| Histone recognition and large-scale structural analysis of the human bromodomain family P Filippakopoulos, S Picaud, M Mangos, T Keates, JP Lambert, ... Cell 149 (1), 214-231, 2012 | 1831 | 2012 |
| A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells M Vedadi, D Barsyte-Lovejoy, F Liu, S Rival-Gervier, A Allali-Hassani, ... Nature chemical biology 7 (8), 566-574, 2011 | 580 | 2011 |
| The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis D Barsyte-Lovejoy, SK Lau, PC Boutros, F Khosravi, I Jurisica, IL Andrulis, ... Cancer research 66 (10), 5330-5337, 2006 | 569 | 2006 |
| Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth J Zhu, MA Sammons, G Donahue, Z Dou, M Vedadi, M Getlik, ... Nature 525 (7568), 206-211, 2015 | 519 | 2015 |
| An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1 KD Konze, A Ma, F Li, D Barsyte-Lovejoy, T Parton, CJ MacNevin, F Liu, ... ACS chemical biology 8 (6), 1324-1334, 2013 | 498 | 2013 |
| Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation SB Rothbart, K Krajewski, N Nady, W Tempel, S Xue, AI Badeaux, ... Nature structural & molecular biology 19 (11), 1155-1160, 2012 | 428 | 2012 |
| Protein arginine methylation: from enigmatic functions to therapeutic targeting Q Wu, M Schapira, CH Arrowsmith, D Barsyte-Lovejoy Nature reviews Drug discovery 20 (7), 509-530, 2021 | 314 | 2021 |
| Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors W Yu, EJ Chory, AK Wernimont, W Tempel, A Scopton, A Federation, ... Nature communications 3 (1), 1288, 2012 | 308 | 2012 |
| Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia F Grebien, M Vedadi, M Getlik, R Giambruno, A Grover, R Avellino, ... Nature chemical biology 11 (8), 571-578, 2015 | 302 | 2015 |
| Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP F Liu, D Barsyte-Lovejoy, F Li, Y Xiong, V Korboukh, XP Huang, ... Journal of medicinal chemistry 56 (21), 8931-8942, 2013 | 283 | 2013 |
| A potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases MS Eram, Y Shen, MM Szewczyk, H Wu, G Senisterra, F Li, KV Butler, ... ACS chemical biology 11 (3), 772-781, 2016 | 268 | 2016 |
| Therapeutic targeting of RNA splicing catalysis through inhibition of protein arginine methylation JY Fong, L Pignata, PA Goy, KC Kawabata, SCW Lee, CM Koh, D Musiani, ... Cancer cell 36 (2), 194-209. e9, 2019 | 255 | 2019 |
| Integrated (epi)-genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors J Torchia, B Golbourn, S Feng, KC Ho, P Sin-Chan, A Vasiljevic, ... Cancer cell 30 (6), 891-908, 2016 | 252 | 2016 |
| Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression DYL Mao, JD Watson, PS Yan, D Barsyte-Lovejoy, F Khosravi, ... Current Biology 13 (10), 882-886, 2003 | 250 | 2003 |
| Cancer therapeutics: targeting the dark side of Myc R Ponzielli, S Katz, D Barsyte-Lovejoy, LZ Penn European journal of cancer 41 (16), 2485-2501, 2005 | 229 | 2005 |
| Integrin α11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells CQ Zhu, SN Popova, ERS Brown, D Barsyte-Lovejoy, R Navab, W Shih, ... Proceedings of the National Academy of Sciences 104 (28), 11754-11759, 2007 | 217 | 2007 |
| The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex Y He, S Selvaraju, ML Curtin, CG Jakob, H Zhu, KM Comess, B Shaw, ... Nature chemical biology 13 (4), 389-395, 2017 | 216 | 2017 |
| Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain LI James, D Barsyte-Lovejoy, N Zhong, L Krichevsky, VK Korboukh, ... Nature chemical biology 9 (3), 184-191, 2013 | 201 | 2013 |
| (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells D Barsyte-Lovejoy, F Li, MJ Oudhoff, JH Tatlock, A Dong, H Zeng, H Wu, ... Proceedings of the National Academy of Sciences 111 (35), 12853-12858, 2014 | 194 | 2014 |
| Control of the hippo pathway by Set7-dependent methylation of Yap MJ Oudhoff, SA Freeman, AL Couzens, F Antignano, E Kuznetsova, ... Developmental cell 26 (2), 188-194, 2013 | 191 | 2013 |
