Követés
Thomas Farge
Thomas Farge
Assistant professor
E-mail megerősítve itt: inserm.fr
Cím
Hivatkozott rá
Hivatkozott rá
Év
Chemotherapy-resistant human acute myeloid leukemia cells are not enriched for leukemic stem cells but require oxidative metabolism
T Farge, E Saland, F De Toni, N Aroua, M Hosseini, R Perry, C Bosc, ...
Cancer discovery 7 (7), 716-735, 2017
8072017
High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells
L Poulain, P Sujobert, F Zylbersztejn, S Barreau, L Stuani, M Lambert, ...
Leukemia 31 (11), 2326-2335, 2017
1442017
Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites
C Bosc, N Broin, M Fanjul, E Saland, T Farge, C Courdy, A Batut, ...
Nature communications 11 (1), 4056, 2020
1422020
Ferritin heavy/light chain (FTH1/FTL) expression, serum ferritin levels, and their functional as well as prognostic roles in acute myeloid leukemia
S Bertoli, E Paubelle, E Bérard, E Saland, X Thomas, S Tavitian, ...
European journal of haematology 102 (2), 131-142, 2019
992019
Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia
L Stuani, M Sabatier, E Saland, G Cognet, N Poupin, C Bosc, FA Castelli, ...
Journal of Experimental Medicine 218 (5), 2021
912021
Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia
C Bosc, E Saland, A Bousard, N Gadaud, M Sabatier, G Cognet, T Farge, ...
Nature cancer 2 (11), 1204-1223, 2021
792021
Extracellular ATP and CD39 activate cAMP-mediated mitochondrial stress response to promote cytarabine resistance in acute myeloid leukemia
N Aroua, E Boet, M Ghisi, ML Nicolau-Travers, E Saland, R Gwilliam, ...
Cancer Discovery 10 (10), 1544-1565, 2020
702020
Targeting myeloperoxidase disrupts mitochondrial redox balance and overcomes cytarabine resistance in human acute myeloid leukemia
M Hosseini, HR Rezvani, N Aroua, C Bosc, T Farge, E Saland, ...
Cancer Research 79 (20), 5191-5203, 2019
622019
Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells
C Larrue, N Guiraud, PL Mouchel, M Dubois, T Farge, M Gotanègre, ...
Nature communications 12 (1), 422, 2021
512021
C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in FLT3-Mutant Leukemia
M Sabatier, R Birsen, L Lauture, S Mouche, P Angelino, J Dehairs, ...
Cancer discovery 13 (7), 1720-1747, 2023
492023
CD36 drives metastasis and relapse in acute myeloid leukemia
T Farge, J Nakhle, D Lagarde, G Cognet, N Polley, R Castellano, ...
Cancer research 83 (17), 2824-2838, 2023
342023
Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic cardiac glycoside UNBS1450 in acute myeloid leukemia
C Cerella, A Gaigneaux, A Mazumder, JY Lee, E Saland, F Radogna, ...
Leukemia 31 (3), 755-759, 2017
332017
Mesenchymal stromal cells confer chemoresistance to myeloid leukemia blasts through Side Population functionality and ABC transporter activation
L Boutin, P Arnautou, A Trignol, A Ségot, T Farge, C Desterke, S Soave, ...
Haematologica 105 (4), 987, 2019
322019
Activation of vitamin D receptor pathway enhances differentiating capacity in acute myeloid leukemia with isocitrate dehydrogenase mutations
M Sabatier, E Boet, S Zaghdoudi, N Guiraud, A Hucteau, N Polley, ...
Cancers 13 (20), 5243, 2021
132021
Thrombospondin-1 silencing improves lymphocyte infiltration in tumors and response to anti-PD-1 in triple-negative breast cancer
E Marcheteau, T Farge, M Pérès, G Labrousse, J Tenet, S Delmas, ...
Cancers 13 (16), 4059, 2021
122021
Dendrogenin A enhances anti-leukemic effect of anthracycline in acute myeloid leukemia
PL Mouchel, N Serhan, R Betous, T Farge, E Saland, P De Medina, ...
Cancers 12 (10), 2933, 2020
92020
The combination of ATRA and dasatinib for differentiation therapy in acute myeloid leukemias with IDH mutations
H Boutzen, E Saland, M Cathebras, C Larrue, T Farge, N Serhan, ...
Blood 126 (23), 2542, 2015
52015
C/EBPα confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress in FLT3-mutant leukemia
M Sabatier, R Birsen, L Lauture, J Dehairs, P Angelino, S Mouche, ...
bioRxiv, 2022.04. 15.488522, 2022
22022
Mitochondrial determinants of response and resistance to venetoclax plus cytarabine duplet therapy in acute myeloid leukemia
C Bosc, N Gadaud, A Bousard, M Sabatier, G Cognet, E Saland, T Farge, ...
BioRxiv, 2020.08. 17.253856, 2020
22020
Inflammation regulates long non-coding RNA-PTTG1-1: 1 in myeloid leukemia
S Chateauvieux, A Gaigneaux, D Gérard, M Orsini, F Morceau, ...
haematologica 105 (6), e280, 2020
22020
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Cikkek 1–20