| Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes R García-Navas, M Munder, F Mollinedo Autophagy 8 (11), 1557-1576, 2012 | 95 | 2012 |
| Mycobacterium tuberculosis transporter MmpL7 is a potential substrate for kinase PknD J Pérez, R Garcia, H Bach, JH de Waard, WR Jacobs Jr, Y Av-Gay, ... Biochemical and biophysical research communications 348 (1), 6-12, 2006 | 85 | 2006 |
| Endowing indole-based tubulin inhibitors with an anchor for derivatization: highly potent 3-substituted indolephenstatins and indoleisocombretastatins R Alvarez, P Puebla, JF Diaz, AC Bento, R Garcia-Navas, ... Journal of medicinal chemistry 56 (7), 2813-2827, 2013 | 80 | 2013 |
| Sos1 disruption impairs cellular proliferation and viability through an increase in mitochondrial oxidative stress in primary MEFs P Liceras-Boillos, R García-Navas, A Ginel-Picardo, B Anta, ... Oncogene 35 (50), 6389-6402, 2016 | 45 | 2016 |
| The metalloprotease ADAM8 is associated with and regulates the function of the adhesion receptor PSGL‐1 through ERM proteins M Domínguez‐Luis, A Lamana, J Vazquez, R García‐Navas, F Mollinedo, ... European journal of immunology 41 (12), 3436-3442, 2011 | 44 | 2011 |
| Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release R García-Navas, C Gajate, F Mollinedo Scientific reports 11 (1), 12574, 2021 | 34 | 2021 |
| Antitumor activity of new hydridotris (pyrazolyl) borate ruthenium (ii) complexes containing the phosphanes PTA and 1-CH 3–PTA A García-Fernández, J Díez, A Manteca, J Sánchez, R García-Navas, ... Dalton Transactions 39 (42), 10186-10196, 2010 | 34 | 2010 |
| Differential role of the RasGEFs Sos1 and Sos2 in mouse skin homeostasis and carcinogenesis P Liceras-Boillos, D Jimeno, R García-Navas, LF Lorenzo-Martín, ... Molecular and cellular biology 38 (16), e00049-18, 2018 | 27 | 2018 |
| SOS2 comes to the fore: differential functionalities in physiology and pathology FC Baltanás, R García-Navas, E Santos International Journal of Molecular Sciences 22 (12), 6613, 2021 | 25 | 2021 |
| Antitumor activity of new enantiopure pybox-ruthenium complexes E Menéndez-Pedregal, J Díez, Á Manteca, J Sánchez, AC Bento, ... Dalton Transactions 42 (38), 13955-13967, 2013 | 21 | 2013 |
| Critical requirement of SOS1 RAS-GEF function for mitochondrial dynamics, metabolism, and redox homeostasis R García-Navas, P Liceras-Boillos, C Gómez, FC Baltanás, N Calzada, ... Oncogene 40 (27), 4538-4551, 2021 | 20 | 2021 |
| Functional specificity of the members of the Sos family of Ras-GEF activators: novel role of Sos2 in control of epidermal stem cell homeostasis FC Baltanás, C Mucientes-Valdivieso, LF Lorenzo-Martín, ... Cancers 13 (9), 2152, 2021 | 10 | 2021 |
| Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma FC Baltanás, R García-Navas, P Rodríguez-Ramos, N Calzada, C Cuesta, ... Nature Communications 14 (1), 5856, 2023 | 9 | 2023 |
| Ras-GRF2 regulates nestin-positive stem cell density and onset of differentiation during adult neurogenesis in the mouse dentate gyrus C Gómez, D Jimeno, A Fernández-Medarde, R García-Navas, N Calzada, ... Molecular and Cellular Neuroscience 85, 127-147, 2017 | 9 | 2017 |
| Arginase as a new concern in blood transfusion F Mollinedo, MA Palomero-Rodríguez, P Sánchez-Conde, ... Blood Transfusion 12 (Suppl 1), s165, 2014 | 9 | 2014 |
| Critical requirement of SOS1 for development of BCR/ABL-driven chronic myelogenous leukemia C Gómez, R Garcia-Navas, FC Baltanás, R Fuentes-Mateos, ... Cancers 14 (16), 3893, 2022 | 8 | 2022 |
| Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors L Clavaín, I Fernández-Pisonero, N Movilla, LF Lorenzo-Martín, B Nieto, ... Oncogene 42 (5), 389-405, 2023 | 7 | 2023 |
| Anthraquinones as inhibitors of SOS RAS-GEF activity A Fernández-Medarde, R Fuentes-Mateos, R García-Navas, AOS Juan, ... Biomolecules 11 (8), 1128, 2021 | 6 | 2021 |
| Pharmacological SOS1 inhibitor BI-3406 demonstrates in vivo anti-tumor activity comparable to SOS1 genetic ablation in KRAS mutant tumors FC Baltanas, M Kramer-Drauberg, R Garcia-Navas, E Patrucco, E Petrini, ... bioRxiv, 2024.09. 18.613686, 2024 | 2 | 2024 |
| Sos1 disruption increases mitochondrial oxidative stress in primary MEFs R García-Navas, P Liceras-Boillos, B Anta, C Lillo, C Gómez, D Jimeno, ... European Journal of Cancer 61, S167, 2016 | 1 | 2016 |