In vitro and in vivo experimental models for drug screening and development for Chagas disease AJ Romanha, SL Castro, MNC Soeiro, J Lannes-Vieira, I Ribeiro, ... Memórias do Instituto Oswaldo Cruz 105, 233-238, 2010 | 398 | 2010 |
Fexinidazole: a potential new drug candidate for Chagas disease MT Bahia, IM Andrade, TAF Martins, ÁFS Nascimento, LF Diniz, IS Caldas, ... PLoS neglected tropical diseases 6 (11), e1870, 2012 | 202 | 2012 |
Chemotherapy with Benznidazole and Itraconazole for Mice Infected with Different Trypanosoma cruzi Clonal Genotypes MJO Toledo, MT Bahia, CM Carneiro, OA Martins-Filho, M Tibayrenc, ... Antimicrobial agents and chemotherapy 47 (1), 223-230, 2003 | 192 | 2003 |
Benznidazole and posaconazole in experimental Chagas disease: positive interaction in concomitant and sequential treatments LF Diniz, JA Urbina, IM de Andrade, AL Mazzeti, TAF Martins, IS Caldas, ... PLoS neglected tropical diseases 7 (8), e2367, 2013 | 146 | 2013 |
A comparative study of the TF-Test®, Kato-Katz, Hoffman-Pons-Janer, Willis and Baermann-Moraes coprologic methods for the detection of human parasitosis GLX Carvalho, LE Moreira, JL Pena, CC Marinho, MT Bahia, ... Memórias do Instituto Oswaldo Cruz 107, 80-84, 2012 | 115 | 2012 |
Activity of the New Triazole Derivative Albaconazole against Trypanosoma (Schizotrypanum) cruzi in Dog Hosts PMM Guedes, JA Urbina, M de Lana, LCC Afonso, VM Veloso, WL Tafuri, ... Antimicrobial Agents and Chemotherapy 48 (11), 4286-4292, 2004 | 111 | 2004 |
The dog as model for chemotherapy of the Chagas’ disease PM da Matta Guedes, VM Veloso, WL Tafuri, LM da Cunha Galvao, ... Acta tropica 84 (1), 9-17, 2002 | 110 | 2002 |
Effects of Ravuconazole Treatment on Parasite Load and Immune Response in Dogs Experimentally Infected with Trypanosoma cruzi LF Diniz, IS Caldas, PMM Guedes, G Crepalde, M de Lana, CM Carneiro, ... Antimicrobial agents and chemotherapy 54 (7), 2979-2986, 2010 | 107 | 2010 |
Benznidazole therapy during acute phase of Chagas disease reduces parasite load but does not prevent chronic cardiac lesions IS Caldas, A Talvani, S Caldas, CM Carneiro, M de Lana, ... Parasitology research 103, 413-421, 2008 | 104 | 2008 |
Interferon-γ-induced nitric oxide causes intrinsic intestinal denervation in Trypanosoma cruzi-infected mice RME Arantes, HHF Marche, MT Bahia, FQ Cunha, MA Rossi, JS Silva The American journal of pathology 164 (4), 1361-1368, 2004 | 104 | 2004 |
Therapeutical approaches under investigation for treatment of Chagas disease MT Bahia, LF Diniz, VCF Mosqueira Expert opinion on investigational drugs 23 (9), 1225-1237, 2014 | 96 | 2014 |
Development of chronic cardiomyopathy in canine Chagas disease correlates with high IFN-γ, TNF-α, and low IL-10 production during the acute infection phase PMM Guedes, VM Veloso, LCC Afonso, MV Caliari, CM Carneiro, ... Veterinary immunology and immunopathology 130 (1-2), 43-52, 2009 | 92 | 2009 |
Antitrypanosomal activity of fexinidazole metabolites, potential new drug candidates for Chagas disease MT Bahia, AFS Nascimento, AL Mazzeti, LF Marques, KR Gonçalves, ... Antimicrobial agents and chemotherapy 58 (8), 4362-4370, 2014 | 90 | 2014 |
Influence of Ecto-Nucleoside Triphosphate Diphosphohydrolase Activity on Trypanosoma cruzi Infectivity and Virulence RF Santos, MAS Pôssa, MS Bastos, PMM Guedes, MR Almeida, ... PLoS neglected tropical diseases 3 (3), e387, 2009 | 90 | 2009 |
Real-time PCR strategy for parasite quantification in blood and tissue samples of experimental Trypanosoma cruzi infection S Caldas, IS Caldas, L de Figueiredo Diniz, WG de Lima, ... Acta tropica 123 (3), 170-177, 2012 | 86 | 2012 |
Variation in susceptibility to benznidazole in isolates derived from Trypanosoma cruzi parental strains VM Veloso, CM Carneiro, MJO Toledo, M Lana, E Chiari, WL Tafuri, ... Memórias do Instituto Oswaldo Cruz 96, 1005-1011, 2001 | 85 | 2001 |
Characterization and immunolocalization of an NTP diphosphohydrolase of Trypanosoma cruzi JLR Fietto, R DeMarco, IP Nascimento, IM Castro, TMU Carvalho, ... Biochemical and Biophysical Research Communications 316 (2), 454-460, 2004 | 84 | 2004 |
Impact of Trypanosoma cruzi clonal evolution on its biological properties in mice MJ de O Toledo, M De Lana, CM Carneiro, MT Bahia, ... Experimental Parasitology 100 (3), 161-172, 2002 | 84 | 2002 |
In vivo susceptibility to benznidazole of Trypanosoma cruzi strains from the western Brazilian Amazon APM Teston, WM Monteiro, D Reis, GDP Bossolani, ML Gomes, ... Tropical Medicine & International Health 18 (1), 85-95, 2013 | 78 | 2013 |
Pharmacological Characterization, Structural Studies, and In Vivo Activities of Anti-Chagas Disease Lead Compounds Derived from Tipifarnib FS Buckner, MT Bahia, PK Suryadevara, KL White, DM Shackleford, ... Antimicrobial agents and chemotherapy 56 (9), 4914-4921, 2012 | 68 | 2012 |