Endoglin promotes transforming growth factor β-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC NY Lee, B Ray, T How, GC Blobe Journal of Biological Chemistry 283 (47), 32527-32533, 2008 | 146 | 2008 |
The interaction of endoglin with β-arrestin2 regulates transforming growth factor-β-mediated ERK activation and migration in endothelial cells NY Lee, GC Blobe Journal of Biological Chemistry 282 (29), 21507-21517, 2007 | 116 | 2007 |
ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration BN Ray, NY Lee, T How, GC Blobe Carcinogenesis 31 (3), 435-441, 2010 | 90 | 2010 |
Multifaceted roles of TAK1 signaling in cancer H Mukhopadhyay, NY Lee Oncogene 39 (7), 1402-1413, 2020 | 86 | 2020 |
The type III TGF-β receptor suppresses breast cancer progression through GIPC-mediated inhibition of TGF-β signaling JD Lee, N Hempel, NY Lee, GC Blobe Carcinogenesis 31 (2), 175-183, 2010 | 81 | 2010 |
Endocytosis of the type III transforming growth factor-β (TGF-β) receptor through the clathrin-independent/lipid raft pathway regulates TGF-β signaling and receptor down-regulation EC Finger, NY Lee, H You, GC Blobe Journal of Biological Chemistry 283 (50), 34808-34818, 2008 | 69 | 2008 |
Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer A Serrao, LM Jenkins, AA Chumanevich, B Horst, J Liang, ML Gatza, ... Oncogene 37 (35), 4792-4808, 2018 | 66 | 2018 |
Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling S Kumar, CC Pan, JC Bloodworth, AB Nixon, C Theuer, DG Hoyt, NY Lee Oncogene 33 (30), 3970-3979, 2014 | 66 | 2014 |
GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment BL Worley, YS Kim, J Mardini, R Zaman, KE Leon, PG Vallur, ... Redox biology 25, 101051, 2019 | 62 | 2019 |
Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis NY Lee, C Golzio, CE Gatza, A Sharma, N Katsanis, GC Blobe Molecular biology of the cell 23 (13), 2412-2423, 2012 | 62 | 2012 |
Insulin induces microtubule stabilization and regulates the microtubule plus-end tracking protein network in adipocytes*[S] SS Parker, J Krantz, EA Kwak, NK Barker, CG Deer, NY Lee, ... Molecular & Cellular Proteomics 18 (7), 1363-1381, 2019 | 61 | 2019 |
TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth N Shah, S Kumar, N Zaman, CC Pan, JC Bloodworth, W Lei, JM Streicher, ... Nature communications 9 (1), 1696, 2018 | 59 | 2018 |
The transforming growth factor-β type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK) 3 and ALK6 receptors NY Lee, KC Kirkbride, RD Sheu, GC Blobe Molecular biology of the cell 20 (20), 4362-4370, 2009 | 58 | 2009 |
TGFβ signaling networks in ovarian cancer progression and plasticity A Kumari, Z Shonibare, M Monavarian, RC Arend, NY Lee, GJ Inman, ... Clinical & Experimental Metastasis 38, 139-161, 2021 | 57 | 2021 |
Activation of Mitofusin2 by Smad2-RIN1 complex during mitochondrial fusion S Kumar, CC Pan, N Shah, SE Wheeler, KR Hoyt, N Hempel, K Mythreye, ... Molecular cell 62 (4), 520-531, 2016 | 54 | 2016 |
Structure and dynamics of the epidermal growth factor receptor C‐terminal phosphorylation domain NY Lee, TL Hazlett, JG Koland Protein science 15 (5), 1142-1152, 2006 | 54 | 2006 |
Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells YS Kim, P Gupta Vallur, VM Jones, BL Worley, S Shimko, DH Shin, ... Oncogene 39 (8), 1619-1633, 2020 | 51 | 2020 |
Conformational changes accompany phosphorylation of the epidermal growth factor receptor C‐terminal domain NY Lee, JG Koland Protein science 14 (11), 2793-2803, 2005 | 45 | 2005 |
Endoglin regulation of Smad2 function mediates Beclin1 expression and endothelial autophagy CC Pan, S Kumar, N Shah, JC Bloodworth, LJAC Hawinkels, K Mythreye, ... Journal of Biological Chemistry 290 (24), 14884-14892, 2015 | 44 | 2015 |
Inhibin is a novel paracrine factor for tumor angiogenesis and metastasis MK Singh P, Jenkins LM, Horst B, Alers V, Pradhan S, Kaur P, Srivastava T ... Cancer Research 78 (11), 2978-2989, 2018 | 42 | 2018 |