Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16 T Li, BA Diner, J Chen, IM Cristea Proceedings of the National Academy of Sciences 109 (26), 10558-10563, 2012 | 373 | 2012 |
cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection MH Orzalli, NM Broekema, BA Diner, DC Hancks, NC Elde, IM Cristea, ... Proceedings of the National Academy of Sciences 112 (14), E1773-E1781, 2015 | 286 | 2015 |
Viral DNA sensors IFI16 and cyclic GMP-AMP synthase possess distinct functions in regulating viral gene expression, immune defenses, and apoptotic responses during herpesvirus … BA Diner, KK Lum, JE Toettcher, IM Cristea MBio 7 (6), e01553-16, 2016 | 160 | 2016 |
The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA BA Diner, T Li, TM Greco, MS Crow, JA Fuesler, J Wang, IM Cristea Molecular systems biology 11 (2), 2015 | 120 | 2015 |
Interactions of the antiviral factor interferon gamma-inducible protein 16 (IFI16) mediate immune signaling and herpes simplex virus-1 immunosuppression BA Diner, KK Lum, A Javitt, IM Cristea Molecular & Cellular Proteomics 14 (9), 2341-2356, 2015 | 110 | 2015 |
The emerging role of nuclear viral DNA sensors BA Diner, KK Lum, IM Cristea Journal of Biological Chemistry 290 (44), 26412-26421, 2015 | 87 | 2015 |
The impact of mass spectrometry–based proteomics on fundamental discoveries in virology TM Greco, BA Diner, IM Cristea Annual review of virology 1, 581-604, 2014 | 78 | 2014 |
Two modes of the axonal interferon response limit alphaherpesvirus neuroinvasion R Song, OO Koyuncu, TM Greco, BA Diner, IM Cristea, LW Enquist MBio 7 (1), e02145-15, 2016 | 62 | 2016 |
Histone deacetylases in herpesvirus replication and virus-stimulated host defense AJ Guise, HG Budayeva, BA Diner, IM Cristea Viruses 5 (7), 1607-1632, 2013 | 50 | 2013 |
Interactome and proteome dynamics uncover immune modulatory associations of the pathogen sensing factor cGAS KK Lum, B Song, JD Federspiel, BA Diner, T Howard, IM Cristea Cell systems 7 (6), 627-642. e6, 2018 | 41 | 2018 |
Mai1 Protein Acts Between Host Recognition of Pathogen Effectors and Mitogen-Activated Protein Kinase Signaling R Roberts, SR Hind, KF Pedley, BA Diner, MJ Szarzanowicz, ... Molecular Plant-Microbe Interactions 32 (11), 1496-1507, 2019 | 18 | 2019 |
Interactions of the antiviral factor IFI16 mediate immune signaling and herpes simplex virus-1 immunosuppression BA Diner, KK Lum, A Javitt, IM Cristea Molecular & Cellular Proteomics, 2015 | 13 | 2015 |
Blowing off steam: virus inhibition of cGAS DNA sensing BA Diner, IM Cristea Cell host & microbe 18 (3), 270-272, 2015 | 9 | 2015 |
Treatment of Herpetic Keratitis with CRISPR/Cas9 Gene Editing in a Rabbit Disease Model S Shen, CM Owens, H Chao, CJ Yudkoff, B Diner, R Fusco, D Tabbaa, ... MOLECULAR THERAPY 26 (5), 128-128, 2018 | 1 | 2018 |
Mai1 protein acts between host recognition of pathogen effectors and MAPK signaling SR Hind, R Roberts, KF Pedley, BA Diner, MJ Szarzanowicz, ... BioRxiv, 529172, 2019 | | 2019 |
CRISPR/Cas9 Targeted Disruption of Herpes Simplex Virus type 1 in a Rabbit Latency Model Reduces Viral Reactivation and Associated Corneal Pathology CM Owens, B Diner, R Fusco, E King, AE Friedland, P Singhal, K Gogi, ... Investigative Ophthalmology & Visual Science 59 (9), 2018 | | 2018 |
An integrative approach delineating the critical functions of antiviral protein IFI16 BA Diner Princeton University, 2016 | | 2016 |
Local Interferon Responses in Axons Limit Retrograde Transport of an Alpha Herpesvirus in Neurons R Song, OO Koyuncu, TM Greco, BA Diner, IM Cristea, LW Enquist JOURNAL OF NEUROVIROLOGY 21, S70-S71, 2015 | | 2015 |