Emerging roles of E2Fs in cancer: an exit from cell cycle control HZ Chen, SY Tsai, G Leone Nature reviews cancer 9 (11), 785-797, 2009 | 1127 | 2009 |
TOR and ageing: a complex pathway for a complex process MA McCormick, S Tsai, BK Kennedy Philosophical Transactions of the Royal Society B: Biological Sciences 366 …, 2011 | 136 | 2011 |
Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity S Tsai, JM Sitzmann, SG Dastidar, AA Rodriguez, SL Vu, CE McDonald, ... The Journal of clinical investigation 125 (8), 2952-2964, 2015 | 127 | 2015 |
Mouse development with a single E2F activator SY Tsai, R Opavsky, N Sharma, L Wu, S Naidu, E Nolan, E Feria-Arias, ... Nature 454 (7208), 1137-1141, 2008 | 127 | 2008 |
Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma LN Kent, S Bae, SY Tsai, X Tang, A Srivastava, C Koivisto, CK Martin, ... The Journal of clinical investigation 127 (3), 830-842, 2017 | 114 | 2017 |
E2f3a and E2f3b Contribute to the Control of Cell Proliferation and Mouse Development JL Chong, SY Tsai, N Sharma, R Opavsky, R Price, L Wu, SA Fernandez, ... Molecular and cellular biology 29 (2), 414-424, 2009 | 104 | 2009 |
A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery HWS Tan, G Lu, H Dong, YL Cho, A Natalia, L Wang, C Chan, D Kappei, ... Nature communications 13 (1), 3720, 2022 | 80 | 2022 |
Increased 4E-BP1 expression protects against diet-induced obesity and insulin resistance in male mice SY Tsai, AA Rodriguez, SG Dastidar, E Del Greco, KL Carr, JM Sitzmann, ... Cell reports 16 (7), 1903-1914, 2016 | 72 | 2016 |
Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis R Opavsky, SY Tsai, M Guimond, A Arora, J Opavska, B Becknell, ... Proceedings of the National Academy of Sciences 104 (39), 15400-15405, 2007 | 69 | 2007 |
Tissue-specific targeting of cell fate regulatory genes by E2f factors LM Julian, Y Liu, CA Pakenham, D Dugal-Tessier, V Ruzhynsky, S Bae, ... Cell Death & Differentiation 23 (4), 565-575, 2016 | 38 | 2016 |
Sarcopenia: tilting the balance of protein homeostasis KT Tan, STJ Ang, SY Tsai Proteomics 20 (5-6), 1800411, 2020 | 37 | 2020 |
Interaction of Saccharomyces Cdc13p with Pol1p, Imp4p, Sir4p and Zds2p is involved in telomere replication, telomere maintenance and cell growth control CL Hsu, YS Chen, SY Tsai, PJ Tu, MJ Wang, JJ Lin Nucleic acids research 32 (2), 511-521, 2004 | 35 | 2004 |
Mitochondrial properties in skeletal muscle fiber H Dong, SY Tsai Cells 12 (17), 2183, 2023 | 33 | 2023 |
Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in mice STJ Ang, EM Crombie, H Dong, KT Tan, A Hernando, D Yu, S Adamson, ... Nature Communications 13 (1), 7792, 2022 | 16 | 2022 |
Activation of eIF4E‐binding‐protein‐1 rescues mTORC1‐induced sarcopenia by expanding lysosomal degradation capacity EM Crombie, S Kim, S Adamson, H Dong, TC Lu, Y Wu, Y Wu, Y Levy, ... Journal of cachexia, sarcopenia and muscle 14 (1), 198-213, 2023 | 13 | 2023 |
Paraspinal myopathy-induced intervertebral disc degeneration and thoracolumbar kyphosis in TSC1mKO mice model—A preliminary study HWD Hey, WMR Lam, CX Chan, WH Zhuo, EM Crombie, TC Tan, ... The Spine Journal 22 (3), 483-494, 2022 | 11 | 2022 |
Lost in translation: challenges of current pharmacotherapy for sarcopenia SY Tsai Trends in Molecular Medicine, 2024 | 7 | 2024 |
Limiting cap-dependent translation increases 20S proteasomal degradation and protects the proteomic integrity in autophagy-deficient skeletal muscle H Dong, Y Lyu, CY Huang, SY Tsai Autophagy, 2025 | | 2025 |
Role of chronic activation of muscle mTORC1-induced sarcopenia and its effects on muscle regeneration and myogenic differentiation of muscle stem cells EM Crombie, TS Yin, P Hutchinson, Z Wenhai, J Ochala 研究結果報告書集: 交通事故・各種災害の防止等分野・高齢者福祉分野 24, 133-140, 2018 | | 2018 |
筋肉 mTORC1 によって誘発されたサルコペニアの長期活性化の役割と筋再生と筋肉幹細胞の筋原生分化へのその影響 EM Crombie, SY Tsai, P Hutchinson, W Zhou, J Ochala 研究結果報告書集: 交通安全等・高齢者福祉 24, 133-140, 2018 | | 2018 |