Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators D Landeira, S Sauer, R Poot, M Dvorkina, L Mazzarella, HF Jørgensen, ... Nature cell biology 12 (6), 618-624, 2010 | 356 | 2010 |
Tumor mutational burden quantification from targeted gene panels: major advancements and challenges L Fancello, S Gandini, PG Pelicci, L Mazzarella Journal for immunotherapy of cancer 7, 1-13, 2019 | 311 | 2019 |
Combination of hypoglycemia and metformin impairs tumor metabolic plasticity and growth by modulating the PP2A-GSK3β-MCL-1 axis M Elgendy, M Ciro, A Hosseini, J Weiszmann, L Mazzarella, E Ferrari, ... Cancer cell 35 (5), 798-815. e5, 2019 | 288 | 2019 |
Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis S Trabanelli, MF Chevalier, A Martinez-Usatorre, A Gomez-Cadena, ... Nature communications 8 (1), 593, 2017 | 214 | 2017 |
Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program M Hoogenkamp, M Lichtinger, H Krysinska, C Lancrin, D Clarke, ... Blood, The Journal of the American Society of Hematology 114 (2), 299-309, 2009 | 144 | 2009 |
Runx proteins regulate Foxp3 expression L Bruno, L Mazzarella, M Hoogenkamp, A Hertweck, BS Cobb, S Sauer, ... Journal of Experimental Medicine 206 (11), 2329-2337, 2009 | 109 | 2009 |
Epigenetic priming of a pre-B cell-specific enhancer through binding of Sox2 and Foxd3 at the ESC stage D Liber, R Domaschenz, PH Holmqvist, L Mazzarella, A Georgiou, ... Cell stem cell 7 (1), 114-126, 2010 | 104 | 2010 |
The evolving landscape of ‘next-generation’immune checkpoint inhibitors: A review L Mazzarella, BA Duso, D Trapani, C Belli, P D'Amico, E Ferraro, G Viale, ... European journal of cancer 117, 14-31, 2019 | 103 | 2019 |
Cetuximab for treating non-small cell lung cancer L Mazzarella, A Guida, G Curigliano Expert opinion on biological therapy 18 (4), 483-493, 2018 | 89 | 2018 |
Increased BMI correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the AIDA protocols M Breccia, L Mazzarella, V Bagnardi, D Disalvatore, G Loglisci, G Cimino, ... Blood, The Journal of the American Society of Hematology 119 (1), 49-54, 2012 | 87 | 2012 |
Meta-analysis of diagnostic performance of serological tests for SARS-CoV-2 antibodies up to 25 April 2020 and public health implications S Caini, F Bellerba, F Corso, A Díaz-Basabe, G Natoli, J Paget, F Facciotti, ... Eurosurveillance 25 (23), 2000980, 2020 | 81 | 2020 |
Obesity increases the incidence of distant metastases in oestrogen receptor-negative human epidermal growth factor receptor 2-positive breast cancer patients L Mazzarella, D Disalvatore, V Bagnardi, N Rotmensz, D Galbiati, ... European Journal of Cancer 49 (17), 3588-3597, 2013 | 79 | 2013 |
p53 loss in breast cancer leads to Myc activation, increased cell plasticity, and expression of a mitotic signature with prognostic value A Santoro, T Vlachou, L Luzi, G Melloni, L Mazzarella, E D’Elia, X Aobuli, ... Cell reports 26 (3), 624-638. e8, 2019 | 77 | 2019 |
Detection of clustered circulating tumour cells in early breast cancer I Krol, FD Schwab, R Carbone, M Ritter, S Picocci, ML De Marni, ... British journal of cancer 125 (1), 23-27, 2021 | 76 | 2021 |
Entinostat for the treatment of breast cancer D Trapani, A Esposito, C Criscitiello, L Mazzarella, M Locatelli, I Minchella, ... Expert opinion on investigational drugs 26 (8), 965-971, 2017 | 69 | 2017 |
Cytotoxic drugs for patients with breast cancer in the era of targeted treatment: back to the future? JT Ribeiro, LT Macedo, G Curigliano, L Fumagalli, M Locatelli, M Dalton, ... Annals of Oncology 23 (3), 547-555, 2012 | 60 | 2012 |
Why does obesity promote cancer? Epidemiology, biology, and open questions L Mazzarella ecancermedicalscience 9, 554, 2015 | 48 | 2015 |
Obesity is a risk factor for acute promyelocytic leukemia: evidence from population and cross-sectional studies and correlation with FLT3 mutations and polyunsaturated fatty … L Mazzarella, E Botteri, A Matthews, E Gatti, D Di Salvatore, V Bagnardi, ... Haematologica 105 (6), 1559, 2019 | 41 | 2019 |
DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes GEM Melloni, AGE Ogier, S de Pretis, L Mazzarella, M Pelizzola, ... Genome medicine 6, 1-13, 2014 | 40 | 2014 |
Machine learning-based reclassification of germline variants of unknown significance: The RENOVO algorithm V Favalli, G Tini, E Bonetti, G Vozza, A Guida, S Gandini, PG Pelicci, ... The American Journal of Human Genetics 108 (4), 682-695, 2021 | 39 | 2021 |