Image-based multivariate profiling of drug responses from single cells LH Loo, LF Wu, SJ Altschuler Nature methods 4 (5), 445-453, 2007 | 388 | 2007 |
Global epidemiology and genetics of hepatocellular carcinoma MR Toh, EYT Wong, SH Wong, AWT Ng, LH Loo, PKH Chow, J Ngeow Gastroenterology 164 (5), 766-782, 2023 | 292 | 2023 |
Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization K Paul Friedman, M Gagne, LH Loo, P Karamertzanis, T Netzeva, ... Toxicological Sciences 173 (1), 202-225, 2020 | 194 | 2020 |
Prediction of drug-induced nephrotoxicity and injury mechanisms with human induced pluripotent stem cell-derived cells and machine learning methods K Kandasamy, JKC Chuah, R Su, P Huang, KG Eng, S Xiong, Y Li, ... Scientific reports 5 (1), 12337, 2015 | 124 | 2015 |
Heterogeneity in the physiological states and pharmacological responses of differentiating 3T3-L1 preadipocytes LH Loo, HJ Lin, DK Singh, KM Lyons, SJ Altschuler, LF Wu Journal of Cell Biology 187 (3), 375-384, 2009 | 87 | 2009 |
An approach for extensibly profiling the molecular states of cellular subpopulations LH Loo, HJ Lin, RJ Steininger III, Y Wang, LF Wu, SJ Altschuler Nature methods 6 (10), 759-765, 2009 | 82 | 2009 |
Choice of PD-L1 immunohistochemistry assay influences clinical eligibility for gastric cancer immunotherapy J Yeong, HYJ Lum, CB Teo, BKJ Tan, YH Chan, RYK Tay, JRE Choo, ... Gastric Cancer 25 (4), 741-750, 2022 | 79 | 2022 |
Large‐scale image‐based screening and profiling of cellular phenotypes N Bougen‐Zhukov, SY Loh, HK Lee, LH Loo Cytometry Part A 91 (2), 115-125, 2017 | 78 | 2017 |
High-throughput imaging-based nephrotoxicity prediction for xenobiotics with diverse chemical structures R Su, S Xiong, D Zink, LH Loo Archives of toxicology 90 (11), 2793-2808, 2016 | 67 | 2016 |
Supervised prediction of drug-induced nephrotoxicity based on interleukin-6 and-8 expression levels R Su, Y Li, D Zink, LH Loo BMC bioinformatics 15, 1-9, 2014 | 47 | 2014 |
cellXpress: a fast and user-friendly software platform for profiling cellular phenotypes D Laksameethanasan, RZ Tan, GWL Toh, LH Loo BMC bioinformatics 14, 1-12, 2013 | 36 | 2013 |
Quantitative protein localization signatures reveal an association between spatial and functional divergences of proteins LH Loo, D Laksameethanasan, YL Tung PLoS computational biology 10 (3), e1003504, 2014 | 32 | 2014 |
Building predictive in vitro pulmonary toxicity assays using high-throughput imaging and artificial intelligence JYJ Lee, JA Miller, S Basu, TZV Kee, LH Loo Archives of toxicology 92, 2055-2075, 2018 | 30 | 2018 |
Emerging technologies for food and drug safety W Slikker Jr, TA de Souza Lima, D Archella, JB de Silva Junior, ... Regulatory Toxicology and Pharmacology 98, 115-128, 2018 | 28 | 2018 |
A case study with triazole fungicides to explore practical application of next-generation hazard assessment methods for human health LTM van der Ven, E Rorije, RC Sprong, D Zink, R Derr, G Hendriks, ... Chemical research in toxicology 33 (3), 834-848, 2020 | 26 | 2020 |
Apparatus and method for removing non-discriminatory indices of an indexed dataset LH Loo, L Hrebien, M Kam US Patent 8,010,296, 2011 | 23 | 2011 |
Quantification of the Effects of Perturbations on Biological Samples SJ Altschuler, LH Loo, LF Wu US Patent App. 11/673,910, 2008 | 18 | 2008 |
Leveraging advances in immunopathology and artificial intelligence to analyze in vitro tumor models in composition and space TKM Leong, WS Lo, WEZ Lee, B Tan, XZ Lee, LWJN Lee, JYJ Lee, ... Advanced drug delivery reviews 177, 113959, 2021 | 14 | 2021 |
Virtual screening of potentially endocrine-disrupting chemicals against nuclear receptors and its application to identify PPARγ-bound fatty acids CK Jaladanki, Y He, LN Zhao, S Maurer-Stroh, LH Loo, H Song, H Fan Archives of Toxicology 95, 355-374, 2021 | 14 | 2021 |
Cooperative multi-agent constellation formation under sensing and communication constraints LH Loo, E Lin, M Kam, P Varshney Cooperative Control and Optimization, 143-169, 2002 | 14 | 2002 |