Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity T Vavouri, JI Semple, R Garcia-Verdugo, B Lehner Cell 138 (1), 198-208, 2009 | 429 | 2009 |
Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery I Mamely, MATM van Vugt, VAJ Smits, JI Semple, B Lemmens, A Perrakis, ... Current Biology 16 (19), 1950-1955, 2006 | 277 | 2006 |
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network G Markson, C Kiel, R Hyde, S Brown, P Charalabous, A Bremm, J Semple, ... Genome research 19 (10), 1905-1911, 2009 | 210 | 2009 |
Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region B Lehner, JI Semple, SE Brown, D Counsell, RD Campbell, ... Genomics 83 (1), 153-167, 2004 | 139 | 2004 |
Widespread conservation of genetic redundancy during a billion years of eukaryotic evolution T Vavouri, JI Semple, B Lehner Trends in genetics 24 (10), 485-488, 2008 | 115 | 2008 |
Predicting phenotypic variation in yeast from individual genome sequences R Jelier, JI Semple, R Garcia-Verdugo, B Lehner Nature genetics 43 (12), 1270-1274, 2011 | 88 | 2011 |
Rapid selection of transgenic C. elegans using antibiotic resistance JI Semple, R Garcia-Verdugo, B Lehner Nature methods 7 (9), 725-727, 2010 | 82 | 2010 |
The human two domain trefoil protein, TFF2, is glycosylated in vivo in the stomach FEB May, JI Semple, JL Newton, BR Westley Gut 46 (4), 454-459, 2000 | 57 | 2000 |
Cleavage and degradation of Claspin during apoptosis by caspases and the proteasome JI Semple, VAJ Smits, JR Fernaud, I Mamely, R Freire Cell Death & Differentiation 14 (8), 1433-1442, 2007 | 52 | 2007 |
Dramatic diurnal variation in the concentration of the human trefoil peptide TFF2 in gastric juice JI Semple, JL Newton, BR Westley, FEB May Gut 48 (5), 648-655, 2001 | 52 | 2001 |
Generating transgenic nematodes by bombardment and antibiotic selection JI Semple, L Biondini, B Lehner Nature methods 9 (2), 118-119, 2012 | 40 | 2012 |
A simple principle concerning the robustness of protein complex activity to changes in gene expression JI Semple, T Vavouri, B Lehner BMC systems biology 2, 1-7, 2008 | 37 | 2008 |
Expression and motogenic activity of TFF2 in human breast cancer cells FEB May, JI Semple, SJ Prest, BR Westley Peptides 25 (5), 865-872, 2004 | 35 | 2004 |
A distinct bipartite motif is required for the localization of inhibitory κB-like (IκBL) protein to nuclear speckles JI Semple, SE Brown, CM Sanderson, RD Campbell Biochemical Journal 361 (3), 489-496, 2002 | 32 | 2002 |
The jury is out on ‘guilt by association’trials JI Semple, CM Sanderson, RD Campbell Briefings in Functional Genomics 1 (1), 40-52, 2002 | 26 | 2002 |
Tissue-Specific Transcription Footprinting Using RNA PoI DamID (RAPID) in Caenorhabditis elegans G Gómez-Saldivar, J Osuna-Luque, JI Semple, DA Glauser, S Jarriault, ... Genetics 216 (4), 931-945, 2020 | 25 | 2020 |
Two-hybrid reporter vectors for gap repair cloning JI Semple, G Prime, LJ Wallis, CM Sanderson, D Markie Biotechniques 38 (6), 927-934, 2005 | 21 | 2005 |
A novel gene encoding a coiled-coil mitochondrial protein located at the telomeric end of the human MHC Class III region JI Semple, G Ribas, G Hillyard, SE Brown, CM Sanderson, RD Campbell Gene 314, 41-54, 2003 | 16 | 2003 |
Cohesin forms fountains at active enhancers in C. elegans BN Isiaka, JI Semple, A Haemmerli, S Thapliyal, K Stojanovski, M Das, ... BioRxiv, 2023.07. 14.549011, 2023 | 13 | 2023 |
Condensin I folds the C. elegans genome M Das, JI Semple, V Volodkina, A Haemmerli, J Scotton, T Gitchev, ... bioRxiv, 2022.06. 14.495661, 2022 | 10 | 2022 |