| Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model TF Rogers, F Zhao, D Huang, N Beutler, A Burns, W He, O Limbo, C Smith, ... Science 369 (6506), 956-963, 2020 | 1408 | 2020 |
| Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair RS Williams, G Moncalian, JS Williams, Y Yamada, O Limbo, DS Shin, ... Cell 135 (1), 97-109, 2008 | 590 | 2008 |
| Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination O Limbo, C Chahwan, Y Yamada, RAM de Bruin, C Wittenberg, P Russell Molecular cell 28 (1), 134-146, 2007 | 424 | 2007 |
| Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair RS Williams, GE Dodson, O Limbo, Y Yamada, JS Williams, G Guenther, ... Cell 139 (1), 87-99, 2009 | 396 | 2009 |
| Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks P Langerak, E Mejia-Ramirez, O Limbo, P Russell PLoS genetics 7 (9), e1002271, 2011 | 291 | 2011 |
| ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair GJ Williams, RS Williams, JS Williams, G Moncalian, AS Arvai, O Limbo, ... Nature structural & molecular biology 18 (4), 423-431, 2011 | 177 | 2011 |
| ATP‐driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling RA Deshpande, GJ Williams, O Limbo, RS Williams, J Kuhnlein, JH Lee, ... The EMBO journal 33 (5), 482-500, 2014 | 165 | 2014 |
| Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance DG Mendoza-Cozatl, Z Zhai, TO Jobe, GZ Akmakjian, WY Song, O Limbo, ... Journal of Biological Chemistry 285 (52), 40416-40426, 2010 | 119 | 2010 |
| RNase H eliminates R‐loops that disrupt DNA replication but is nonessential for efficient DSB repair H Zhao, M Zhu, O Limbo, P Russell EMBO reports 19 (5), e45335, 2018 | 92 | 2018 |
| Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease P Zhou, G Song, H Liu, M Yuan, W He, N Beutler, X Zhu, VT Longping, ... Immunity 56 (3), 669-686. e7, 2023 | 91 | 2023 |
| Mre11 Nuclease Activity and Ctp1 Regulate Chk1 Activation by Rad3ATR and Tel1ATM Checkpoint Kinases at Double-Strand Breaks O Limbo, ME Porter-Goff, N Rhind, P Russell Molecular and cellular biology 31 (3), 573-583, 2011 | 66 | 2011 |
| Phosphorylation-regulated binding of Ctp1 to Nbs1 is critical for repair of DNA double-strand breaks GE Dodson, O Limbo, D Nieto, P Russell Cell cycle 9 (8), 1516-1522, 2010 | 38 | 2010 |
| BRCT domain interactions with phospho-histone H2A target Crb2 to chromatin at double-strand breaks and maintain the DNA damage checkpoint S Sofueva, LL Du, O Limbo, JS Williams, P Russell Molecular and cellular biology 30 (19), 4732-4743, 2010 | 36 | 2010 |
| EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart S Hambarde, CL Tsai, RK Pandita, A Bacolla, A Maitra, V Charaka, ... Molecular cell 81 (14), 2989-3006. e9, 2021 | 35 | 2021 |
| Mre11 complex links sister chromatids to promote repair of a collapsed replication fork M Zhu, H Zhao, O Limbo, P Russell Proceedings of the National Academy of Sciences 115 (35), 8793-8798, 2018 | 32 | 2018 |
| Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif L Wang, O Limbo, J Fei, L Chen, B Kim, J Luo, J Chong, RC Conaway, ... Proceedings of the National Academy of Sciences 111 (52), 18566-18571, 2014 | 30 | 2014 |
| Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins IS Khalek, RR Senji Laxme, YTK Nguyen, S Khochare, RN Patel, J Woehl, ... Science Translational Medicine 16 (735), eadk1867, 2024 | 29 | 2024 |
| Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair O Limbo, D Moiani, A Kertokalio, C Wyman, JA Tainer, P Russell Nucleic acids research 40 (22), 11435-11449, 2012 | 29 | 2012 |
| Brc1 promotes the focal accumulation and SUMO ligase activity of Smc5-Smc6 during replication stress M Oravcová, MC Gadaleta, M Nie, MC Reubens, O Limbo, P Russell, ... Molecular and cellular biology 39 (2), e00271-18, 2019 | 26 | 2019 |
| Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast S Cavero, O Limbo, P Russell PLoS genetics 6 (9), e1001138, 2010 | 26 | 2010 |
