Balick, C Cassa, JA Kosmicki, MJ Daly, DR Beier, ...
Molecular Biology and Evolution 36 (8), 1701-1710, 2019
322019
Quantification of frequency-dependent genetic architectures and action of negative selection in 25 UK Biobank traits
AP Schoech, D Jordan, PR Loh, S Gazal, L O’Connor, DJ Balick, ...
BioRxiv, 188086, 2017
222017
Overcoming constraints on the detection of recessive selection in human genes from population frequency data
DJ Balick, DM Jordan, S Sunyaev, R Do
The American Journal of Human Genetics 109 (1), 33-49, 2022
152022
The rate of adaptation and the distribution of fixed beneficial mutations in asexual populations
BH Good, IM Rouzine, DJ Balick, O Hallatschek, MM Desai
Proceedings of the National Academy of Sciences 109, 4950-4955, 2012
82012
Response to a population bottleneck can be used to infer recessive selection
DJ Balick, R Do, D Reich, SR Sunyaev
arXiv preprint arXiv:1312.3028, 2013
72013
Quantification of frequency-dependent genetic architectures and action of negative selection in 25 UK Biobank traits. bioRxiv
A Schoech, D Jordan, PR Loh, S Gazal, L O’Connor, DJ Balick, ...
September, 2017
62017
Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy
DW Radke, JH Sul, DJ Balick, S Akle, RC Green, SR Sunyaev, ...
Genome Research 31 (6), 935-946, 2021
42021
Rare beneficial mutations can halt Muller's ratchet
S Goyal, DJ Balick, ER Jerison, RA Neher, BI Shraiman, MM Desai
arXiv preprint arXiv:1110.2939, 2011
42011
Probing the aggregated effects of purifying selection per individual on 1,380 medical phenotypes in the UK biobank
HMT Vy, DM Jordan, DJ Balick, R Do
PLoS Genetics 17 (1), e1009337, 2021
32021
Reply to ‘Selective effects of heterozygous protein-truncating variants’
CA Cassa, D Weghorn, DJ Balick, DM Jordan, D Nusinow, KE Samocha, ...
Nature genetics 51 (1), 3-4, 2019
32019
A field theoretic approach to non-equilibrium population genetics in the strong selection regime
DJ Balick
bioRxiv, 2023
22023
Rare beneficial mutations can halt Muller's ratchet
D Balick, S Goyal, E Jerison, R Neher, B Shraiman, M Desai
APS March Meeting Abstracts 2012, B51. 005, 2012
22012
Strength of purifying selection on the amino-acid sequence is associated with the amount of non-additive variance in gene expression
M Takou, DJ Balick, KA Steige, J Clo, H Dittberner, U Göbel, H Schielzeth, ...
bioRxiv, 2022.02. 11.480164, 2022
12022
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