Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer O Saatci, A Kaymak, U Raza, PG Ersan, O Akbulut, CE Banister, ... Nature communications 11 (1), 2416, 2020 | 274 | 2020 |
miR-200c: a versatile watchdog in cancer progression, EMT, and drug resistance M Mutlu, U Raza, Ö Saatci, E Eyüpoğlu, E Yurdusev, Ö Şahin Journal of Molecular Medicine 94, 629-644, 2016 | 150 | 2016 |
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells A Schwab, A Siddiqui, ME Vazakidou, F Napoli, M Böttcher, B Menchicchi, ... Cancer research 78 (7), 1604-1618, 2018 | 115 | 2018 |
Endocrine resistance in breast cancer: from molecular mechanisms to therapeutic strategies O Saatci, KT Huynh-Dam, O Sahin Journal of Molecular Medicine 99 (12), 1691-1710, 2021 | 85 | 2021 |
Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer Ö Saatci, S Borgoni, Ö Akbulut, S Durmuş, U Raza, E Eyüpoğlu, C Alkan, ... Oncogene 37 (17), 2251-2269, 2018 | 78 | 2018 |
miR-564 acts as a dual inhibitor of PI3K and MAPK signaling networks and inhibits proliferation and invasion in breast cancer M Mutlu, Ö Saatci, SA Ansari, E Yurdusev, H Shehwana, Ö Konu, U Raza, ... Scientific reports 6 (1), 32541, 2016 | 74 | 2016 |
The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer U Raza, Ö Saatci, S Uhlmann, SA Ansari, E Eyüpoğlu, E Yurdusev, ... Oncotarget 7 (31), 49859, 2016 | 60 | 2016 |
Reactivation of cAMP pathway by PDE4D inhibition represents a novel druggable axis for overcoming tamoxifen resistance in ER-positive breast cancer RR Mishra, N Belder, SA Ansari, M Kayhan, H Bal, U Raza, PG Ersan, ... Clinical Cancer Research 24 (8), 1987-2001, 2018 | 56 | 2018 |
Thymidylate synthase maintains the de-differentiated state of triple negative breast cancers A Siddiqui, PN Gollavilli, A Schwab, ME Vazakidou, PG Ersan, ... Cell Death & Differentiation 26 (11), 2223-2236, 2019 | 43 | 2019 |
Systems-level Analysis Reveals Multiple Modulators of Epithelial-mesenchymal Transition and Identifies DNAJB4 and CD81 as Novel Metastasis Inducers in Breast Cancer*[S] ZCU Kagiali, E Sanal, Ö Karayel, AN Polat, Ö Saatci, PG Ersan, K Trappe, ... Molecular & Cellular Proteomics 18 (9), 1756-1771, 2019 | 38 | 2019 |
Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer R Assidicky, UM Tokat, IO Tarman, O Saatci, PG Ersan, U Raza, H Ogul, ... Breast cancer research and treatment 193 (2), 331-348, 2022 | 32 | 2022 |
Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer MA Siddiqui, PN Gollavilli, V Ramesh, B Parma, A Schwab, ... British journal of cancer 124 (1), 281-289, 2021 | 32 | 2021 |
SIK2 attenuates proliferation and survival of breast cancer cells with simultaneous perturbation of MAPK and PI3K/Akt pathways N Zohrap, Ö Saatci, B Ozes, I Coban, HM Atay, E Battaloglu, Ö Şahin, ... Oncotarget 9 (31), 21876, 2018 | 31 | 2018 |
Targeting adenosine with adenosine deaminase 2 to inhibit growth of solid tumors L Wang, LM Londono, J Cowell, O Saatci, M Aras, PG Ersan, S Serra, ... Cancer Research 81 (12), 3319-3332, 2021 | 28 | 2021 |
A highly potent TACC3 inhibitor as a novel anticancer drug candidate O Akbulut, D Lengerli, O Saatci, E Duman, UOS Seker, A Isik, A Akyol, ... Molecular cancer therapeutics 19 (6), 1243-1254, 2020 | 28 | 2020 |
CXXC5 as an unmethylated CpG dinucleotide binding protein contributes to estrogen-mediated cellular proliferation G Ayaz, N Razizadeh, P Yaşar, G Kars, DC Kahraman, Ö Saatci, Ö Şahin, ... Scientific reports 10 (1), 5971, 2020 | 21 | 2020 |
Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification O Saatci, O Akbulut, M Cetin, V Sikirzhytski, M Uner, D Lengerli, ... Cell Death & Differentiation 30 (5), 1305-1319, 2023 | 18 | 2023 |
Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis AH Janneh, MF Kassir, FC Atilgan, HG Lee, M Sheridan, N Oleinik, ... Cell reports 41 (10), 2022 | 12 | 2022 |
HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer GDS Ferretti, CE Quaas, I Bertolini, A Zuccotti, O Saatci, JA Kashatus, ... Cell Death & Differentiation, 1-16, 2024 | 10 | 2024 |
Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer O Saatci, R Alam, KT Huynh-Dam, A Isik, M Uner, N Belder, PG Ersan, ... Cell Death & Disease 15 (6), 418, 2024 | 9 | 2024 |