Structural mechanisms of CFTR function and dysfunction TC Hwang, JT Yeh, J Zhang, YC Yu, HI Yeh, S Destefano Journal of General Physiology 150 (4), 539-570, 2018 | 147 | 2018 |
Identifying the molecular target sites for CFTR potentiators GLPG1837 and VX-770 HI Yeh, L Qiu, Y Sohma, K Conrath, X Zou, TC Hwang Journal of General Physiology 151 (7), 912-928, 2019 | 73 | 2019 |
A common mechanism for CFTR potentiators HI Yeh, Y Sohma, K Conrath, TC Hwang Journal of General Physiology 149 (12), 1105-1118, 2017 | 69 | 2017 |
Modulation of CFTR gating by permeant ions HI Yeh, JT Yeh, TC Hwang Journal of General Physiology 145 (1), 47-60, 2015 | 52 | 2015 |
Functional stability of CFTR depends on tight binding of ATP at its degenerate ATP‐binding site HI Yeh, YC Yu, PL Kuo, CK Tsai, HT Huang, TC Hwang The Journal of physiology 599 (20), 4625-4642, 2021 | 12 | 2021 |
CFTR modulators: from mechanism to targeted therapeutics HI Yeh, KJ Sutcliffe, DN Sheppard, TC Hwang Anion Channels and Transporters, 219-247, 2022 | 7 | 2022 |
Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore X Gao, HI Yeh, Z Yang, C Fan, F Jiang, RJ Howard, E Lindahl, JC Kappes, ... Nature Communications 15 (1), 6668, 2024 | 2 | 2024 |
In vitro assessment of triple combination therapy for the most common disease-associated mutation in cystic fibrosis HI Yeh, TC Hwang European Respiratory Journal 59 (2), 2022 | 1 | 2022 |
314 Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore X Gao, H Yeh, Z Yang, C Fan, F Jiang, R Howard, E Lindahl, J Kappes, ... Journal of Cystic Fibrosis 23, S167, 2024 | | 2024 |
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Targeted Therapeutics for Cystic Fibrosis DF Veselu, HI Yeh, M Rodrat, JD Bradbury, Y Manzanares Fornies, H Li, ... Ion Channels as Targets in Drug Discovery, 239-284, 2024 | | 2024 |
Cystic Fibrosis and the CFTR Anion Channels HI Yeh, TC Hwang Textbook of Ion Channels Volume III, 173-188, 2023 | | 2023 |
MULTIPLE BINDING SITES FOR CFTR POTENTIATORS REVEALED BY SPECIES-DEPENDENT RESPONSES H Yeh, T Hwang PEDIATRIC PULMONOLOGY 54, S203-S203, 2019 | | 2019 |
Molecular mechanisms of action for CFTR potentiators HI Yeh University of Missouri--Columbia, 2019 | | 2019 |
RESPONSIVENESS TO CFTR POTENTIATOR DEPENDS ON INTACT R347-D924 INTERACTION H Yeh, K Conrath, T Hwang PEDIATRIC PULMONOLOGY 53, 153-153, 2018 | | 2018 |
Potentiation of CFTR Gating by an Energetically Additive Mechanism HI Yeh, JT Yeh, TC Hwang Biophysical Journal 108 (2), 19a, 2015 | | 2015 |
Non-Equilibrium Gating of CFTR Revealed by Nitrate as Charge Carriers JT Yeh, HI Yeh, TC Hwang Biophysical Journal 106 (2), 148a-149a, 2014 | | 2014 |