Követés
Clemens Zwergel
Clemens Zwergel
Assistant Professor, Department of Drug Chemistry and Technologies
E-mail megerősítve itt: uniroma1.it - Kezdőlap
Cím
Hivatkozott rá
Hivatkozott rá
Év
The emerging role of epigenetics in human autoimmune disorders
R Mazzone, C Zwergel, M Artico, S Taurone, M Ralli, A Greco, A Mai
Clinical epigenetics 11, 1-15, 2019
2832019
Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy
R Mazzone, C Zwergel, A Mai, S Valente
Clinical epigenetics 9 (1), 59, 2017
1482017
Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells
S Valente, Y Liu, M Schnekenburger, C Zwergel, S Cosconati, C Gros, ...
Journal of medicinal chemistry 57 (3), 701-713, 2014
1332014
The innovative potential of statins in cancer: new targets for new therapies
E Di Bello, C Zwergel, A Mai, S Valente
Frontiers in chemistry 8, 516, 2020
1072020
Six years (2012–2018) of researches on catalytic ezh2 inhibitors: the boom of the 2‐pyridone compounds
R Fioravanti, G Stazi, C Zwergel, S Valente, A Mai
The Chemical Record 18 (12), 1818-1832, 2018
1072018
Aurones: interesting natural and synthetic compounds with emerging biological potential
C Zwergel, F Gaascht, S Valente, M Diederich, D Bagrel, G Kirsch
Natural product communications 7 (3), 1934578X1200700322, 2012
1012012
1, 4-Dihydropyridines active on the SIRT1/AMPK pathway ameliorate skin repair and mitochondrial function and exhibit inhibition of proliferation in cancer cells
S Valente, P Mellini, F Spallotta, V Carafa, A Nebbioso, L Polletta, ...
Journal of Medicinal Chemistry 59 (4), 1471-1491, 2016
812016
Emerging approaches for histone deacetylase inhibitor drug discovery
C Zwergel, S Valente, C Jacob, A Mai
Expert opinion on drug discovery 10 (6), 599-613, 2015
802015
Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells
G Di Pompo, M Salerno, D Rotili, S Valente, C Zwergel, S Avnet, ...
Journal of medicinal chemistry 58 (9), 4073-4079, 2015
782015
The innovative potential of selenium-containing agents for fighting cancer and viral infections
W Ali, R Benedetti, J Handzlik, C Zwergel, C Battistelli
Drug Discovery Today 26 (1), 256-263, 2021
752021
m6A RNA methylation and beyond–The epigenetic machinery and potential treatment options
S Garbo, C Zwergel, C Battistelli
Drug discovery today 26 (11), 2559-2574, 2021
722021
GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug design
C Castiello, P Junghanns, A Mergel, C Jacob, C Ducho, S Valente, ...
Green Chemistry 25 (6), 2109-2169, 2023
702023
DNA methyltransferases inhibitors from natural sources
C Zwergel, S Valente, A Mai
Current topics in medicinal chemistry 16 (7), 680-696, 2016
692016
Histone deacetylase inhibitors: updated studies in various epigenetic-related diseases
C Zwergel, G Stazi, S Valente, A Mai
J Clin Epigenetics 2 (1), 7, 2016
622016
Design of first-in-class dual EZH2/HDAC inhibitor: biochemical activity and biological evaluation in cancer cells
A Romanelli, G Stazi, R Fioravanti, C Zwergel, E Di Bello, S Pomella, ...
ACS medicinal chemistry letters 11 (5), 977-983, 2020
602020
EZH2 inhibitors: a patent review (2014-2016)
G Stazi, C Zwergel, A Mai, S Valente
Expert opinion on therapeutic patents 27 (7), 797-813, 2017
602017
LSD1 inhibitors: a patent review (2010-2015)
G Stazi, C Zwergel, S Valente, A Mai
Expert Opinion on Therapeutic Patents 26 (5), 565-580, 2016
592016
Novel benzofuran–chromone and–coumarin derivatives: synthesis and biological activity in K562 human leukemia cells
C Zwergel, S Valente, A Salvato, Z Xu, O Talhi, A Mai, A Silva, L Altucci, ...
MedChemComm 4 (12), 1571-1579, 2013
562013
Sirtuin modulators: where are we now? A review of patents from 2015 to 2019
N Mautone, C Zwergel, A Mai, D Rotili
Expert Opinion on Therapeutic Patents 30 (6), 389-407, 2020
552020
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells
E Miele, S Valente, V Alfano, M Silvano, P Mellini, D Borovika, B Marrocco, ...
Oncotarget 8 (40), 68557, 2017
552017
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