Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1, 2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug MC Vega, M Rolón, A Montero-Torres, C Fonseca-Berzal, JA Escario, ... European journal of medicinal chemistry 58, 214-227, 2012 | 63 | 2012 |
Development of novel benznidazole formulations: physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease R Palmeiro-Roldán, C Fonseca-Berzal, A Gómez-Barrio, VJ Arán, ... International journal of pharmaceutics 472 (1-2), 110-117, 2014 | 49 | 2014 |
Selective activity of 2, 4-diaryl-1, 2, 3, 4-tetrahydroquinolines on Trypanosoma cruzi epimastigotes and amastigotes expressing β-galactosidase C Fonseca-Berzal, DRM Arenas, ARR Bohórquez, JA Escario, ... Bioorganic & medicinal chemistry letters 23 (17), 4851-4856, 2013 | 49 | 2013 |
Novel solid dispersions of benznidazole: preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system C Fonseca-Berzal, R Palmeiro-Roldán, JA Escario, S Torrado, VJ Arán, ... Experimental parasitology 149, 84-91, 2015 | 40 | 2015 |
Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles C Fonseca-Berzal, A Ibanez-Escribano, F Reviriego, J Cumella, ... European journal of medicinal chemistry 115, 295-310, 2016 | 37 | 2016 |
Experimental models in Chagas disease: A review of the methodologies applied for screening compounds against Trypanosoma cruzi C Fonseca-Berzal, VJ Arán, JA Escario, A Gómez-Barrio Parasitology research 117 (11), 3367-3380, 2018 | 32 | 2018 |
In vitro phenotypic screening of 7-chloro-4-amino (oxy) quinoline derivatives as putative anti-Trypanosoma cruzi agents C Fonseca-Berzal, FAR Ruiz, JA Escario, VV Kouznetsov, ... Bioorganic & medicinal chemistry letters 24 (4), 1209-1213, 2014 | 31 | 2014 |
Imidazole derivatives as promising agents for the treatment of Chagas disease JS de Araújo, A Garcia-Rubia, V Sebastian-Perez, TD Kalejaiye, ... Antimicrobial agents and chemotherapy 63 (4), e02156-18, 2019 | 29 | 2019 |
Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2‐Benzyl‐5‐nitroindazole‐Derived Amines C Fonseca‐Berzal, A Ibáñez‐Escribano, N Vela, J Cumella, ... ChemMedChem 13 (12), 1246-1259, 2018 | 23 | 2018 |
Further insights into biological evaluation of new anti-Trypanosoma cruzi 5-nitroindazoles C Fonseca-Berzal, JA Escario, VJ Arán, A Gómez-Barrio Parasitology research 113 (3), 1049-1056, 2014 | 21 | 2014 |
Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis A Ibáñez-Escribano, C Fonseca-Berzal, M Martínez-Montiel, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 781-791, 2022 | 17 | 2022 |
New imidazole-based compounds active against Trypanosoma cruzi O Stephen Adeyemi, M Teresa Molina, A Omokehinde Eseola, ... Combinatorial chemistry & high throughput screening 20 (1), 20-24, 2017 | 17 | 2017 |
Efficacy of novel pyrazolone phosphodiesterase inhibitors in experimental mouse models of Trypanosoma cruzi JS de Araújo, C França da Silva, DGJ Batista, A Nefertiti, LFA Fiuza, ... Antimicrobial agents and chemotherapy 64 (9), e00414-20, 2020 | 13 | 2020 |
Novel Imidazo [4, 5-c][1, 2, 6] thiadiazine 2, 2-dioxides as antiproliferative Trypanosoma cruzi drugs: Computational screening from neural network, synthesis and in vivo … A Guerra, P Gonzalez-Naranjo, NE Campillo, J Varela, ML Lavaggi, ... European journal of medicinal chemistry 136, 223-234, 2017 | 13 | 2017 |
Exploring the potential activity spectrum of two 5-nitroindazolinone prototypes on different Trypanosoma cruzi strains C Fonseca-Berzal, PB DA SILVA, CF DA SILVA, M Vasconcelos, ... Parasitology Open 1, 2015 | 13 | 2015 |
Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes C Fonseca-Berzal, CF DA SILVA, RFS Menna-Barreto, MM Batista, ... Parasitology 143 (11), 1469-1478, 2016 | 12 | 2016 |
Synthesis and Biophysical and Biological Studies of N-Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites JJ Nué-Martinez, D Cisneros, MV Moreno-Blázquez, C Fonseca-Berzal, ... Journal of Medicinal Chemistry, 2023 | 9 | 2023 |
Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles A Ibáñez-Escribano, F Reviriego, N Vela, C Fonseca-Berzal, ... Bioorganic & Medicinal Chemistry Letters 37, 127843, 2021 | 8 | 2021 |
Trypanocidal activity of long chain diamines and aminoalcohols AL Legarda-Ceballos, E Del Olmo, J López-Abán, R Escarcena, ... Molecules 20 (6), 11554-11568, 2015 | 6 | 2015 |
Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Trypanosoma cruzi Y strain (DTU TcII): in vitro and in vivo studies C Fonseca-Berzal, CF da Silva, DGJ Batista, GM de Oliveira, J Cumella, ... Parasitology 147 (11), 1216-1228, 2020 | 5 | 2020 |