Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling SMA Huang, YM Mishina, S Liu, A Cheung, F Stegmeier, GA Michaud, ... Nature 461 (7264), 614-620, 2009 | 2280 | 2009 |
Bidirectional transport of amino acids regulates mTOR and autophagy P Nicklin, P Bergman, B Zhang, E Triantafellow, H Wang, B Nyfeler, ... Cell 136 (3), 521-534, 2009 | 2045 | 2009 |
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS UB Pandey, Z Nie, Y Batlevi, BA McCray, GP Ritson, NB Nedelsky, ... Nature 447 (7146), 860-864, 2007 | 1466 | 2007 |
Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide ES Fischer, K Böhm, JR Lydeard, H Yang, MB Stadler, S Cavadini, ... Nature 512 (7512), 49-53, 2014 | 1092 | 2014 |
Genome-Wide RNAi Analysis of Growth and Viability in Drosophila Cells M Boutros, AA Kiger, S Armknecht, K Kerr, M Hild, B Koch, SA Haas, ... Science 303 (5659), 832-835, 2004 | 896 | 2004 |
RNF146 is a poly (ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling Y Zhang, S Liu, C Mickanin, Y Feng, O Charlat, GA Michaud, M Schirle, ... Nature cell biology 13 (5), 623-629, 2011 | 457 | 2011 |
SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice J Palacino, SE Swalley, C Song, AK Cheung, L Shu, X Zhang, ... Nature chemical biology 11 (7), 511-517, 2015 | 452 | 2015 |
Zebrafish ΔNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm J Bakkers, M Hild, C Kramer, M Furutani-Seiki, M Hammerschmidt Developmental cell 2 (5), 617-627, 2002 | 279 | 2002 |
Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo A Dick, M Hild, H Bauer, Y Imai, H Maifeld, AF Schier, WS Talbot, ... Development 127 (2), 343-354, 2000 | 262 | 2000 |
Notch2 is required for inflammatory cytokine-driven goblet cell metaplasia in the lung H Danahay, AD Pessotti, J Coote, BE Montgomery, D Xia, A Wilson, ... Cell reports 10 (2), 239-252, 2015 | 259 | 2015 |
The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo M Hild, A Dick, GJ Rauch, A Meier, T Bouwmeester, P Haffter, ... Development 126 (10), 2149-2159, 1999 | 226 | 1999 |
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5 H Ruffner, J Sprunger, O Charlat, J Leighton-Davies, B Grosshans, ... PloS one 7 (7), e40976, 2012 | 216 | 2012 |
DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery C Ye, DJ Ho, M Neri, C Yang, T Kulkarni, R Randhawa, M Henault, ... Nature communications 9 (1), 4307, 2018 | 195 | 2018 |
Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila O Bell, C Wirbelauer, M Hild, AND Scharf, M Schwaiger, DM MacAlpine, ... The EMBO journal 26 (24), 4974-4984, 2007 | 182 | 2007 |
Discovery of small molecule splicing modulators of survival motor neuron-2 (SMN2) for the treatment of spinal muscular atrophy (SMA) AK Cheung, B Hurley, R Kerrigan, L Shu, DN Chin, Y Shen, G O’Brien, ... Journal of medicinal chemistry 61 (24), 11021-11036, 2018 | 139 | 2018 |
An integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genome M Hild, B Beckmann, SA Haas, B Koch, V Solovyev, C Busold, ... Genome biology 5, 1-17, 2003 | 137 | 2003 |
Follistatin and noggin are excluded from the zebrafish organizer H Bauer, A Meier, M Hild, S Stachel, A Economides, D Hazelett, ... Developmental biology 204 (2), 488-507, 1998 | 132 | 1998 |
Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance B Lu, I Al-Ramahi, A Valencia, Q Wang, F Berenshteyn, H Yang, ... Nature neuroscience 16 (5), 562-570, 2013 | 107 | 2013 |
Production of 3‐D airway organoids from primary human airway basal cells and their use in high‐throughput screening M Hild, AB Jaffe Current protocols in stem cell biology 37 (1), IE. 9.1-IE. 9.15, 2016 | 101 | 2016 |
Comparing active and repressed expression states of genes controlled by the Polycomb/Trithorax group proteins C Beisel, A Buness, IM Roustan-Espinosa, B Koch, S Schmitt, SA Haas, ... Proceedings of the National Academy of Sciences 104 (42), 16615-16620, 2007 | 97 | 2007 |