Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis T Nakatsuji, TH Chen, S Narala, KA Chun, AM Two, T Yun, F Shafiq, ... Science translational medicine 9 (378), eaah4680, 2017 | 1134 | 2017 |
Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury Y Lai, A Di Nardo, T Nakatsuji, A Leichtle, Y Yang, AL Cogen, ZR Wu, ... Nature medicine 15 (12), 1377-1382, 2009 | 873 | 2009 |
Antimicrobial peptides: old molecules with new ideas T Nakatsuji, RL Gallo Journal of investigative dermatology 132 (3), 887-895, 2012 | 553 | 2012 |
The microbiome extends to subepidermal compartments of normal skin T Nakatsuji, HI Chiang, SB Jiang, H Nagarajan, K Zengler, RL Gallo Nature communications 4 (1), 1431, 2013 | 522 | 2013 |
Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris T Nakatsuji, MC Kao, JY Fang, CC Zouboulis, L Zhang, RL Gallo, ... Journal of investigative dermatology 129 (10), 2480-2488, 2009 | 507 | 2009 |
Microbial symbiosis with the innate immune defense system of the skin RL Gallo, T Nakatsuji Journal of Investigative Dermatology 131 (10), 1974-1980, 2011 | 488 | 2011 |
TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes K Yamasaki, K Kanada, DT Macleod, AW Borkowski, S Morizane, ... Journal of Investigative Dermatology 131 (3), 688-697, 2011 | 453 | 2011 |
Ultraviolet radiation damages self noncoding RNA and is detected by TLR3 JJ Bernard, C Cowing-Zitron, T Nakatsuji, B Muehleisen, J Muto, ... Nature medicine 18 (8), 1286-1290, 2012 | 449 | 2012 |
Molecular cartography of the human skin surface in 3D A Bouslimani, C Porto, CM Rath, M Wang, Y Guo, A Gonzalez, ... Proceedings of the National Academy of Sciences 112 (17), E2120-E2129, 2015 | 411 | 2015 |
Staphylococcus aureus exploits epidermal barrier defects in atopic dermatitis to trigger cytokine expression T Nakatsuji, TH Chen, AM Two, KA Chun, S Narala, RS Geha, TR Hata, ... Journal of Investigative Dermatology 136 (11), 2192-2200, 2016 | 407 | 2016 |
Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating β-defensin-2 expression T Nakatsuji, MC Kao, L Zhang, CC Zouboulis, RL Gallo, CM Huang The Journal of investigative dermatology 130 (4), 985, 2009 | 296 | 2009 |
A commensal strain of Staphylococcus epidermidis protects against skin neoplasia T Nakatsuji, TH Chen, AM Butcher, LL Trzoss, SJ Nam, KT Shirakawa, ... Science Advances 4 (2), eaao4502, 2018 | 289 | 2018 |
The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes D Yang, D Pornpattananangkul, T Nakatsuji, M Chan, D Carson, ... Biomaterials 30 (30), 6035-6040, 2009 | 286 | 2009 |
Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis MR Williams, SK Costa, LS Zaramela, S Khalil, DA Todd, HL Winter, ... Science translational medicine 11 (490), eaat8329, 2019 | 273 | 2019 |
Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial T Nakatsuji, TR Hata, Y Tong, JY Cheng, F Shafiq, AM Butcher, SS Salem, ... Nature medicine 27 (4), 700-709, 2021 | 241 | 2021 |
IL-4Rα blockade by dupilumab decreases Staphylococcus aureus colonization and increases microbial diversity in atopic dermatitis C Callewaert, T Nakatsuji, R Knight, T Kosciolek, A Vrbanac, P Kotol, ... Journal of Investigative Dermatology 140 (1), 191-202. e7, 2020 | 198 | 2020 |
Staphylococcus aureus induces increased serine protease activity in keratinocytes MR Williams, T Nakatsuji, JA Sanford, AF Vrbanac, RL Gallo Journal of Investigative Dermatology 137 (2), 377-384, 2017 | 173 | 2017 |
Crustacean molt-inhibiting hormone: structure, function, and cellular mode of action T Nakatsuji, CY Lee, RD Watson Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2009 | 165 | 2009 |
Histone H4 is a major component of the antimicrobial action of human sebocytes DY Lee, CM Huang, T Nakatsuji, D Thiboutot, SA Kang, M Monestier, ... Journal of investigative dermatology 129 (10), 2489-2496, 2009 | 163 | 2009 |
The role of the skin microbiome in atopic dermatitis T Nakatsuji, RL Gallo Annals of Allergy, Asthma & Immunology 122 (3), 263-269, 2019 | 161 | 2019 |