| Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA L Warren, PD Manos, T Ahfeldt, YH Loh, H Li, F Lau, W Ebina, PK Mandal, ... Cell stem cell 7 (5), 618-630, 2010 | 3483 | 2010 |
| Disease-specific induced pluripotent stem cells IH Park, N Arora, H Huo, N Maherali, T Ahfeldt, A Shimamura, MW Lensch, ... cell 134 (5), 877-886, 2008 | 2836 | 2008 |
| From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus K Musunuru, A Strong, M Frank-Kamenetsky, NE Lee, T Ahfeldt, KV Sachs, ... Nature 466 (7307), 714-719, 2010 | 1294 | 2010 |
| A high-efficiency system for the generation and study of human induced pluripotent stem cells N Maherali, T Ahfeldt, A Rigamonti, J Utikal, C Cowan, K Hochedlinger Cell stem cell 3 (3), 340-345, 2008 | 761 | 2008 |
| A TALEN genome-editing system for generating human stem cell-based disease models Q Ding, YK Lee, EAK Schaefer, DT Peters, A Veres, K Kim, ... Cell stem cell 12 (2), 238-251, 2013 | 720 | 2013 |
| Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells S Eminli, A Foudi, M Stadtfeld, N Maherali, T Ahfeldt, G Mostoslavsky, ... Nature genetics 41 (9), 968-976, 2009 | 555 | 2009 |
| Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs H Mou, R Zhao, R Sherwood, T Ahfeldt, A Lapey, J Wain, L Sicilian, ... Cell stem cell 10 (4), 385-397, 2012 | 389 | 2012 |
| Programming human pluripotent stem cells into white and brown adipocytes T Ahfeldt, RT Schinzel, YK Lee, D Hendrickson, A Kaplan, DH Lum, ... Nature cell biology 14 (2), 209-219, 2012 | 288 | 2012 |
| Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities JM Madison, F Zhou, A Nigam, A Hussain, DD Barker, R Nehme, ... Molecular psychiatry 20 (6), 703-717, 2015 | 192 | 2015 |
| Dynamics of PARKIN-dependent mitochondrial ubiquitylation in induced neurons and model systems revealed by digital snapshot proteomics A Ordureau, JA Paulo, W Zhang, T Ahfeldt, J Zhang, EF Cohn, Z Hou, ... Molecular cell 70 (2), 211-227. e8, 2018 | 173 | 2018 |
| A reference human induced pluripotent stem cell line for large-scale collaborative studies CB Pantazis, A Yang, E Lara, JA McDonough, C Blauwendraat, L Peng, ... Cell stem cell 29 (12), 1685-1702. e22, 2022 | 133 | 2022 |
| Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy A Ordureau, F Kraus, J Zhang, H An, S Park, T Ahfeldt, JA Paulo, ... Molecular cell 81 (24), 5082-5098. e11, 2021 | 75 | 2021 |
| Pathogenic pathways in early-onset autosomal recessive Parkinson's disease discovered using isogenic human dopaminergic neurons T Ahfeldt, A Ordureau, C Bell, L Sarrafha, C Sun, S Piccinotti, T Grass, ... Stem cell reports 14 (1), 75-90, 2020 | 66 | 2020 |
| A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides KC Paul, RC Krolewski, E Lucumi Moreno, J Blank, KM Holton, T Ahfeldt, ... Nature communications 14 (1), 2803, 2023 | 46 | 2023 |
| Modeling the complex genetic architectures of brain disease MB Fernando, T Ahfeldt, KJ Brennand Nature genetics 52 (4), 363-369, 2020 | 44 | 2020 |
| Efficient culturing and genetic manipulation of human pluripotent stem cells RT Schinzel, T Ahfeldt, FH Lau, YK Lee, A Cowley, T Shen, D Peters, ... PLoS One 6 (12), e27495, 2011 | 35 | 2011 |
| Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson’s disease Q Wang, M Wang, I Choi, L Sarrafha, M Liang, L Ho, K Farrell, ... Science advances 10 (2), eadi8287, 2024 | 30 | 2024 |
| Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells E Navarro, E Udine, KP Lopes, M Parks, G Riboldi, BM Schilder, ... Nature aging 1 (9), 850-863, 2021 | 29 | 2021 |
| High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells L Sarrafha, GM Parfitt, R Reyes, C Goldman, E Coccia, T Kareva, ... STAR protocols 2 (2), 100463, 2021 | 21 | 2021 |
| Studying human disease using human neurons T Ahfeldt, NK Litterman, LL Rubin Brain research 1656, 40-48, 2017 | 19 | 2017 |
