Functional characterization of the dural sinuses as a neuroimmune interface J Rustenhoven, A Drieu, T Mamuladze, KA de Lima, T Dykstra, M Wall, ... Cell 184 (4), 1000-1016. e27, 2021 | 495 | 2021 |
Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma A Cugurra, T Mamuladze, J Rustenhoven, T Dykstra, G Beroshvili, ... Science 373 (6553), eabf7844, 2021 | 464 | 2021 |
Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy S Da Mesquita, Z Papadopoulos, T Dykstra, L Brase, FG Farias, M Wall, ... Nature 593 (7858), 255-260, 2021 | 283 | 2021 |
Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease JS Sadick, MR O’Dea, P Hasel, T Dykstra, A Faustin, SA Liddelow Neuron 110 (11), 1788-1805. e10, 2022 | 256 | 2022 |
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid A Drieu, S Du, SE Storck, J Rustenhoven, Z Papadopoulos, T Dykstra, ... Nature 611 (7936), 585-593, 2022 | 177 | 2022 |
Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels JA Mazzitelli, LCD Smyth, KA Cross, T Dykstra, J Sun, S Du, T Mamuladze, ... Nature neuroscience 25 (5), 555-560, 2022 | 162 | 2022 |
Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology S Da Mesquita, J Herz, M Wall, T Dykstra, KA de Lima, GT Norris, N Dabhi, ... Science Advances 7 (21), eabe4601, 2021 | 123 | 2021 |
Identification of direct connections between the dura and the brain LCD Smyth, D Xu, SV Okar, T Dykstra, J Rustenhoven, Z Papadopoulos, ... Nature 627 (8002), 165-173, 2024 | 85 | 2024 |
GABAergic neuronal IL-4R mediates T cell effect on memory J Herz, Z Fu, K Kim, T Dykstra, M Wall, H Li, AF Salvador, B Zou, N Yan, ... Neuron 109 (22), 3609-3618. e9, 2021 | 70 | 2021 |
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers L Brase, SF You, R D’Oliveira Albanus, JL Del-Aguila, Y Dai, BC Novotny, ... Nature communications 14 (1), 2314, 2023 | 44 | 2023 |
Age-related alterations in meningeal immunity drive impaired CNS lymphatic drainage J Rustenhoven, G Pavlou, SE Storck, T Dykstra, S Du, Z Wan, D Quintero, ... Journal of Experimental Medicine 220 (7), e20221929, 2023 | 39 | 2023 |
Age-dependent immune and lymphatic responses after spinal cord injury AFM Salvador, T Dykstra, J Rustenhoven, W Gao, SM Blackburn, ... Neuron 111 (14), 2155-2169. e9, 2023 | 22 | 2023 |
Patient‐Reported Outcome Measures: Utility for Predicting Spinal Surgery in an Integrated Spine Practice JR Babington, A Edwards, AK Wright, T Dykstra, AS Friedman, RK Sethi PM&R 10 (7), 724-729, 2018 | 15 | 2018 |
Age-associated suppression of exploratory activity during sickness is linked to meningeal lymphatic dysfunction and microglia activation DH Goldman, T Dykstra, I Smirnov, SM Blackburn, S Da Mesquita, ... Nature aging 2 (8), 704-713, 2022 | 12 | 2022 |
Engineered T cell therapy for central nervous system injury W Gao, MW Kim, T Dykstra, S Du, P Boskovic, CF Lichti, ... Nature 634 (8034), 693-701, 2024 | 8 | 2024 |
A novel immune modulator IM33 mediates a glia-gut-neuronal axis that controls lifespan W Xu, J Rustenhoven, CA Nelson, T Dykstra, A Ferreiro, Z Papadopoulos, ... Neuron 111 (20), 3244-3254. e8, 2023 | 7 | 2023 |
Endogenous self-peptides guard immune privilege of the central nervous system MW Kim, W Gao, CF Lichti, X Gu, T Dykstra, J Cao, I Smirnov, P Boskovic, ... Nature 637 (8044), 176-183, 2025 | 5 | 2025 |
MENINGES HARBOR IMMUNE MEMORIES OF LIFE EXPERIENCES UIN DEMENTIA Innovation in Aging 6 (S1), 347, 2022 | | 2022 |