Role of inflammasome genetics in susceptibility to HPV infection and cervical cancer development A Pontillo, P Bricher, VNC Leal, S Lima, PRE Souza, S Crovella Journal of medical virology 88 (9), 1646-1651, 2016 | 80 | 2016 |
Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes AS Reis, R Barboza, O Murillo, A Barateiro, EPM Peixoto, FA Lima, ... Science Advances 6 (10), eaax6346, 2020 | 55 | 2020 |
Inflammasome genetics and complex diseases: a comprehensive review FP Fernandes, VNC Leal, D Souza de Lima, EC Reis, A Pontillo European Journal of Human Genetics 28 (10), 1307-1321, 2020 | 39 | 2020 |
Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid MR Davanso, AR Crisma, TT Braga, LN Masi, CL do Amaral, VNC Leal, ... Clinical Science 135 (1), 19-34, 2021 | 37 | 2021 |
Flagellin/NLRC4 pathway rescues NLRP3-inflammasome defect in dendritic cells from HIV-infected patients: perspective for new adjuvant in immunocompromised individuals EC Reis, VNC Leal, JLS Soares, FP Fernandes, D Souza de Lima, ... Frontiers in immunology 10, 1291, 2019 | 34 | 2019 |
Inflammasome in HIV infection: lights and shadows VNC Leal, EC Reis, A Pontillo Molecular immunology 118, 9-18, 2020 | 32 | 2020 |
Polymorphisms in inflammasome genes and risk of asthma in Brazilian children VNC Leal, IR Genov, MC Mallozi, D Solé, A Pontillo Molecular Immunology 93, 64-67, 2018 | 32 | 2018 |
Resveratrol downmodulates neutrophil extracellular trap (NET) generation by neutrophils in patients with severe COVID-19 MM de Souza Andrade, VNC Leal, IG Fernandes, SC Gozzi-Silva, ... Antioxidants 11 (9), 1690, 2022 | 21 | 2022 |
Double-edged sword of inflammasome genetics in colorectal cancer prognosis RAG Cambui, GF do Espirito Santo, FP Fernandes, VNC Leal, BB Galera, ... Clinical Immunology 213, 108373, 2020 | 19 | 2020 |
Antagonistic role of IL-1ß and NLRP3/IL-18 genetics in chronic HIV-1 infection EC Reis, VNC Leal, LT da Silva, MML Dos Reis, ER Arganaraz, ... Clinical Immunology 209, 108266, 2019 | 18 | 2019 |
Severe COVID‐19 patients show a dysregulation of the NLRP3 inflammasome in circulating neutrophils VNC Leal, MMS Andrade, FME Teixeira, RAG Cambui, MEGV Roa, ... Scandinavian journal of immunology 97 (3), e13247, 2023 | 15 | 2023 |
Common pathogen-associated molecular patterns induce the hyper-activation of NLRP3 inflammasome in circulating B lymphocytes of HIV-infected individuals VNC Leal, EC Reis, FP Fernandes, JL da Silva Soares, IGC Oliveira, ... AIDS 35 (6), 899-910, 2021 | 15 | 2021 |
Combining host genetics and functional analysis to depict inflammasome contribution in tuberculosis susceptibility and outcome in endemic areas D Souza De Lima, CCB Bomfim, VNC Leal, EC Reis, JLS Soares, ... Frontiers in Immunology 11, 550624, 2020 | 12 | 2020 |
The Ala134Thr variant in TMEM176B exerts a beneficial role in colorectal cancer prognosis by increasing NLRP3 inflammasome activation RAG Cambui, FP Fernandes, VNC Leal, EC Reis, DS de Lima, ... Journal of Cancer Research and Clinical Oncology 149 (7), 3729-3738, 2023 | 11 | 2023 |
Genetic contribution and functional impairment of inflammasome in sickle cell disease V de Freitas Dutra, VNC Leal, FP Fernandes, CRL Souza, MS Figueiredo, ... Cytokine 149, 155717, 2022 | 9 | 2022 |
A common variant close to the “tripwire” linker region of NLRP1 contributes to severe COVID-19 VNC Leal, LM Paulino, RAG Cambui, TG Zupelli, SM Yamada, ... Inflammation Research 72 (10), 1933-1940, 2023 | 8 | 2023 |
Gain-of-function SNPs in NLRP3 and IL1B genes confer protection against obesity and T2D: undiscovered role of inflammasome genetics in metabolic homeostasis? J de Moraes Rodrigues, D Souza de Lima, VNC Leal, AA Bosco, ... Endocrine 60, 368-371, 2018 | 7 | 2018 |
Canonical Inflammasomes VNC Leal, A Pontillo NLR Proteins: Methods and Protocols, 1-27, 2023 | 5 | 2023 |
Cervical carcinoma induces NLRP3 inflammasome activation and IL-1ß release in human peripheral blood monocytes affecting patients’ overall survival FP Fernandes, RAG Cambui, JLS Soares, EC Reis, VNC Leal, A Pontillo Clinical and Translational Oncology 25 (11), 3277-3286, 2023 | 3 | 2023 |
The inflammasomes: crosstalk between innate immunity and hematology V de Freitas Dutra, VNC Leal, A Pontillo Inflammation Research 71 (12), 1403-1416, 2022 | 3 | 2022 |