Stage-dependent alterations of the serum cytokine pattern in colorectal carcinoma T Kantola, K Klintrup, JP Väyrynen, J Vornanen, R Bloigu, T Karhu, ... British journal of cancer 107 (10), 1729-1736, 2012 | 281 | 2012 |
Systemic inflammation in colorectal cancer: Underlying factors, effects, and prognostic significance AE Tuomisto, MJ Mäkinen, JP Väyrynen World journal of gastroenterology 25 (31), 4383, 2019 | 258 | 2019 |
IL-17/Th17 pathway is activated in acne lesions HL Kelhälä, R Palatsi, N Fyhrquist, S Lehtimäki, JP Väyrynen, ... PloS one 9 (8), e105238, 2014 | 210 | 2014 |
Detailed analysis of inflammatory cell infiltration in colorectal cancer JP Väyrynen, A Tuomisto, K Klintrup, J Mäkelä, TJ Karttunen, MJ Mäkinen British journal of cancer 109 (7), 1839-1847, 2013 | 172 | 2013 |
Preoperative anemia in colorectal cancer: relationships with tumor characteristics, systemic inflammation, and survival JP Väyrynen, A Tuomisto, SA Väyrynen, K Klintrup, T Karhu, J Mäkelä, ... Scientific reports 8 (1), 1126, 2018 | 149 | 2018 |
The prognostic role of macrophage polarization in the colorectal cancer microenvironment JP Väyrynen, K Haruki, MC Lau, SA Väyrynen, R Zhong, A Dias Costa, ... Cancer immunology research 9 (1), 8-19, 2021 | 145 | 2021 |
Characteristics and significance of colorectal cancer associated lymphoid reaction JP Väyrynen, SA Sajanti, K Klintrup, J Mäkelä, KH Herzig, TJ Karttunen, ... International journal of cancer 134 (9), 2126-2135, 2014 | 137 | 2014 |
Composition, spatial characteristics, and prognostic significance of myeloid cell infiltration in pancreatic cancer SA Väyrynen, J Zhang, C Yuan, JP Väyrynen, A Dias Costa, H Williams, ... Clinical Cancer Research 27 (4), 1069-1081, 2021 | 116 | 2021 |
An improved image analysis method for cell counting lends credibility to the prognostic significance of T cells in colorectal cancer JP Väyrynen, JO Vornanen, S Sajanti, JP Böhm, A Tuomisto, MJ Mäkinen Virchows Archiv 460, 455-465, 2012 | 111 | 2012 |
Decreased serum apolipoprotein A1 levels are associated with poor survival and systemic inflammatory response in colorectal cancer P Sirniö, JP Väyrynen, K Klintrup, J Mäkelä, MJ Mäkinen, TJ Karttunen, ... Scientific reports 7 (1), 5374, 2017 | 101 | 2017 |
Prognostic and predictive role of tumour-associated macrophages in HER2 positive breast cancer TJ Honkanen, A Tikkanen, P Karihtala, M Mäkinen, JP Väyrynen, ... Scientific reports 9 (1), 10961, 2019 | 97 | 2019 |
Serum MMP‐8 levels increase in colorectal cancer and correlate with disease course and inflammatory properties of primary tumors JP Väyrynen, J Vornanen, T Tervahartiala, T Sorsa, R Bloigu, T Salo, ... International journal of cancer 131 (4), E463-E474, 2012 | 90 | 2012 |
Association of machine learning–based assessment of tumor-infiltrating lymphocytes on standard histologic images with outcomes of immunotherapy in patients with NSCLC M Rakaee, E Adib, B Ricciuti, LM Sholl, W Shi, JV Alessi, A Cortellini, ... JAMA oncology 9 (1), 51-60, 2023 | 87 | 2023 |
Immunoscore in mismatch repair‐proficient and‐deficient colon cancer EV Wirta, T Seppälä, M Friman, J Väyrynen, M Ahtiainen, H Kautiainen, ... The Journal of Pathology: Clinical Research 3 (3), 203-213, 2017 | 85 | 2017 |
Clinical impact and network of determinants of tumour necrosis in colorectal cancer SA Väyrynen, JP Väyrynen, K Klintrup, J Mäkelä, TJ Karttunen, ... British journal of cancer 114 (12), 1334-1342, 2016 | 84 | 2016 |
Histopathology images predict multi-omics aberrations and prognoses in colorectal cancer patients PC Tsai, TH Lee, KC Kuo, FY Su, TLM Lee, E Marostica, T Ugai, M Zhao, ... Nature communications 14 (1), 1-13, 2023 | 77 | 2023 |
Alterations in serum amino-acid profile in the progression of colorectal cancer: associations with systemic inflammation, tumour stage and patient survival P Sirniö, JP Väyrynen, K Klintrup, J Mäkelä, T Karhu, KH Herzig, ... British journal of cancer 120 (2), 238-246, 2019 | 76 | 2019 |
High-serum MMP-8 levels are associated with decreased survival and systemic inflammation in colorectal cancer P Sirniö, A Tuomisto, T Tervahartiala, T Sorsa, K Klintrup, T Karhu, ... British journal of cancer 119 (2), 213-219, 2018 | 75 | 2018 |
Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment J Borowsky, K Haruki, MC Lau, A Dias Costa, JP Väyrynen, T Ugai, ... Clinical Cancer Research 27 (10), 2816-2826, 2021 | 73 | 2021 |
Western-style diet, pks island-carrying Escherichia coli, and colorectal cancer: analyses from two large prospective cohort studies K Arima, R Zhong, T Ugai, M Zhao, K Haruki, N Akimoto, MC Lau, ... Gastroenterology 163 (4), 862-874, 2022 | 68 | 2022 |