| Short-term in vivo exposure to the water contaminant triclosan: evidence for disruption of thyroxine KM Crofton, KB Paul, MJ DeVito, JM Hedge Environmental toxicology and pharmacology 24 (2), 194-197, 2007 | 309 | 2007 |
| The next generation blueprint of computational toxicology at the US Environmental Protection Agency RS Thomas, T Bahadori, TJ Buckley, J Cowden, C Deisenroth, ... Toxicological Sciences 169 (2), 317-332, 2019 | 305 | 2019 |
| Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization K Paul Friedman, M Gagne, LH Loo, P Karamertzanis, T Netzeva, ... Toxicological Sciences 173 (1), 202-225, 2020 | 194 | 2020 |
| Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches PD Noyes, KP Friedman, P Browne, JT Haselman, ME Gilbert, ... Environmental health perspectives 127 (9), 095001, 2019 | 166 | 2019 |
| Short-term Exposure to Triclosan Decreases Thyroxine In Vivo via Upregulation of Hepatic Catabolism in Young Long-Evans Rats KB Paul, JM Hedge, MJ DeVito, KM Crofton Toxicological Sciences 113 (2), 367-379, 2010 | 159 | 2010 |
| Tiered high-throughput screening approach to identify thyroperoxidase inhibitors within the ToxCast phase I and II chemical libraries K Paul Friedman, ED Watt, MW Hornung, JM Hedge, RS Judson, ... Toxicological Sciences 151 (1), 160-180, 2016 | 135 | 2016 |
| Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: a dynamic and kinetic evaluation of a putative mode-of-action KB Paul, JM Hedge, R Bansal, RT Zoeller, R Peter, MJ DeVito, ... Toxicology 300 (1-2), 31-45, 2012 | 135 | 2012 |
| Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling J Nyffeler, C Willis, R Lougee, A Richard, K Paul-Friedman, JA Harrill Toxicology and applied pharmacology 389, 114876, 2020 | 109 | 2020 |
| Development of a thyroperoxidase inhibition assay for high-throughput screening KB Paul, JM Hedge, DM Rotroff, MW Hornung, KM Crofton, SO Simmons Chemical research in toxicology 27 (3), 387-399, 2014 | 107 | 2014 |
| Developmental triclosan exposure decreases maternal and neonatal thyroxine in rats KB Paul, JM Hedge, MJ DeVito, KM Crofton Environmental Toxicology and Chemistry 29 (12), 2840-2844, 2010 | 95 | 2010 |
| ToxRefDB version 2.0: Improved utility for predictive and retrospective toxicology analyses S Watford, LL Pham, J Wignall, R Shin, MT Martin, KP Friedman Reproductive toxicology 89, 145-158, 2019 | 85 | 2019 |
| In Vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis NC Kleinstreuer, DJ Dix, KA Houck, RJ Kavlock, TB Knudsen, MT Martin, ... toxicological sciences 131 (1), 40-55, 2013 | 85 | 2013 |
| Limited chemical structural diversity found to modulate thyroid hormone receptor in the Tox21 chemical library K Paul-Friedman, M Martin, KM Crofton, CW Hsu, S Sakamuru, J Zhao, ... Environmental health perspectives 127 (9), 097009, 2019 | 67 | 2019 |
| High-throughput H295R steroidogenesis assay: utility as an alternative and a statistical approach to characterize effects on steroidogenesis DE Haggard, AL Karmaus, MT Martin, RS Judson, RW Setzer, ... Toxicological Sciences 162 (2), 509-534, 2018 | 55 | 2018 |
| Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors KB Paul, JT Thompson, SO Simmons, JPV Heuvel, KM Crofton Toxicology in vitro 27 (7), 2049-2060, 2013 | 54 | 2013 |
| Variability in in vivo studies: Defining the upper limit of performance for predictions of systemic effect levels LL Pham, SM Watford, P Pradeep, MT Martin, RS Thomas, RS Judson, ... Computational Toxicology 15, 100126, 2020 | 53 | 2020 |
| An exposure: activity profiling method for interpreting high-throughput screening data for estrogenic activity—Proof of concept RA Becker, KP Friedman, TW Simon, MS Marty, G Patlewicz, ... Regulatory Toxicology and Pharmacology 71 (3), 398-408, 2015 | 52 | 2015 |
| Evaluation of chemical effects on network formation in cortical neurons grown on microelectrode arrays TJ Shafer, JP Brown, B Lynch, S Davila-Montero, K Wallace, KP Friedman Toxicological Sciences 169 (2), 436-455, 2019 | 50 | 2019 |
| Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat KB Paul, JM Hedge, C Macherla, DL Filer, E Burgess, SO Simmons, ... Toxicology 312, 97-107, 2013 | 49 | 2013 |
| A predictive data-driven framework for endocrine prioritization: a triazole fungicide case study K Paul Friedman, S Papineni, MS Marty, KD Yi, AK Goetz, RJ Rasoulpour, ... Critical Reviews in Toxicology 46 (9), 785-833, 2016 | 39 | 2016 |
Richard JudsonUS EPA, Center for Computational Toxicology and ExposureE-mail megerősítve itt: epa.gov