Copper-boryl mediated organic synthesis D Hemming, R Fritzemeier, SA Westcott, WL Santos, PG Steel Chemical Society Reviews 47 (19), 7477-7494, 2018 | 279 | 2018 |
Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane BM Kenwood, JL Weaver, A Bajwa, IK Poon, FL Byrne, BA Murrow, ... Molecular metabolism 3 (2), 114-123, 2014 | 263 | 2014 |
Structure of a DNA glycosylase searching for lesions A Banerjee, WL Santos, GL Verdine Science 311 (5764), 1153-1157, 2006 | 235 | 2006 |
First-row d-block element-catalyzed carbon–boron bond formation and related processes SK Bose, L Mao, L Kuehn, U Radius, J Nekvinda, WL Santos, SA Westcott, ... Chemical Reviews 121 (21), 13238-13341, 2021 | 221 | 2021 |
sp2−sp3 Hybridized Mixed Diboron: Synthesis, Characterization, and Copper-Catalyzed β-Boration of α,β-Unsaturated Conjugated Compounds M Gao, SB Thorpe, WL Santos Organic Letters 11 (15), 3478-3481, 2009 | 175 | 2009 |
Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent SB Hooks, WL Santos, DS Im, CE Heise, TL Macdonald, KR Lynch Journal of Biological Chemistry 276 (7), 4611-4621, 2001 | 164 | 2001 |
Small molecule mitochondrial uncouplers and their therapeutic potential: miniperspective ES Childress, SJ Alexopoulos, KL Hoehn, WL Santos Journal of Medicinal Chemistry 61 (11), 4641-4655, 2017 | 147 | 2017 |
Structure and Reactivity of a Preactivated sp2–sp3 Diboron Reagent: Catalytic Regioselective Boration of α,β-Unsaturated Conjugated Compounds M Gao, SB Thorpe, C Kleeberg, C Slebodnick, TB Marder, WL Santos The Journal of Organic Chemistry 76 (10), 3997-4007, 2011 | 134 | 2011 |
Activity of 2-substituted lysophosphatidic acid (LPA) analogs at LPA receptors: discovery of a LPA1/LPA3 receptor antagonist CE Heise, WL Santos, AM Schreihofer, BH Heasley, YV Mukhin, ... Molecular pharmacology 60 (6), 1173-1180, 2001 | 134 | 2001 |
Regio-and stereoselective copper-catalyzed β-borylation of allenoates by a preactivated diboron SB Thorpe, X Guo, WL Santos Chemical Communications 47 (1), 424-426, 2011 | 120 | 2011 |
Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate Y Kharel, M Raje, M Gao, AM Gellett, JL Tomsig, KR Lynch, WL Santos Biochemical Journal 447 (1), 149-157, 2012 | 112 | 2012 |
Drugging sphingosine kinases WL Santos, KR Lynch ACS chemical biology 10 (1), 225-233, 2015 | 99 | 2015 |
A method for the deprotection of alkylpinacolyl boronate esters J Sun, MT Perfetti, WL Santos The Journal of organic chemistry 76 (9), 3571-3575, 2011 | 97 | 2011 |
Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice SJ Alexopoulos, SY Chen, AE Brandon, JM Salamoun, FL Byrne, ... Nature communications 11 (1), 2397, 2020 | 95 | 2020 |
Integration requires a specific interaction of the donor DNA terminal 5′-cytosine with glutamine 148 of the HIV-1 integrase flexible loop AA Johnson, W Santos, GCG Pais, C Marchand, R Amin, TR Burke, ... Journal of Biological Chemistry 281 (1), 461-467, 2006 | 95 | 2006 |
Unexpected copper (II) catalysis: Catalytic amine base promoted β-borylation of α, β-unsaturated carbonyl compounds in water SB Thorpe, JA Calderone, WL Santos Organic Letters 14 (7), 1918-1921, 2012 | 93 | 2012 |
Structure− activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of sphK1-and sphK2-selective inhibitors NN Patwardhan, EA Morris, Y Kharel, MR Raje, M Gao, JL Tomsig, ... Journal of medicinal chemistry 58 (4), 1879-1899, 2015 | 81 | 2015 |
Substrate‐Assisted, Transition‐Metal‐Free Diboration of Alkynamides with Mixed Diboron: Regio‐ and Stereoselective Access to trans‐1,2‐Vinyldiboronates A Verma, RF Snead, Y Dai, C Slebodnick, Y Yang, H Yu, F Yao, ... Angewandte Chemie 129 (18), 5193-5197, 2017 | 75 | 2017 |
Sphingosine kinase 2 inhibition and blood sphingosine 1-phosphate levels Y Kharel, EA Morris, MD Congdon, SB Thorpe, JL Tomsig, WL Santos, ... The Journal of pharmacology and experimental therapeutics 355 (1), 23-31, 2015 | 75 | 2015 |
Copper(II)‐Catalyzed Silylation of Activated Alkynes in Water: Diastereodivergent Access to E‐ or Z‐β‐Silyl‐α,β‐Unsaturated Carbonyl and Carboxyl Compounds JA Calderone, WL Santos Angewandte Chemie International Edition 53 (16), 4154-4158, 2014 | 75 | 2014 |