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| Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3 JW Xianzhou Song†, Jianwei Chen†, Mingkun Zhao, Chengwei Zhang, Yang Yu ... Proceedings of the National Academy of Sciences 113 (18), 4970-4975, 2016 | 89 | 2016 |
| Steroid receptor coactivator-3 (SRC-3/AIB1) as a novel therapeutic target in triple negative breast cancer and its inhibition with a phospho-bufalin prodrug X Song, C Zhang, M Zhao, H Chen, X Liu, J Chen, DM Lonard, L Qin, J Xu, ... PloS one 10 (10), e0140011, 2015 | 42 | 2015 |
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| Targeting triple-negative breast cancer by a novel proteolysis targeting chimera degrader of enhancer of zeste homolog 2 B Dale, C Anderson, KS Park, HU Kaniskan, A Ma, Y Shen, C Zhang, ... ACS Pharmacology & Translational Science 5 (7), 491-507, 2022 | 32 | 2022 |
| Development of a Triazole Class of Highly Potent Porcn Inhibitors L You, C Zhang, N Yarravarapu, L Morlock, XL Wang, L Zhang, ... Bioorg. Med. Chem. Lett. 26, 5891, 2016 | 24 | 2016 |
| SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma X Song, H Chen, C Zhang, Y Yu, Z Chen, H Liang, II George Van Buren, ... Cancer Letters 442, 310-319, 2019 | 22 | 2019 |
| Stereoselective fatty acylation is essential for the release of lipidated WNT proteins from the acyltransferase Porcupine (PORCN) R Tuladhar, N Yarravarapu, Y Ma, C Zhang, J Herbert, J Kim, C Chen, ... Journal of Biological Chemistry 294 (16), 6273-6282, 2019 | 20 | 2019 |
| Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader X Yu, J Wang, W Gong, A Ma, Y Shen, C Zhang, X Liu, L Cai, J Liu, ... Oncogene 42 (13), 994-1009, 2023 | 15 | 2023 |
| Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles C Zhang, L You, C Chen Molecules 20, 1268, 2016 | 9 | 2016 |
| Compositions and Methods for Treating ALK-Mediated Cancer J Jin, Y Xiong, J Liu, C Zhang, X Han, H Chen, P Wang US Patent App. 16/769,326, 2021 | 6 | 2021 |
| Tropomyosin receptor kinase (trk) degradation compounds and methods of use J Liu, MB Plewe, J Wang, X Han, L Chen, C Zhang US Patent App. 17/904,822, 2023 | 2 | 2023 |
| Compounds and methods of treating cancers J Liu, MB Plewe, J Wang, X Han, L Chen, T Yang, C Zhang US Patent App. 18/248,035, 2024 | 1 | 2024 |
| Disubstituted and trisubstituted 1, 2, 3-triazoles as Wnt inhibitors N Yarravarapu, C Chen, L Lum, YOU Lin, C Zhang, X Wang, L Zhang US Patent 10,793,544, 2020 | 1 | 2020 |
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