Lasso peptides: an intriguing class of bacterial natural products JD Hegemann, M Zimmermann, X Xie, MA Marahiel Accounts of chemical research 48 (7), 1909-1919, 2015 | 392 | 2015 |
Insights into the unique phosphorylation of the lasso peptide paeninodin S Zhu, JD Hegemann, CD Fage, M Zimmermann, X Xie, U Linne, ... Journal of Biological Chemistry 291 (26), 13662-13678, 2016 | 148 | 2016 |
Lasso peptides from proteobacteria: genome mining employing heterologous expression and mass spectrometry JD Hegemann, M Zimmermann, S Zhu, D Klug, MA Marahiel Peptide Science 100 (5), 527-542, 2013 | 138 | 2013 |
Fighting antibiotic resistance—strategies and (pre) clinical developments to find new antibacterials S Walesch, J Birkelbach, G Jézéquel, FPJ Haeckl, JD Hegemann, ... EMBO reports 24 (1), e56033, 2023 | 133 | 2023 |
Caulosegnins I–III: a highly diverse group of lasso peptides derived from a single biosynthetic gene cluster JD Hegemann, M Zimmermann, X Xie, MA Marahiel Journal of the American Chemical Society 135 (1), 210-222, 2013 | 118 | 2013 |
The astexin-1 lasso peptides: biosynthesis, stability, and structural studies M Zimmermann, JD Hegemann, X Xie, MA Marahiel Chemistry & biology 20 (4), 558-569, 2013 | 106 | 2013 |
Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides JD Hegemann, M De Simone, M Zimmermann, TA Knappe, X Xie, ... Journal of Medicinal Chemistry 57 (13), 5829-5834, 2014 | 97 | 2014 |
Xanthomonins I–III: A New Class of Lasso Peptides with a Seven‐Residue Macrolactam Ring JD Hegemann, M Zimmermann, S Zhu, H Steuber, K Harms, X Xie, ... Angewandte Chemie International Edition 53 (8), 2230-2234, 2014 | 90 | 2014 |
The PqqD homologous domain of the radical SAM enzyme ThnB is required for thioether bond formation during thurincin H maturation BM Wieckowski, JD Hegemann, A Mielcarek, L Boss, O Burghaus, ... FEBS letters 589 (15), 1802-1806, 2015 | 89 | 2015 |
The B1 protein guides the biosynthesis of a lasso peptide S Zhu, CD Fage, JD Hegemann, A Mielcarek, D Yan, U Linne, ... Scientific reports 6 (1), 1-12, 2016 | 73 | 2016 |
Enterobacter bugandensis: a novel enterobacterial species associated with severe clinical infection NB Pati, SP Doijad, T Schultze, GK Mannala, Y Yao, S Jaiswal, D Ryan, ... Scientific reports 8 (1), 5392, 2018 | 72 | 2018 |
Matters of class: coming of age of class III and IV lanthipeptides JD Hegemann, RD Süssmuth RSC Chemical Biology 1 (3), 110-127, 2020 | 70 | 2020 |
Light‐controlled tyrosine nitration of proteins T Long, L Liu, Y Tao, W Zhang, J Quan, J Zheng, JD Hegemann, ... Angewandte Chemie International Edition 60 (24), 13414-13422, 2021 | 64 | 2021 |
Factors governing the thermal stability of lasso peptides JD Hegemann ChemBioChem 21 (1-2), 7-18, 2020 | 62 | 2020 |
Characterization of caulonodin lasso peptides revealed unprecedented N-terminal residues and a precursor motif essential for peptide maturation M Zimmermann, JD Hegemann, X Xie, MA Marahiel Chemical Science 5 (10), 4032-4043, 2014 | 59 | 2014 |
Investigation of substrate recognition and biosynthesis in class IV lanthipeptide systems JD Hegemann, WA Van Der Donk Journal of the American Chemical Society 140 (17), 5743-5754, 2018 | 55 | 2018 |
Ion mobility–mass spectrometry of lasso peptides: signature of a rotaxane topology K Jeanne Dit Fouque, C Afonso, S Zirah, JD Hegemann, M Zimmermann, ... Analytical chemistry 87 (2), 1166-1172, 2015 | 55 | 2015 |
Current developments in antibiotic discovery: Global microbial diversity as a source for evolutionary optimized anti‐bacterials JD Hegemann, J Birkelbach, S Walesch, R Müller EMBO reports 24 (1), e56184, 2023 | 51 | 2023 |
The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II JD Hegemann, CD Fage, S Zhu, K Harms, FS Di Leva, E Novellino, ... Molecular BioSystems 12 (4), 1106-1109, 2016 | 42 | 2016 |
Assessing the flexibility of the prochlorosin 2.8 scaffold for bioengineering applications JD Hegemann, SC Bobeica, MC Walker, IR Bothwell, WA Van Der Donk ACS synthetic biology 8 (5), 1204-1214, 2019 | 41 | 2019 |