Highly resistant HIV-1 proteases and strategies for their inhibition IT Weber, DW Kneller, A Wong-Sam Future medicinal chemistry 7 (8), 1023-1038, 2015 | 83 | 2015 |
Drug Resistance Mutation L76V Alters Nonpolar Interactions at the Flap–Core Interface of HIV-1 Protease A Wong-Sam, YF Wang, Y Zhang, AK Ghosh, RW Harrison, IT Weber ACS omega 3 (9), 12132-12140, 2018 | 26 | 2018 |
Structural studies of antiviral inhibitor with HIV-1 protease bearing drug resistant substitutions of V32I, I47V and V82I S Pawar, YF Wang, A Wong-Sam, J Agniswamy, AK Ghosh, RW Harrison, ... Biochemical and biophysical research communications 514 (3), 974-978, 2019 | 20 | 2019 |
HIV-1 protease with 10 lopinavir and darunavir resistance mutations exhibits altered inhibition, structural rearrangements and extreme dynamics A Wong-Sam, YF Wang, DW Kneller, AY Kovalevsky, AK Ghosh, ... Journal of Molecular Graphics and Modelling, 108315, 2022 | 3 | 2022 |
Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological … AK Ghosh, JL Mishevich, S Kovela, R Shaktah, AK Ghosh, M Johnson, ... European Journal of Medicinal Chemistry, 115385, 2023 | 2 | 2023 |
Structural & Enzymatic Studies on HIV-1 Protease Drug Resistance: Mutation L76V & Combination with Additional Resistance Mutations A Wong-Sam | | 2019 |