Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice SA Villeda, KE Plambeck, J Middeldorp, JM Castellano, KI Mosher, J Luo, ... Nature medicine 20 (6), 659-663, 2014 | 1200 | 2014 |
TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge AA Nugent, K Lin, B Van Lengerich, S Lianoglou, L Przybyla, SS Davis, ... Neuron 105 (5), 837-854. e9, 2020 | 511 | 2020 |
β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis LK Smith, Y He, JS Park, G Bieri, CE Snethlage, K Lin, G Gontier, R Wabl, ... Nature medicine 21 (8), 932-937, 2015 | 505 | 2015 |
Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia BJ Andreone, L Przybyla, C Llapashtica, A Rana, SS Davis, ... Nature Neuroscience 23 (8), 927-938, 2020 | 192 | 2020 |
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia D Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, ... Molecular Neurodegeneration 17 (1), 41, 2022 | 71 | 2022 |
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist A Litvinchuk, JH Suh, JL Guo, K Lin, SS Davis, N Bien-Ly, E Tycksen, ... Neuron 112 (3), 384-403. e8, 2024 | 50 | 2024 |
The aged hematopoietic system promotes hippocampal‐dependent cognitive decline LK Smith, E Verovskaya, G Bieri, AM Horowitz, ... Aging cell 19 (8), e13192, 2020 | 25 | 2020 |
MHC class I H2-Kb negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling K Lin, G Bieri, G Gontier, S Müller, LK Smith, CE Snethlage, CW White III, ... PLoS biology 19 (6), e3001311, 2021 | 24 | 2021 |
Fibrillar Aβ causes profound microglial metabolic perturbations in a novel APP knock-in mouse model D Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, ... bioRxiv, 2021.01. 19.426731, 2021 | 9 | 2021 |
Fat Chance for Neural Stem Cells in Alzheimer’s Disease G Gontier, K Lin, SA Villeda Cell stem cell 17 (4), 373-374, 2015 | 5 | 2015 |
Chromatin regulator Kdm6b is required for the establishment and maintenance of neural stem cells in mouse hippocampus E Gil, SJ Hong, D Wu, DH Park, RN Delgado, M Malatesta, SH Ahanger, ... bioRxiv, 2024.02. 20.581302, 2024 | | 2024 |