Követés
Philip Van Damme
Philip Van Damme
Professor of Neuroscience, University of Leuven
E-mail megerősítve itt: uzleuven.be
Cím
Hivatkozott rá
Hivatkozott rá
Év
EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)–revised report of an EFNS task force
EFNS Task Force on Diagnosis and Management of Amyotrophic Lateral Sclerosis:
European journal of neurology 19 (3), 360-375, 2012
11532012
Amyotrophic lateral sclerosis: a clinical review
P Masrori, P Van Damme
European journal of neurology 27 (10), 1918-1929, 2020
10102020
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
International Multiple Sclerosis Genetics Consortium*†, ANZgene, ...
Science 365 (6460), eaav7188, 2019
8622019
Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind …
JF Howard, K Utsugisawa, M Benatar, H Murai, RJ Barohn, I Illa, S Jacob, ...
The Lancet Neurology 16 (12), 976-986, 2017
6902017
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1267-1288, 2018
6662018
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ...
Nature genetics 48 (9), 1043-1048, 2016
6332016
The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis
L Van Den Bosch, P Van Damme, E Bogaert, W Robberecht
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (11-12 …, 2006
6262006
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
E Storkebaum, D Lambrechts, M Dewerchin, MP Moreno-Murciano, ...
Nature neuroscience 8 (1), 85-92, 2005
6222005
Gain of toxicity from ALS/FTD-linked repeat expansions in C9ORF72 is alleviated by antisense oligonucleotides targeting GGGGCC-containing RNAs
J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ...
Neuron 90 (3), 535-550, 2016
6192016
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
TM Miller, ME Cudkowicz, A Genge, PJ Shaw, G Sobue, RC Bucelli, ...
New England Journal of Medicine 387 (12), 1099-1110, 2022
5842022
HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease
C d'Ydewalle, J Krishnan, DM Chiheb, P Van Damme, J Irobi, ...
Nature medicine 17 (8), 968-974, 2011
5842011
Phase separation of C9orf72 dipeptide repeats perturbs stress granule dynamics
S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ...
Molecular cell 65 (6), 1044-1055. e5, 2017
5532017
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ...
New England Journal of Medicine 383 (2), 109-119, 2020
5382020
Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model
HJ Westeneng, TPA Debray, AE Visser, RPA van Eijk, JPK Rooney, ...
The Lancet Neurology 17 (5), 423-433, 2018
5072018
Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival
P Van Damme, A Van Hoecke, D Lambrechts, P Vanacker, E Bogaert, ...
The Journal of cell biology 181 (1), 37-41, 2008
4862008
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
W Van Rheenen, RAA Van Der Spek, MK Bakker, JJFA Van Vugt, PJ Hop, ...
Nature genetics 53 (12), 1636-1648, 2021
3982021
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients
W Guo, M Naujock, L Fumagalli, T Vandoorne, P Baatsen, R Boon, ...
Nature communications 8 (1), 861, 2017
3852017
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
A Van Hoecke, L Schoonaert, R Lemmens, M Timmers, KA Staats, ...
Nature medicine 18 (9), 1418-1422, 2012
3642012
Regional variation of Guillain-Barré syndrome
AY Doets, C Verboon, B Van Den Berg, T Harbo, DR Cornblath, ...
Brain 141 (10), 2866-2877, 2018
3522018
The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter
I Gijselinck, S Van Mossevelde, J van der Zee, A Sieben, S Engelborghs, ...
Molecular psychiatry 21 (8), 1112-1124, 2016
3132016
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