| Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ... Human molecular genetics 16 (22), 2720-2728, 2007 | 503 | 2007 |
| Charcot–Marie–Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport J Brownlees, S Ackerley, AJ Grierson, NJO Jacobsen, K Shea, ... Human molecular genetics 11 (23), 2837-2844, 2002 | 263 | 2002 |
| Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments S Ackerley, P Thornhill, AJ Grierson, J Brownlees, BH Anderton, PN Leigh, ... Journal of Cell Biology 161 (3), 489-495, 2003 | 257 | 2003 |
| Glutamate slows axonal transport of neurofilaments in transfected neurons S Ackerley, AJ Grierson, J Brownlees, P Thornhill, BH Anderton, PN Leigh, ... The Journal of cell biology 150 (1), 165-176, 2000 | 220 | 2000 |
| Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3β transgenes J Brownlees, NG Irving, JP Brion, BJM Gibb, U Wagner, J Woodgett, ... Neuroreport 8 (15), 3251-3255, 1997 | 185 | 1997 |
| Peptidases, peptides, and the mammalian blood–brain barrier J Brownlees, CH Williams Journal of neurochemistry 60 (3), 793-803, 1993 | 172 | 1993 |
| Phosphorylation of thr668 in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress‐activated protein kinase 1b (Jun N‐terminal … CL Standen, J Brownlees, AJ Grierson, S Kesavapany, KF Lau, ... Journal of neurochemistry 76 (1), 316-320, 2001 | 160 | 2001 |
| p38α stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis S Ackerley, AJ Grierson, S Banner, MS Perkinton, J Brownlees, HL Byers, ... Molecular and Cellular Neuroscience 26 (2), 354-364, 2004 | 147 | 2004 |
| Axonal transport of neurofilaments in normal and disease states CCJ Miller, S Ackerley, J Brownlees, AJ Grierson, NJO Jacobsen, ... Cellular and Molecular Life Sciences CMLS 59, 323-330, 2002 | 135 | 2002 |
| Phosphorylation of neurofilament heavy chain side-arms by stress activated protein kinase-1b/Jun N-terminal kinase-3 J Brownlees, A Yates, NP Bajaj, D Davis, BH Anderton, PN Leigh, ... Journal of Cell Science 113 (3), 401-407, 2000 | 126 | 2000 |
| p35/cdk5 binds and phosphorylates β‐catenin and regulates β‐catenin/presenilin‐1 interaction S Kesavapany, KF Lau, DM McLoughlin, J Brownlees, S Ackerley, ... European Journal of Neuroscience 13 (2), 241-247, 2001 | 122 | 2001 |
| ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth EL Tudor, MS Perkinton, A Schmidt, S Ackerley, J Brownlees, ... Journal of biological chemistry 280 (41), 34735-34740, 2005 | 101 | 2005 |
| Mint2/X11‐like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease DM McLoughlin, NG Irving, J Brownlees, JP Brion, K Leroy, CCJ Miller European journal of neuroscience 11 (6), 1988-1994, 1999 | 100 | 1999 |
| Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X G Antonios, H Borgers, BC Richard, A Brauß, J Meißner, S Weggen, ... Scientific reports 5 (1), 17338, 2015 | 65 | 2015 |
| Overexpression of the mouse dishevelled-1 protein inhibits GSK-3β-mediated phosphorylation of tau in transfected mammalian cells U Wagner, J Brownlees, NG Irving, FR Lucas, PC Salinas, CCJ Miller FEBS letters 411 (2-3), 369-372, 1997 | 65 | 1997 |
| Neuropathological abnormalities in transgenic mice harbouring a phosphorylation mutant neurofilament transgene BJM Gibb, JP Brion, J Brownlees, BH Anderton, CCJ Miller Journal of neurochemistry 70 (2), 492-500, 1998 | 58 | 1998 |
| Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF TM Chapman, KJ Gillen, C Wallace, MT Lee, P Bakrania, P Khurana, ... Bioorganic & Medicinal Chemistry Letters 25 (19), 4097-4103, 2015 | 32 | 2015 |
| Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses E Redondo-Castro, D Faust, S Fox, AG Baldwin, S Osborne, MJ Haley, ... Scientific reports 8 (1), 5667, 2018 | 30 | 2018 |
| N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1–XPF TM Chapman, C Wallace, KJ Gillen, P Bakrania, P Khurana, PJ Coombs, ... Bioorganic & medicinal chemistry letters 25 (19), 4104-4108, 2015 | 27 | 2015 |
| Inhibition of IL-34 unveils tissue-selectivity and is sufficient to reduce microglial proliferation in a model of chronic neurodegeneration J Obst, E Simon, M Martin-Estebane, E Pipi, LM Barkwill, ... Frontiers in immunology 11, 579000, 2020 | 22 | 2020 |
