Severe malarial anemia: innate immunity and pathogenesis DJ Perkins, T Were, GC Davenport, P Kempaiah, JB Hittner, JM Ong'echa International journal of biological sciences 7 (9), 1427, 2011 | 449 | 2011 |
Natural infection of Plasmodium brasilianum in humans: man and monkey share quartan malaria parasites in the Venezuelan Amazon A Lalremruata, M Magris, S Vivas-Martínez, M Koehler, M Esen, ... EBioMedicine 2 (9), 1186-1192, 2015 | 179 | 2015 |
Discovery of New Hydroxyethylamine Analogs against 3CLpro Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure–Activity Relationship … S Kumar, PP Sharma, U Shankar, D Kumar, SK Joshi, L Pena, ... J. Chem. Inf. Model, 2020 | 146 | 2020 |
Mycobacterium abscessus glycopeptidolipid prevents respiratory epithelial TLR2 signaling as measured by HβD2 gene expression and IL-8 release LB Davidson, R Nessar, P Kempaiah, DJ Perkins, TF Byrd PloS one 6 (12), e29148, 2011 | 82 | 2011 |
Mechanisms of erythropoiesis inhibition by malarial pigment and malaria‐induced proinflammatory mediators in an in vitro model GA Awandare, P Kempaiah, DO Ochiel, P Piazza, CC Keller, DJ Perkins American journal of hematology 86 (2), 155-162, 2011 | 74 | 2011 |
A review of the preclinical and clinical efficacy of remdesivir, hydroxychloroquine, and lopinavir-ritonavir treatments against COVID-19 D Maciorowski, SZE Idrissi, Y Gupta, BJ Medernach, MB Burns, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (10), 1108-1122, 2020 | 43 | 2020 |
Human tissue factor pathway inhibitor-2 induces caspase-mediated apoptosis in a human fibrosarcoma cell line P Kempaiah, W Kisiel Apoptosis 13, 702-715, 2008 | 43 | 2008 |
Fluorinated scaffolds for antimalarial drug discovery C Upadhyay, M Chaudhary, RN De Oliveira, A Borbas, P Kempaiah, P S, ... Expert Opinion on Drug Discovery 15 (6), 705-718, 2020 | 40 | 2020 |
Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues P Kempaiah, HS Chand, W Kisiel Molecular cancer 6, 1-11, 2007 | 39 | 2007 |
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays Y Gupta, D Maciorowski, SE Zak, KA Jones, RS Kathayat, SA Azizi, ... Methods 195, 57-71, 2021 | 37 | 2021 |
Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children C Ouma, GC Davenport, S Garcia, P Kempaiah, A Chaudhary, T Were, ... Human genetics 131, 289-299, 2012 | 37 | 2012 |
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics Y Gupta, OV Savytskyi, M Coban, A Venugopal, V Pleqi, CA Weber, ... Molecular Aspects of Medicine 91, 101151, 2023 | 36 | 2023 |
Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy Y Gupta, D Maciorowski, SE Zak, CV Kulkarni, AS Herbert, R Durvasula, ... International Journal of Biological Macromolecules 183, 203-212, 2021 | 33 | 2021 |
Iron dysregulation in COVID‐19 and reciprocal evolution of SARS‐CoV‐2: Natura nihil frustra facit Y Gupta, D Maciorowski, B Medernach, DP Becker, R Durvasula, ... Journal of Cellular Biochemistry, 2022 | 32 | 2022 |
A novel compound active against SARS-CoV-2 targeting uridylate-specific endoribonuclease (NendoU/NSP15): in silico and in vitro investigations S Kumar, Y Gupta, SE Zak, C Upadhyay, N Sharma, AS Herbert, ... RSC Medicinal Chemistry 12 (10), 1757-1764, 2021 | 30 | 2021 |
Antiplasmodial activity of hydroxyethylamine analogs: synthesis, biological activity and structure activity relationship of plasmepsin inhibitors AK Singh, V Rajendran, S Singh, P Kumar, Y Kumar, A Singh, W Miller, ... Bioorganic & medicinal chemistry 26 (13), 3837-3844, 2018 | 30 | 2018 |
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality SB Anyona, P Kempaiah, E Raballah, C Ouma, T Were, GC Davenport, ... Infection and immunity 79 (12), 4923-4932, 2011 | 25 | 2011 |
Reduced parasite burden in children with falciparum malaria and bacteremia coinfections: role of mediators of inflammation GC Davenport, JB Hittner, V Otieno, Z Karim, H Mukundan, PW Fenimore, ... Mediators of inflammation 2016 (1), 4286576, 2016 | 24 | 2016 |
Polymorphic variability in the 3'untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria JM Ong'echa, EO Raballah, PM Kempaiah, SB Anyona, T Were, ... BMC genetics 12, 1-9, 2011 | 23 | 2011 |
Oseltamivir analogs with potent anti-influenza virus activity S Kumar, S Goicoechea, S Kumar, CM Pearce, R Durvasula, P Kempaiah, ... Drug Discovery Today 25 (8), 1389-1402, 2020 | 22 | 2020 |