Dramatic rise in plasma viremia after CD8+ T cell depletion in simian immunodeficiency virus–infected macaques X Jin, DE Bauer, SE Tuttleton, S Lewin, A Gettie, J Blanchard, CE Irwin, ... Journal of Experimental Medicine 189 (6), 991-998, 1999 | 1824 | 1999 |
The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy B Ramratnam, JE Mittler, L Zhang, D Boden, A Hurley, F Fang, ... Nature medicine 6 (1), 82-85, 2000 | 574 | 2000 |
Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis B Ramratnam, S Bonhoeffer, J Binley, A Hurley, L Zhang, JE Mittler, ... The Lancet 354 (9192), 1782-1785, 1999 | 568 | 1999 |
A replication clock for Mycobacterium tuberculosis WP Gill, NS Harik, MR Whiddon, RP Liao, JE Mittler, DR Sherman Nature medicine 15 (2), 211-214, 2009 | 417 | 2009 |
Influence of delayed viral production on viral dynamics in HIV-1 infected patients JE Mittler, B Sulzer, AU Neumann, AS Perelson Mathematical biosciences 152 (2), 143-163, 1998 | 386 | 1998 |
Regional isolation drives bacterial diversification within cystic fibrosis lungs P Jorth, BJ Staudinger, X Wu, KB Hisert, H Hayden, J Garudathri, ... Cell host & microbe 18 (3), 307-319, 2015 | 343 | 2015 |
EVOLUTIONARY ADAPTATION TO TEMPERATURE. I. FITNESS RESPONSES OF ESCHERICHIA COLI TO CHANGES IN ITS THERMAL ENVIRONMENT AF Bennett, RE Lenski, JE Mittler Evolution 46 (1), 16-30, 1992 | 330 | 1992 |
The directed mutation controversy and neo-Darwinism RE Lenski, JE Mittler Science 259 (5092), 188-194, 1993 | 315 | 1993 |
Host-parasite coexistence: the role of spatial refuges in stabilizing bacteria-phage interactions SJ Schrag, JE Mittler The American Naturalist 148 (2), 348-377, 1996 | 204 | 1996 |
Viral dynamics in primary HIV-1 infection S Lindbäck, AC Karlsson, J Mittler, A Blaxhult, M Carlsson, G Briheim, ... Aids 14 (15), 2283-2291, 2000 | 189 | 2000 |
New data on excisions of Mu from E. coli MCS2 cast doubt on directed mutation hypothesis JE Mittler, RE Lenski Nature 344 (6262), 173-175, 1990 | 134 | 1990 |
Evolutionary indicators of human immunodeficiency virus type 1 reservoirs and compartments DC Nickle, MA Jensen, D Shriner, SJ Brodie, LM Frenkel, JE Mittler, ... Journal of virology 77 (9), 5540-5546, 2003 | 133 | 2003 |
Improved estimates for H1V-1 clearance rate and intracellular delay JE Mittler, M Markowitz, DD Ho, AS Perelson Aids 13 (11), 1415, 1999 | 130 | 1999 |
Acyl-homoserine lactone-dependent eavesdropping promotes competition in a laboratory co-culture model JR Chandler, S Heilmann, JE Mittler, EP Greenberg The ISME journal 6 (12), 2219-2228, 2012 | 117 | 2012 |
Effect of drug efficacy and the eclipse phase of the viral life cycle on estimates of HIV viral dynamic parameters PW Nelson, JE Mittler, AS Perelson JAIDS Journal of Acquired Immune Deficiency Syndromes 26 (5), 405-412, 2001 | 112 | 2001 |
Influence of Random Genetic Drift on Human Immunodeficiency Virus Type 1 env Evolution During Chronic Infection D Shriner, R Shankarappa, MA Jensen, DC Nickle, JE Mittler, ... Genetics 166 (3), 1155-1164, 2004 | 98 | 2004 |
Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (Norvir) monotherapy PS Eastman, J Mittler, R Kelso, C Gee, E Boyer, J Kolberg, M Urdea, ... Journal of virology 72 (6), 5154-5164, 1998 | 98 | 1998 |
Rate of HIV-1 decline following antiretroviral therapy is related to viral load at baseline and drug regimen DW Notermans, J Goudsmit, SA Danner, F De Wolf, AS Perelson, J Mittler Aids 12 (12), 1483-1490, 1998 | 97 | 1998 |
Selection for human immunodeficiency virus type 1 recombinants in a patient with rapid progression to AIDS SL Liu, JE Mittler, DC Nickle, TM Mulvania, D Shriner, AG Rodrigo, ... Journal of virology 76 (21), 10674-10684, 2002 | 92 | 2002 |
Construction of regulatory networks using expression time-series data of a genotyped population KY Yeung, KM Dombek, K Lo, JE Mittler, J Zhu, EE Schadt, ... Proceedings of the National Academy of Sciences 108 (48), 19436-19441, 2011 | 89 | 2011 |