Cikkek nyilvánosan hozzáférhető megbízással - Juerg SchwallerTovábbi információ
Sehol sem hozzáférhető: 5
Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia
C Dafflon, VJ Craig, H Mereau, J Gräsel, BS Engstler, G Hoffman, ...
Leukemia 31 (6), 1269-1277, 2017
Megbízások: Swiss National Science Foundation, Swiss Cancer Foundation
Dasatinib and navitoclax act synergistically to target NUP98-NSD1+/FLT3-ITD+ acute myeloid leukemia
JL Kivioja, A Thanasopoulou, A Kumar, M Kontro, B Yadav, MM Majumder, ...
Leukemia 33 (6), 1360-1372, 2019
Megbízások: Finnish Funding Agency for Innovation, Swiss Cancer League
Critical role of retinoid/rexinoid signaling in mediating transformation and therapeutic response of NUP98-RARG leukemia
JJ Qiu, BB Zeisig, S Li, W Liu, H Chu, Y Song, A Giordano, J Schwaller, ...
Leukemia 29 (5), 1153-1162, 2015
Megbízások: Cancer Research UK
Nuclear PIM1 confers resistance to rapamycin-impaired endothelial proliferation
T Walpen, I Kalus, J Schwaller, MA Peier, EJ Battegay
Biochemical and biophysical research communications 429 (1-2), 24-30, 2012
Megbízások: Swiss National Science Foundation
Learning from mouse models of MLL fusion gene-driven acute leukemia
J Schwaller
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms, 194550, 2020
Megbízások: Swiss National Science Foundation, Swiss Cancer League
Valahol hozzáférhető: 44
Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice
R Tiedt, H Hao-Shen, MA Sobas, R Looser, S Dirnhofer, J Schwaller, ...
Blood, The Journal of the American Society of Hematology 111 (8), 3931-3940, 2008
Megbízások: Swiss National Science Foundation
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
L Arranz, A Sánchez-Aguilera, D Martín-Pérez, J Isern, X Langa, ...
Nature 512 (7512), 78-81, 2014
Megbízások: Swiss National Science Foundation, Howard Hughes Medical Institute …
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers
L Brault, C Gasser, F Bracher, K Huber, S Knapp, J Schwaller
haematologica 95 (6), 1004-1015, 2010
Megbízások: Swiss National Science Foundation, Canadian Institutes of Health Research …
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases
O Fedorov, B Marsden, V Pogacic, P Rellos, S Müller, AN Bullock, ...
Proceedings of the National Academy of Sciences 104 (51), 20523-20528, 2007
Megbízások: Genome Canada
Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion
AM Paczulla, K Rothfelder, S Raffel, M Konantz, J Steinbacher, H Wang, ...
Nature 572 (7768), 254-259, 2019
Megbízások: Swiss National Science Foundation, US National Institutes of Health, German …
Programmed death 1 signaling on chronic myeloid leukemia–specific T cells results in T-cell exhaustion and disease progression
S Mumprecht, C Schürch, J Schwaller, M Solenthaler, AF Ochsenbein
Blood, The Journal of the American Society of Hematology 114 (8), 1528-1536, 2009
Megbízások: Swiss National Science Foundation
PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains
S Picaud, D Da Costa, A Thanasopoulou, P Filippakopoulos, PV Fish, ...
Cancer research 73 (11), 3336-3346, 2013
Megbízások: Swiss National Science Foundation, US National Institutes of Health …
Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy
S Picaud, O Fedorov, A Thanasopoulou, K Leonards, K Jones, J Meier, ...
Cancer research 75 (23), 5106-5119, 2015
Megbízások: Swiss National Science Foundation, Canadian Institutes of Health Research …
MLL-AF9 expression in hematopoietic stem cells drives a highly invasive AML expressing EMT-related genes linked to poor outcome
V Stavropoulou, S Kaspar, L Brault, MA Sanders, S Juge, S Morettini, ...
Cancer cell 30 (1), 43-58, 2016
Megbízások: Swiss National Science Foundation, UK Medical Research Council, Swiss Cancer …
Structural analysis identifies imidazo [1, 2-b] pyridazines as PIM kinase inhibitors with in vitro antileukemic activity
V Pogacic, AN Bullock, O Fedorov, P Filippakopoulos, C Gasser, A Biondi, ...
Cancer research 67 (14), 6916-6924, 2007
Megbízások: Genome Canada
Dissection of PIM serine/threonine kinases in FLT3-ITD–induced leukemogenesis reveals PIM1 as regulator of CXCL12–CXCR4-mediated homing and migration
R Grundler, L Brault, C Gasser, AN Bullock, T Dechow, S Woetzel, ...
Journal of experimental medicine 206 (9), 1957-1970, 2009
Megbízások: Swiss National Science Foundation
Bone marrow mesenchymal stem cells support acute myeloid leukemia bioenergetics and enhance antioxidant defense and escape from chemotherapy
D Forte, M García-Fernández, A Sánchez-Aguilera, V Stavropoulou, ...
Cell metabolism 32 (5), 829-843. e9, 2020
Megbízások: Swiss National Science Foundation, Howard Hughes Medical Institute, Banking …
High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors
CV Miduturu, X Deng, N Kwiatkowski, W Yang, L Brault, ...
Chemistry & biology 18 (7), 868-879, 2011
Megbízások: US National Institutes of Health, Canadian Institutes of Health Research …
Estrogen signaling selectively induces apoptosis of hematopoietic progenitors and myeloid neoplasms without harming steady-state hematopoiesis
A Sánchez-Aguilera, L Arranz, D Martín-Pérez, A García-García, ...
Cell stem cell 15 (6), 791-804, 2014
Megbízások: Howard Hughes Medical Institute, Government of Spain
Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia
S Picaud, K Leonards, JP Lambert, O Dovey, C Wells, O Fedorov, ...
Science advances 2 (10), e1600760, 2016
Megbízások: Canadian Institutes of Health Research, Genome Canada, Natural Sciences and …
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