| Design of SARS-CoV-2 PLpro inhibitors for COVID-19 antiviral therapy leveraging binding cooperativity Z Shen, K Ratia, L Cooper, D Kong, H Lee, Y Kwon, Y Li, S Alqarni, ... Journal of medicinal chemistry 65 (4), 2940-2955, 2021 | 171 | 2021 |
| Strategies for targeting undruggable targets G Zhang, J Zhang, Y Gao, Y Li, Y Li Expert Opinion on Drug Discovery 17 (1), 55-69, 2022 | 72 | 2022 |
| Design and synthesis of basic selective estrogen receptor degraders for endocrine therapy resistant breast cancer Y Lu, LM Gutgesell, R Xiong, J Zhao, Y Li, CI Rosales, M Hollas, Z Shen, ... Journal of medicinal chemistry 62 (24), 11301-11323, 2019 | 41 | 2019 |
| Sequential DNA-encoded building block fusion for the construction of polysubstituted pyrazoline core libraries J Zhang, X Li, H Wei, Y Li, G Zhang, Y Li Organic Letters 23 (21), 8429-8433, 2021 | 34 | 2021 |
| DNA-Compatible ortho-Phthalaldehyde (OPA)-Mediated 2-Substituted Isoindole Core Formation and Applications Q Nie, X Fang, C Liu, G Zhang, X Fan, Y Li, Y Li The Journal of Organic Chemistry 87 (5), 2551-2558, 2022 | 31 | 2022 |
| In-solution direct oxidative coupling for the integration of sulfur/selenium into DNA-encoded chemical libraries S Yang, G Zhao, Y Gao, Y Sun, G Zhang, X Fan, Y Li, Y Li Chemical Science 13 (9), 2604-2613, 2022 | 30 | 2022 |
| Novel pyrrolopyridone bromodomain and extra-terminal motif (BET) inhibitors effective in endocrine-resistant ER+ breast cancer with acquired resistance to fulvestrant and … Y Li, J Zhao, LM Gutgesell, Z Shen, K Ratia, K Dye, O Dubrovskyi, H Zhao, ... Journal of medicinal chemistry 63 (13), 7186-7210, 2020 | 30 | 2020 |
| XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer DR Principe, R Xiong, Y Li, TND Pham, SD Kamath, O Dubrovskyi, ... Proceedings of the National Academy of Sciences 119 (4), e2116764119, 2022 | 29 | 2022 |
| Visible light-promoted divergent benzoheterocyclization from aldehydes for DNA-encoded chemical libraries X Fang, Y Wang, P He, H Liao, G Zhang, Y Li, Y Li Organic Letters 24 (17), 3291-3296, 2022 | 26 | 2022 |
| Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry A Schafer, R Xiong, L Cooper, R Nowar, H Lee, Y Li, BE Ramirez, ... PLoS Pathogens 17 (2), e1009312, 2021 | 26 | 2021 |
| Antimony salt-promoted cyclization facilitating on-DNA syntheses of dihydroquinazolinone derivatives and its applications Q Nie, J Sun, X Fang, X He, F Xiong, G Zhang, Y Li, Y Li Chinese Chemical Letters 34 (8), 108132, 2023 | 23 | 2023 |
| Development of 3‐Phenyl‐N‐(2‐(3‐phenylureido)ethyl)‐thiophene‐2‐sulfonamide Compounds as Inhibitors of Antiapoptotic Bcl‐2 Family Proteins C Yang, S Chen, M Zhou, Y Li, Y Li, Z Zhang, Z Liu, Q Ba, J Li, H Wang, ... ChemMedChem 9 (7), 1436-1452, 2014 | 23 | 2014 |
| Efficient synthesis of baicalin and its analogs YF Li, B Yu, JS Sun, RX Wang Tetrahedron Letters 56 (24), 3816-3819, 2015 | 22 | 2015 |
| Efficient synthesis of rottlerin and its two subunits Y Li, B Yu, R Wang Tetrahedron Letters 57 (17), 1856-1859, 2016 | 21 | 2016 |
| Unexpected cyclization product discovery from the photoinduced bioconjugation chemistry between Tetrazole and Amine J Zhang, J Liu, X Li, Y Ju, Y Li, G Zhang, Y Li Journal of the American Chemical Society 146 (3), 2122-2131, 2024 | 20 | 2024 |
| Screening and reverse-engineering of estrogen receptor ligands as potent pan-filovirus inhibitors L Cooper, A Schafer, Y Li, H Cheng, B Medegan Fagla, Z Shen, R Nowar, ... Journal of medicinal chemistry 63 (19), 11085-11099, 2020 | 20 | 2020 |
| Aryl diazonium intermediates enable mild DNA-compatible C–C bond formation for medicinally relevant combinatorial library synthesis X Li, J Zhang, C Liu, J Sun, Y Li, G Zhang, Y Li Chemical Science 13 (44), 13100-13109, 2022 | 18 | 2022 |
| DNA-compatible synthesis of α, β-epoxyketones for DNA-encoded chemical libraries Y Gao, G Zhao, P He, G Zhang, Y Li, Y Li Bioconjugate Chemistry 33 (1), 105-110, 2021 | 16 | 2021 |
| DNA-compatible diversification of indole π-activated alcohols via a direct dehydrative coupling strategy S Zhong, X Fang, Y Wang, G Zhang, Y Li, Y Li Organic Letters 24 (4), 1022-1026, 2022 | 14 | 2022 |
| Multicomponent DNA-compatible synthesis of an annelated benzodiazepine scaffold for focused chemical libraries G Zhao, H Wang, J Luo, X He, F Xiong, Y Li, G Zhang, Y Li Organic Letters 25 (4), 665-670, 2023 | 13 | 2023 |
