| Time-restricted eating to prevent and manage chronic metabolic diseases A Chaix, ENC Manoogian, GC Melkani, S Panda Annual review of nutrition 39 (1), 291-315, 2019 | 399 | 2019 |
| Time-restricted feeding attenuates age-related cardiac decline in Drosophila S Gill, HD Le, GC Melkani, S Panda Science 347 (6227), 1265-1269, 2015 | 288 | 2015 |
| Time‐restricted feeding for prevention and treatment of cardiometabolic disorders GC Melkani, S Panda The Journal of physiology 595 (12), 3691-3700, 2017 | 187 | 2017 |
| Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption JE Villanueva, C Livelo, AS Trujillo, S Chandran, B Woodworth, ... Nature communications 10 (1), 2700, 2019 | 133 | 2019 |
| Huntington's Disease Induced Cardiac Amyloidosis Is Reversed by Modulating Protein Folding and Oxidative Stress Pathways in the Drosophila Heart GC Melkani, AS Trujillo, R Ramos, R Bodmer, SI Bernstein, K Ocorr PLoS genetics 9 (12), e1004024, 2013 | 97 | 2013 |
| Using Drosophila as an integrated model to study mild repetitive traumatic brain injury A Barekat, A Gonzalez, RE Mauntz, RW Kotzebue, B Molina, ... Scientific reports 6 (1), 25252, 2016 | 88 | 2016 |
| The UNC-45 Chaperone Is Critical for Establishing Myosin-Based Myofibrillar Organization and Cardiac Contractility in the Drosophila Heart Model GC Melkani, R Bodmer, K Ocorr, SI Bernstein PloS one 6 (7), e22579, 2011 | 69 | 2011 |
| The UNC-45 myosin chaperone: from worms to flies to vertebrates CF Lee, GC Melkani, SI Bernstein International review of cell and molecular biology 313, 103-144, 2014 | 68 | 2014 |
| αB-crystallin maintains skeletal muscle myosin enzymatic activity and prevents its aggregation under heat-shock stress GC Melkani, A Cammarato, SI Bernstein Journal of molecular biology 358 (3), 635-645, 2006 | 67 | 2006 |
| When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging MM Mihaylova, A Chaix, M Delibegovic, JJ Ramsey, J Bass, G Melkani, ... Cell metabolism 35 (7), 1114-1131, 2023 | 51 | 2023 |
| Increasing autophagy and blocking Nrf2 suppress laminopathy‐induced age‐dependent cardiac dysfunction and shortened lifespan S Bhide, AS Trujillo, MT O'Connor, GH Young, DE Cryderman, ... Aging cell 17 (3), e12747, 2018 | 49 | 2018 |
| Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability CF Lee, GC Melkani, Q Yu, JA Suggs, WA Kronert, Y Suzuki, L Hipolito, ... Journal of cell science 124 (5), 699-705, 2011 | 48 | 2011 |
| Prolonged cross-bridge binding triggers muscle dysfunction in a Drosophila model of myosin-based hypertrophic cardiomyopathy WA Kronert, KM Bell, MC Viswanathan, GC Melkani, AS Trujillo, A Huang, ... Elife 7, e38064, 2018 | 41 | 2018 |
| Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase GC Melkani, CF Lee, A Cammarato, SI Bernstein Biochemical and biophysical research communications 396 (2), 317-322, 2010 | 39 | 2010 |
| The relay/converter interface influences hydrolysis of ATP by skeletal muscle myosin II MJ Bloemink, GC Melkani, SI Bernstein, MA Geeves Journal of Biological Chemistry 291 (4), 1763-1773, 2016 | 29 | 2016 |
| TRiC/CCT chaperonins are essential for maintaining myofibril organization, cardiac physiological rhythm, and lifespan GC Melkani, S Bhide, A Han, J Vyas, C Livelo, R Bodmer, SI Bernstein FEBS letters 591 (21), 3447-3458, 2017 | 28 | 2017 |
| The ATPase activity of GroEL is supported at high temperatures by divalent cations that stabilize its structure GC Melkani, G Zardeneta, JA Mendoza Biometals 16, 479-484, 2003 | 25 | 2003 |
| Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models C Livelo, Y Guo, F Abou Daya, V Rajasekaran, S Varshney, HD Le, ... Nature communications 14 (1), 949, 2023 | 22 | 2023 |
| Huntington’s disease-induced cardiac disorders affect multiple cellular pathways GC Melkani Reactive oxygen species (Apex, NC) 2 (5), 325, 2016 | 22 | 2016 |
| Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness Y Wang, GC Melkani, JA Suggs, A Melkani, WA Kronert, A Cammarato, ... Molecular biology of the cell 23 (11), 2057-2065, 2012 | 22 | 2012 |