| Tau kinetics in neurons and the human central nervous system C Sato, NR Barthélemy, KG Mawuenyega, BW Patterson, BA Gordon, ... Neuron 97 (6), 1284-1298. e7, 2018 | 602 | 2018 |
| Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates TJ Collier, NM Kanaan, JH Kordower Nature Reviews Neuroscience 12 (6), 359-366, 2011 | 552 | 2011 |
| Axonal transport defects in neurodegenerative diseases GA Morfini, M Burns, LI Binder, NM Kanaan, N LaPointe, DA Bosco, ... Journal of Neuroscience 29 (41), 12776-12786, 2009 | 545 | 2009 |
| Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration KL Paumier, KC Luk, FP Manfredsson, NM Kanaan, JW Lipton, TJ Collier, ... Neurobiology of disease 82, 185-199, 2015 | 435 | 2015 |
| Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease KR Patterson, C Remmers, Y Fu, S Brooker, NM Kanaan, L Vana, S Ward, ... Journal of Biological Chemistry 286 (26), 23063-23076, 2011 | 407 | 2011 |
| Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases NM Kanaan, GA Morfini, NE LaPointe, GF Pigino, KR Patterson, Y Song, ... Journal of Neuroscience 31 (27), 9858-9868, 2011 | 334 | 2011 |
| Liquid-liquid phase separation induces pathogenic tau conformations in vitro NM Kanaan, C Hamel, T Grabinski, B Combs Nature communications 11 (1), 2809, 2020 | 311 | 2020 |
| Extracellular tau oligomers produce an immediate impairment of LTP and memory M Fá, D Puzzo, R Piacentini, A Staniszewski, H Zhang, MA Baltrons, ... Scientific reports 6 (1), 19393, 2016 | 302 | 2016 |
| Tau oligomers and tau toxicity in neurodegenerative disease SM Ward, DS Himmelstein, JK Lancia, LI Binder Biochemical Society Transactions 40 (4), 667-671, 2012 | 290 | 2012 |
| Aging and Parkinson's disease: different sides of the same coin? TJ Collier, NM Kanaan, JH Kordower Movement Disorders 32 (7), 983-990, 2017 | 279 | 2017 |
| Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo DJ Apicco, PEA Ash, B Maziuk, C LeBlang, M Medalla, A Al Abdullatif, ... Nature neuroscience 21 (1), 72-80, 2018 | 245 | 2018 |
| Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system NM Kanaan, GF Pigino, ST Brady, O Lazarov, LI Binder, GA Morfini Experimental neurology 246, 44-53, 2013 | 240 | 2013 |
| Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration MF Duffy, TJ Collier, JR Patterson, CJ Kemp, KC Luk, MG Tansey, ... Journal of neuroinflammation 15, 1-18, 2018 | 225 | 2018 |
| Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys JH Kordower, NM Kanaan, Y Chu, R Suresh Babu, J Stansell III, ... Annals of Neurology: Official Journal of the American Neurological …, 2006 | 168 | 2006 |
| Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport KR Patterson, SM Ward, B Combs, K Voss, NM Kanaan, G Morfini, ... Biochemistry 50 (47), 10300-10310, 2011 | 134 | 2011 |
| Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline DJ Koss, G Jones, A Cranston, H Gardner, NM Kanaan, B Platt Acta neuropathologica 132, 875-895, 2016 | 133 | 2016 |
| A method for combining RNAscope in situ hybridization with immunohistochemistry in thick free-floating brain sections and primary neuronal cultures TM Grabinski, A Kneynsberg, FP Manfredsson, NM Kanaan PloS one 10 (3), e0120120, 2015 | 133 | 2015 |
| Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport NM Kanaan, G Morfini, G Pigino, NE LaPointe, A Andreadis, Y Song, ... Neurobiology of aging 33 (4), 826. e15-826. e30, 2012 | 132 | 2012 |
| Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease L Vana, NM Kanaan, IC Ugwu, J Wuu, EJ Mufson, LI Binder The American journal of pathology 179 (5), 2533-2550, 2011 | 131 | 2011 |
| Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy L Jiang, W Lin, C Zhang, PEA Ash, M Verma, J Kwan, E van Vliet, Z Yang, ... Molecular cell 81 (20), 4209-4227. e12, 2021 | 128 | 2021 |
