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The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells E Perucha, R Melchiotti, JA Bibby, W Wu, KS Frederiksen, CA Roberts, ... Nature communications 10 (1), 498, 2019 | 130 | 2019 |
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Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate JA Bibby, HA Purvis, T Hayday, A Chandra, K Okkenhaug, S Rosenzweig, ... Nature communications 11 (1), 3412, 2020 | 72 | 2020 |
Proteomic, biomechanical and functional analyses define neutrophil heterogeneity in systemic lupus erythematosus KR Bashant, AM Aponte, D Randazzo, PR Sangsari, AJT Wood, JA Bibby, ... Annals of the rheumatic diseases 80 (2), 209-218, 2021 | 61 | 2021 |
Systematic single-cell pathway analysis to characterize early T cell activation JA Bibby, D Agarwal, T Freiwald, N Kunz, NS Merle, EE West, P Singh, ... Cell reports 41 (8), 2022 | 47 | 2022 |
An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19 R McGregor, D Chauss, T Freiwald, B Yan, L Wang, E Nova-Lamperti, ... BioRxiv, 2020.07. 18.210161, 2020 | 31 | 2020 |
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Multi-color molecular visualization of signaling proteins reveals how C-terminal Src kinase nanoclusters regulate T cell receptor activation S Simoncelli, J Griffié, DJ Williamson, J Bibby, C Bray, R Zamoyska, ... Cell Reports 33 (12), 2020 | 21 | 2020 |
Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells F Clarke, CK Jordan, E Gutierrez-Martinez, JA Bibby, C Sanchez-Blanco, ... PLoS One 12 (10), e0186625, 2017 | 17 | 2017 |
Phosphatase PTPN22 regulates dendritic cell homeostasis and cdc2 dependent T cell responses HA Purvis, F Clarke, AB Montgomery, C Colas, JA Bibby, GH Cornish, ... Frontiers in immunology 11, 376, 2020 | 10 | 2020 |
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The immunogenicity of fractional intradermal doses of the inactivated poliovirus vaccine is associated with the size of the intradermal fluid bleb J Bibby, Y Saidu, A Umesi, N Moneke-Anyanwoke, AO Bashorun, ... Clinical Infectious Diseases 65 (5), 851-854, 2017 | 8 | 2017 |
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Systematic Single Cell Pathway Analysis (SCPA) reveals novel pathways engaged during early T cell activation JA Bibby, D Agarwal, T Freiwald, N Kunz, NS Merle, EE West, ... BioRxiv, 2022.02. 07.478807, 2022 | 2 | 2022 |
Multi-colour DNA-qPAINT reveals how Csk nano-clusters regulate T-cell receptor signalling S Simoncelli, J Griffié, DJ Williamson, J Bibby, C Bray, R Zamoyska, ... bioRxiv, 857516, 2019 | 2 | 2019 |
Cholesterol metabolism drives regulatory B cell function JA Bibby, HA Purvis, T Hayday, A Chandra, K Okkenhaug, M Wood, ... bioRxiv, 2020.01. 03.893982, 2020 | 1 | 2020 |
Dysregulation of T cell intrinsic C5aR2 activation causes uncontrolled inflammatory Th responses and autoinflammatory syndrome E West, N Merle, J Bibby, P Singh, J Rahman, T Hyrup Morgensen, ... The Journal of Immunology 212 (1_Supplement), 0526_5407-0526_5407, 2024 | | 2024 |