Követés
Ben Sidders
Ben Sidders
Oncology R&D, Astrazeneca
E-mail megerősítve itt: astrazeneca.com
Cím
Hivatkozott rá
Hivatkozott rá
Év
Ion Channels as Therapeutic Targets: A Drug Discovery Perspective
SK Bagal, AD Brown, PJ Cox, K Omoto, RM Owen, DC Pryde, B Sidders, ...
Journal of Medicinal Chemistry, 2012
3442012
A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis
SL Kendall, M Withers, CN Soffair, NJ Moreland, S Gurcha, B Sidders, ...
Molecular microbiology 65 (3), 684-699, 2007
2702007
Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon
N Shimono, L Morici, N Casali, S Cantrell, B Sidders, S Ehrt, LW Riley
Proceedings of the national academy of sciences 100 (26), 15918-15923, 2003
2692003
HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain
F Denk, W Huang, B Sidders, A Bithell, M Crow, J Grist, S Sharma, ...
Pain® 154 (9), 1668-1679, 2013
1622013
Causal reasoning on biological networks: interpreting transcriptional changes
L Chindelevitch, D Ziemek, A Enayetallah, R Randhawa, B Sidders, ...
Bioinformatics 28 (8), 1114-1121, 2012
1542012
Screening of Highly Expressed Mycobacterial Genes Identifies Rv3615c as a Useful Differential Diagnostic Antigen for the Mycobacterium tuberculosis Complex
B Sidders, C Pirson, PJ Hogarth, RG Hewinson, NG Stoker, ...
Infection and immunity 76 (9), 3932-3939, 2008
1402008
5′‐Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice
RH Senaratne, AD De Silva, SJ Williams, JD Mougous, JR Reader, ...
Molecular microbiology 59 (6), 1744-1753, 2006
1282006
Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice
RH Senaratne, B Sidders, P Sequeira, G Saunders, K Dunphy, ...
Journal of medical microbiology 57 (2), 164-170, 2008
1252008
Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens
E Goncalves, A Segura-Cabrera, C Pacini, G Picco, F Behan, P Jaaks, ...
bioRxiv, 2020
882020
Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens
E Goncalves, A Segura-Cabrera, C Pacini, G Picco, F Behan, P Jaaks, ...
bioRxiv, 2020
882020
PI3Kα/δ inhibition promotes anti-tumor immunity through direct enhancement of effector CD8+ T-cell activity
LS Carnevalli, C Sinclair, MA Taylor, PM Gutierrez, S Langdon, ...
Journal for immunotherapy of cancer 6 (1), 158, 2018
862018
Genes contributing to pain sensitivity in the normal population: an exome sequencing study
FMK Williams, S Scollen, D Cao, Y Memari, CL Hyde, B Zhang, B Sidders, ...
PLoS genetics 8 (12), e1003095, 2012
742012
Adenosine signalling is prognostic for cancer outcome and has predictive utility for immunotherapeutic response
B Sidders, P Zhang, K Goodwin, G O'Connor, DL Russell, A Borodovsky, ...
Clinical Cancer Research, 2020
732020
Selection, optimization, and pharmacokinetic properties of a novel, potent antiviral locked nucleic acid-based antisense oligomer targeting hepatitis C virus internal ribosome …
C Laxton, K Brady, S Moschos, P Turnpenny, J Rawal, DC Pryde, ...
Antimicrobial agents and chemotherapy 55 (7), 3105-3114, 2011
682011
Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer
A Gogleva, D Polychronopoulos, M Pfeifer, V Poroshin, M Ughetto, ...
Nature communications 13 (1), 1667, 2022
672022
Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks
CT Fakhry, P Choudhary, A Gutteridge, B Sidders, P Chen, D Ziemek, ...
BMC bioinformatics 17, 1-15, 2016
572016
Network-based drug discovery: coupling network pharmacology with phenotypic screening for neuronal excitability
B Sidders, A Karlsson, L Kitching, R Torella, P Karila, A Phelan
Journal of molecular biology 430 (18), 3005-3015, 2018
512018
The pain interactome: connecting pain-specific protein interactions
DG Jamieson, A Moss, M Kennedy, S Jones, G Nenadic, DL Robertson, ...
PAIN® 155 (11), 2243-2252, 2014
472014
Phase ia/b, open-label, multicenter study of AZD4635 (an adenosine A2A receptor antagonist) as monotherapy or combined with durvalumab, in patients with solid tumors
EA Lim, JC Bendell, GS Falchook, TM Bauer, CG Drake, JH Choe, ...
Clinical Cancer Research 28 (22), 4871-4884, 2022
452022
Quantification of global transcription patterns in prokaryotes using spotted microarrays
B Sidders, M Withers, SL Kendall, J Bacon, SJ Waddell, J Hinds, P Golby, ...
Genome Biology 8, 1-13, 2007
422007
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