| The pro-and anti-inflammatory properties of the cytokine interleukin-6 J Scheller, A Chalaris, D Schmidt-Arras, S Rose-John Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (5), 878-888, 2011 | 4096 | 2011 |
| IL-6 pathway in the liver: from physiopathology to therapy D Schmidt-Arras, S Rose-John Journal of hepatology 64 (6), 1403-1415, 2016 | 909 | 2016 |
| Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes C Choudhary, JV Olsen, C Brandts, J Cox, PNG Reddy, FD Böhmer, ... Molecular cell 36 (2), 326-339, 2009 | 382 | 2009 |
| A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis T Schwerd, SRF Twigg, D Aschenbrenner, S Manrique, KA Miller, ... Journal of Experimental Medicine 214 (9), 2547-2562, 2017 | 204 | 2017 |
| Tyrosine phosphorylation regulates maturation of receptor tyrosine kinases DE Schmidt-Arras, A Böhmer, B Markova, C Choudhary, H Serve, ... Molecular and cellular biology 25 (9), 3690-3703, 2005 | 201 | 2005 |
| IL‐6 trans‐signaling is essential for the development of hepatocellular carcinoma in mice J Bergmann, M Müller, N Baumann, M Reichert, C Heneweer, J Bolik, ... Hepatology 65 (1), 89-103, 2017 | 165 | 2017 |
| Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10 J Prox, M Willenbrock, S Weber, T Lehmann, D Schmidt-Arras, ... Cellular and Molecular Life Sciences 69, 2919-2932, 2012 | 144 | 2012 |
| Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality D Schmidt-Arras, SA Böhmer, S Koch, JP Müller, L Blei, H Cornils, ... Blood, The Journal of the American Society of Hematology 113 (15), 3568-3576, 2009 | 125 | 2009 |
| Flt3 receptor tyrosine kinase as a drug target in leukemia D Schmidt-Arras, J Schwable, FD Bohmer, H Serve Current pharmaceutical design 10 (16), 1867-1883, 2004 | 87 | 2004 |
| Microbiomarkers in inflammatory bowel diseases: caveats come with caviar F Sommer, MC Rühlemann, C Bang, M Höppner, A Rehman, C Kaleta, ... Gut 66 (10), 1734-1738, 2017 | 77 | 2017 |
| ADAM17 is required for EGF-R–induced intestinal tumors via IL-6 trans-signaling S Schmidt, N Schumacher, J Schwarz, S Tangermann, L Kenner, ... Journal of Experimental Medicine 215 (4), 1205-1225, 2018 | 74 | 2018 |
| Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17 J Schwarz, C Broder, A Helmstetter, S Schmidt, I Yan, M Müller, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (12), 3355-3367, 2013 | 68 | 2013 |
| Degradome of soluble ADAM10 and ADAM17 metalloproteases F Scharfenberg, A Helbig, M Sammel, J Benzel, U Schlomann, F Peters, ... Cellular and Molecular Life Sciences 77, 331-350, 2020 | 66 | 2020 |
| Hepatocytes contribute to immune regulation in the liver by activation of the Notch signaling pathway in T cells S Burghardt, A Erhardt, B Claass, S Huber, G Adler, T Jacobs, A Chalaris, ... The Journal of Immunology 191 (11), 5574-5582, 2013 | 63 | 2013 |
| Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis J Bolik, F Krause, M Stevanovic, M Gandraß, I Thomsen, SS Schacht, ... Journal of experimental medicine 219 (1), e20201039, 2021 | 59 | 2021 |
| Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding J Schwarz, S Schmidt, O Will, T Koudelka, K Köhler, M Boss, B Rabe, ... Journal of Biological Chemistry 289 (5), 3080-3093, 2014 | 58 | 2014 |
| Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease A Chalaris, D Schmidt-Arras, K Yamamoto, S Rose-John Digestive diseases 30 (5), 492-499, 2012 | 57 | 2012 |
| Cellular inhibition of protein tyrosine phosphatase 1B by uncharged thioxothiazolidinone derivatives M Stuible, L Zhao, I Aubry, D Schmidt‐Arras, FD Böhmer, CJ Li, ... Chembiochem 8 (2), 179-186, 2007 | 47 | 2007 |
| Cyclosporin A Treatment of Leishmania donovani Reveals Stage-Specific Functions of Cyclophilins in Parasite Proliferation and Viability WL Yau, T Blisnick, JF Taly, M Helmer-Citterich, C Schiene-Fischer, ... PLoS neglected tropical diseases 4 (6), e729, 2010 | 46 | 2010 |
| Gut microbiota shape ‘inflamm-ageing’cytokines and account for age-dependent decline in DNA damage repair A Guedj, Y Volman, A Geiger-Maor, J Bolik, N Schumacher, S Künzel, ... Gut 69 (6), 1064-1075, 2020 | 45 | 2020 |