Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy B Lo, K Zhang, W Lu, L Zheng, Q Zhang, C Kanellopoulou, Y Zhang, Z Liu, ... Science 349 (6246), 436-440, 2015 | 725 | 2015 |
The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease Z Liu, J Lee, S Krummey, W Lu, H Cai, MJ Lenardo Nature immunology 12 (11), 1063-1070, 2011 | 412 | 2011 |
Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release W Lu, BJ Zheng, K Xu, W Schwarz, L Du, CKL Wong, J Chen, S Duan, ... Proceedings of the National Academy of Sciences 103 (33), 12540-12545, 2006 | 373 | 2006 |
PEDV ORF3 encodes an ion channel protein and regulates virus production K Wang, W Lu, J Chen, S Xie, H Shi, H Hsu, W Yu, K Xu, C Bian, ... FEBS letters 586 (4), 384-391, 2012 | 218 | 2012 |
Congenital B cell lymphocytosis explained by novel germline CARD11 mutations AL Snow, W Xiao, JR Stinson, W Lu, B Chaigne-Delalande, L Zheng, ... Journal of Experimental Medicine 209 (12), 2247-2261, 2012 | 207 | 2012 |
Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson’s-like movement disorder W Lu, SS Karuppagounder, DA Springer, MD Allen, L Zheng, B Chao, ... Nature communications 5 (1), 4930, 2014 | 159 | 2014 |
Mitochondrial protein PGAM5 regulates mitophagic protection against cell necroptosis W Lu, J Sun, JS Yoon, Y Zhang, L Zheng, E Murphy, MP Mattson, ... PloS one 11 (1), e0147792, 2016 | 157 | 2016 |
Identification of an epitope of SARS-coronavirus nucleocapsid protein Y Lin, X Shen, RF Yang, YX Li, YY Ji, YY He, MD Shi, W Lu, TL Shi, ... Cell research 13 (3), 141-145, 2003 | 131 | 2003 |
Severe acute respiratory syndrome coronavirus accessory protein 9b is a virion-associated protein K Xu, BJ Zheng, R Zeng, W Lu, YP Lin, L Xue, L Li, LL Yang, C Xu, J Dai, ... Virology 388 (2), 279-285, 2009 | 72 | 2009 |
Dual proteolytic pathways govern glycolysis and immune competence W Lu, Y Zhang, DO McDonald, H Jing, B Carroll, N Robertson, Q Zhang, ... Cell 159 (7), 1578-1590, 2014 | 69 | 2014 |
DIDS blocks a chloride-dependent current that is mediated by the 2B protein of enterovirus 71 S Xie, K Wang, W Yu, W Lu, K Xu, J Wang, B Ye, W Schwarz, Q Jin, B Sun Cell research 21 (8), 1271-1275, 2011 | 55 | 2011 |
Broad humoral and cellular immunity elicited by a bivalent DNA vaccine encoding HA and NP genes from an H5N1 virus K Xu, ZY Ling, L Sun, Y Xu, C Bian, Y He, W Lu, Z Chen, B Sun Viral immunology 24 (1), 45-56, 2011 | 51 | 2011 |
Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential W Lu, XD Wu, MD Shi, RF Yang, YY He, C Bian, TL Shi, S Yang, XL Zhu, ... FEBS letters 579 (10), 2130-2136, 2005 | 30 | 2005 |
SARS accessory proteins ORF3a and 9b and their functional analysis W Lu, K Xu, B Sun Molecular biology of the SARS-coronavirus, 167-175, 2010 | 25 | 2010 |
ZMYND8 mediated liquid condensates spatiotemporally decommission the latent super-enhancers during macrophage polarization P Jia, X Li, X Wang, L Yao, Y Xu, Y Hu, W Xu, Z He, Q Zhao, Y Deng, ... Nature Communications 12 (1), 6535, 2021 | 23 | 2021 |
Conserved amino acids W423 and N424 in receptor-binding domain of SARS-CoV are potential targets for therapeutic monoclonal antibody C Bian, X Zhang, X Cai, L Zhang, Z Chen, Y Zha, Y Xu, K Xu, W Lu, L Yan, ... Virology 383 (1), 39-46, 2009 | 22 | 2009 |
Pathogenic CARD11 mutations affect B cell development and differentiation through a noncanonical pathway Z Wei, Y Zhang, J Chen, Y Hu, P Jia, X Wang, Q Zhao, Y Deng, N Li, ... Science immunology 4 (41), eaaw5618, 2019 | 21 | 2019 |
Leucine-rich repeat kinase 2 (LRRK2) regulates inflammatory bowel disease through the Nuclear Factor of Activated T cells (NFAT) Z Liu, J Lee, S Krummey, W Lu, H Cai, MJ Lenardo Nature immunology 12 (11), 1063, 2011 | 10 | 2011 |
Targeted knockdown of PGAM5 in synovial macrophages efficiently alleviates osteoarthritis Y Liu, R Hao, J Lv, J Yuan, X Wang, C Xu, D Ma, Z Duan, B Zhang, L Dai, ... Bone research 12 (1), 15, 2024 | 8 | 2024 |
CARD11 regulates the thymic Treg development in an NF-κB-independent manner Y Hu, L Han, W Xu, T Li, Q Zhao, W Lu, J Sun, Y Wang Frontiers in Immunology 15, 1364957, 2024 | 2 | 2024 |