In vitro and in vivo pharmacological profile of AS057278, a selective d-amino acid oxidase inhibitor with potential anti-psychotic properties T Adage, AC Trillat, A Quattropani, D Perrin, L Cavarec, J Shaw, ... European Neuropsychopharmacology 18 (3), 200-214, 2008 | 147 | 2008 |
A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice EA Liehn, AM Piccinini, RR Koenen, O Soehnlein, T Adage, R Fatu, ... Journal of the American College of Cardiology 56 (22), 1847-1857, 2010 | 136 | 2010 |
Hypothalamic, metabolic, and behavioral responses to pharmacological inhibition of CNS melanocortin signaling in rats T Adage, AJW Scheurink, SF de Boer, K de Vries, JP Konsman, F Kuipers, ... Journal of Neuroscience 21 (10), 3639-3645, 2001 | 136 | 2001 |
Cytokines and chemokines in SARS-CoV-2 infections—therapeutic strategies targeting cytokine storm A Pum, M Ennemoser, T Adage, AJ Kungl Biomolecules 11 (1), 91, 2021 | 92 | 2021 |
Glycosaminoglycans are important mediators of neutrophilic inflammation in vivo M Gschwandtner, E Strutzmann, MM Teixeira, HJ Anders, ... Cytokine 91, 65-73, 2017 | 45 | 2017 |
Structure‐based design of decoy chemokines as a way to explore the pharmacological potential of glycosaminoglycans T Adage, AM Piccinini, A Falsone, M Trinker, J Robinson, B Gesslbauer, ... British journal of pharmacology 167 (6), 1195-1205, 2012 | 45 | 2012 |
Targeting of CCL2-CCR2-glycosaminoglycan axis using a CCL2 decoy protein attenuates metastasis through inhibition of tumor cell seeding M Roblek, E Strutzmann, C Zankl, T Adage, M Heikenwalder, A Atlic, ... Neoplasia 18 (1), 49-59, 2016 | 44 | 2016 |
Designing CXCL8-based decoy proteins with strong anti-inflammatory activity in vivo A Falsone, V Wabitsch, E Geretti, H Potzinger, T Gerlza, J Robinson, ... Bioscience reports 33 (5), e00068, 2013 | 42 | 2013 |
A novel role for receptor like protein tyrosine phosphatase zeta in modulation of sensorimotor responses to noxious stimuli: evidences from knockout mice studies D Lafont, T Adage, B Gréco, P Zaratin Behavioural brain research 201 (1), 29-40, 2009 | 35 | 2009 |
Hypothalamic histamine release in normal and stressed rats is affected by sex and aging C Ferretti, M Blengio, P Ghi, T Adage, P Portaleone, SR Gamalero Pharmacology Biochemistry and Behavior 59 (1), 255-260, 1998 | 29 | 1998 |
PA401, a novel CXCL8-based biologic therapeutic with increased glycosaminoglycan binding, reduces bronchoalveolar lavage neutrophils and systemic inflammatory markers in a … T Adage, F Del Bene, F Fiorentini, RP Doornbos, C Zankl, MR Bartley, ... Cytokine 76 (2), 433-441, 2015 | 21 | 2015 |
The effect of the decoy molecule PA401 on CXCL8 levels in bronchoalveolar lavage fluid of patients with cystic fibrosis OJ McElvaney, N O’Reilly, M White, N Lacey, K Pohl, T Gerlza, DA Bergin, ... Molecular immunology 63 (2), 550-558, 2015 | 21 | 2015 |
Feeding and temperature responses to intravenous leptin infusion are differential predictors of obesity in rats MP Ruffin, T Adage, F Kuipers, JH Strubbe, AJW Scheurink, G van Dijk American Journal of Physiology-Regulatory, Integrative and Comparative …, 2004 | 21 | 2004 |
Targeting glycosaminoglycans in the lung by an engineered CXCL8 as a novel therapeutic approach to lung inflammation T Adage, V Konya, C Weber, E Strutzmann, T Fuchs, C Zankl, T Gerlza, ... European Journal of Pharmacology 748, 83-92, 2015 | 19 | 2015 |
Interfering with the CCL2–glycosaminoglycan axis as a potential approach to modulate neuroinflammation M Gschwandtner, AM Piccinini, T Gerlza, T Adage, AJ Kungl Neuroscience Letters 626, 164-173, 2016 | 17 | 2016 |
Designing a mutant CCL2-HSA chimera with high glycosaminoglycan-binding affinity and selectivity T Gerlza, S Winkler, A Atlic, C Zankl, V Konya, N Kitic, E Strutzmann, ... Protein Engineering, Design & Selection 28 (8), 231-240, 2015 | 15 | 2015 |
N-Acetyltransferase mechanism for α-melanocyte stimulating hormone regulation in rat ageing L Cangemi, T Adage, A Morabito, P Portaleone Neuroscience letters 201 (1), 65-68, 1995 | 14 | 1995 |
New targets for glycosaminoglycans and glycosaminoglycans as novel targets B Gesslbauer, M Theuer, D Schweiger, T Adage, AJ Kungl Expert Review of Proteomics 10 (1), 77-95, 2013 | 13 | 2013 |
In vitro and in vivo testing of a novel local nicardipine delivery system to the brain: a preclinical study VP • S.H. Bayerl, A. Ghori, M. Nieminen-Kelha, T. Adage, J. Breitenbach, P ... Journal of Neurosurgery 132 (2), 465-472, 2019 | 11 | 2019 |
Glycosaminoglycan silencing by engineered CXCL12 variants M Gschwandtner, MU Trinker, B Hecher, T Adage, S Ali, AJ Kungl FEBS letters 589 (19), 2819-2824, 2015 | 11 | 2015 |